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Carakostas MC Power RJ Banerjee AK 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1990,19(4):109-113
A manual kit for determining serum 5'nucleotidase (5'NT, EC 3.1.3.5) activity was adapted for use with rat samples on a large discrete clinical chemistry analyzer. The precision of the method was good (within-run C.V. = 2.14%; between-run C.V. = 5.5%). A comparison of the new automated method with a manual and semi-automated method gave regression statistics of y = 1.18X -3.66 (Sy. x = 4.54), and y = 0.733X + 1.97 (Sy. x = 1.69), respectively. Temperature conversion factors provided by the kit manufacturer for human samples were determined to be inaccurate for converting results from rat samples. Analysis of components contributing to normal variation in rat serum 5'NT activity showed age and sex to be major factors. Increased serum 5'NT activity was observed in female rats when compared to male rats beginning at about 5 to 6 weeks of age. An analysis of variance of serum 5'NT, alkaline phosphatase, and GGT activities observed over a 9-week period in normal rats suggests several advantages for 5'NT as a predictor of biliary lesions in rats. 相似文献
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C. G. Campbell R. B. Mehra S. K. Agrawal Y. Z. Chen A. M. Abd El Moneim H. I. T. Khawaja C. R. Yadov J. U. Tay W. A. Araya 《Euphytica》1993,73(1-2):167-175
Efforts in grasspea (Lathyrus sativus) improvement have increased since the development of lines that are very low in the neurotoxin Beta-N-oxalyl-L-alpha-beta-diamino propionic acid (ODAP); also referred to as Beta-N oxalyl-amino-L-alanine (BOAA). Many programs now address several related aspects of improvement simultaneously. These include reduced ODAP concentrations, insect and disease resistance, nitrogen fixation, agronomic practices, fodder and forage production, and components for increased yielding ability. The coordinated, multidisciplinary approach now being applied to the genetic improvement of grasspea should allow the potential of this largely neglected grain legume to be fully realized. 相似文献
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除草剂阿特拉津影响大鼠脏器功能的毒理学研究 总被引:17,自引:0,他引:17
试验研究了除草剂阿特拉津对大鼠脏器功能的影响。选用SD大鼠120只.雌雄各半,随机分成4组.分别按每千克体重200mg,100mg,10mg,0mg,设置高、中、低剂量3个处理组和1个对照组,药物配成乳浊液灌胃.并于喂药15d和30d采样测定甲状腺、胸腺、心脏、肺脏、肝脏、脾脏、肾脏、生殖腺等脏器与体重的相对比值。实验结果表明:阿特拉津对动物的代谢器官(肝脏、肾脏)具有损伤作用,使其发生退行性病变,中、高剂量组损伤作用尤为明显;阿特拉津使大鼠的免疫器官——胸腺、脾脏发生退行性病变,高剂量组损伤作用最为明显;雄性大鼠睾丸发生退行性病变,雌性大鼠卵巢则出现增生性病变,进而可能影响到大鼠的生殖功能。 相似文献