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31.
Farid Menaa P. A. U. I. Wijesinghe Gobika Thiripuranathar Bushra Uzair Haroon Iqbal Barkat Ali Khan Bouzid Menaa 《Marine drugs》2020,18(12)
Seaweeds are broadly distributed and represent an important source of secondary metabolites (e.g., halogenated compounds, polyphenols) eliciting various pharmacological activities and playing a relevant ecological role in the anti-epibiosis. Importantly, host (as known as basibiont such as algae)–microbe (as known as epibiont such as bacteria) interaction (as known as halobiont) is a driving force for coevolution in the marine environment. Nevertheless, halobionts may be fundamental (harmless) or detrimental (harmful) to the functioning of the host. In addition to biotic factors, abiotic factors (e.g., pH, salinity, temperature, nutrients) regulate halobionts. Spatiotemporal and functional exploration of such dynamic interactions appear crucial. Indeed, environmental stress in a constantly changing ocean may disturb complex mutualistic relations, through mechanisms involving host chemical defense strategies (e.g., secretion of secondary metabolites and antifouling chemicals by quorum sensing). It is worth mentioning that many of bioactive compounds, such as terpenoids, previously attributed to macroalgae are in fact produced or metabolized by their associated microorganisms (e.g., bacteria, fungi, viruses, parasites). Eventually, recent metagenomics analyses suggest that microbes may have acquired seaweed associated genes because of increased seaweed in diets. This article retrospectively reviews pertinent studies on the spatiotemporal and functional seaweed-associated microbiota interactions which can lead to the production of bioactive compounds with high antifouling, theranostic, and biotechnological potential. 相似文献
32.
Shahid Iqbal Shahzad M. A. Basra Irfan Afzal Abdul Wahid Muhammad S. Saddiq Muhammad B. Hafeez Sven‐Erik Jacobsen 《Journal of Agronomy and Crop Science》2019,205(1):13-21
Quinoa is recently introduced to Pakistan as a salt‐tolerant crop of high nutritional value. Open field trials were conducted to evaluate its performance on normal and salinity/sodicity‐degraded lands at two locations of different salinity/sodicity levels, S1 (UAF Farm, Normal Soil), S2 (Paroka Farm UAF, saline sodic), S3 (SSRI Farm, normal) and S4 (SSRI Farm, saline sodic) during 2013–2014. Two genotypes (Q‐2 and Q‐7) were grown in lines and were allowed to grow till maturity under RCBD split‐plot arrangement. Maximum seed yield (3,062 kg/ha) was achieved by Q‐7 at normal field (S1) soil which was statistically similar with yield of same genotype obtained from salt‐affected field S2 (2,870 kg/ha). Furthermore, low yield was seen from both genotypes from both S3 and S4 as compared to S1 and S2. Q‐7 was best under all four conditions. Minimum yield was recorded from Q‐2 (1,587 kg/ha) at S4. Q‐7 had higher SOD, proline, phenolic and K+ contents, and lower Na+ content in leaves as compared to Q‐2. High levels of antioxidants and K+/Na+ of Q‐7 helped to withstand salt stress and might be the cause of higher yields under both normal and salt‐affected soils. Seed quality (mineral and protein) did not decrease considerably under salt‐affected soils even improved seed K+, Mg2+ and Mn2+. 相似文献
33.
Muhammad Omer Aijaz Sajjad Haider Fahad S. Al-Mubaddel Rawaiz Khan Adnan Haider Abdulaziz Abdullah Alghyamah Waheed A. Almasry Mohammad Sherjeel Javed Khan Muhammad Javid Wajahat Ur Rehman 《Fibers and Polymers》2017,18(4):611-618
The present study is focused on studying the swelling kinetics, thermal and aqueous stabilities, and determination of various forms of water in the chitosan (CS) and polyacrylonitrile (PAN) blend and semi-interpenetrating polymer network (sIPN). CS/PAN blend hydrogel films were prepared by solution casting technique. The blend film with optimum swelling properties was selected for the synthesis of sIPN. CS in the blend was crosslinked with the vapors of Glutaraldehyde (GTA) to prepare sIPN. The fabricated CS/PAN blend and sIPN hydrogels films were characterized with Fourier transform infrared (FTIR), thermal gravimetric analysis (TGA) and field emission scanning electron microscope (FESEM). The kinetics of swelling, bound and unbound waters and aqueous stability were determined experimentally. FESEM showed good miscibility between CS and PAN, FTIR showed no chemical interaction between CS and PAN; however, it did show a doublet for the sIPN, TGA showed improved thermal stability and swelling kinetic followed second order kinetics. The degree of swelling of the sIPN hydrogels samples at room temperature varied from ~2200 % (with a fair degree of stability (~30 %)) to ~1000 % (with high degree of aqueous stability (43 %)) with increase in the crosslinking time. The calculated unbound water (WUB) max., for the blend was 52.3 % whereas for the bound (WB) the max., was 41.9 %. However, for sIPN hydrogel films, the WUB water decreased (max. 21.0 %) where as the WB increased (max. 52.0 %). The decrease in WUB and increase in the WB is attributed to the formation of a compact structure and increase in the contact area between the water and polymers in sIPN hydrogels due to the induction of new water contacting point in these hydrogel films, respectively. 相似文献
34.
Genome-wide association analysis for stripe rust resistance in spring wheat(Triticum aestivum L.) germplasm 下载免费PDF全文
Sher MUHAMMAD Muhammad SAJJAD Sultan Habibullah KHAN Muhammad SHAHID Muhammad ZUBAIR Faisal Saeed AWAN Azeem Iqbal KHAN Muhammad Salman MUBARAK Ayesha TAHIR Muhammad Umer Rumana KEYANI Muhammad Inam AFZAL Irfan MANZOOR Javed Iqbal WATTOO Aziz-ur REHMAN 《农业科学学报》2020,19(8):2035-2043
Stripe rust is a continuous threat to wheat crop all over the world. It causes considerable yield losses in wheat crop every year. Continuous deployment of adult plant resistance(APR) genes in newly developing wheat cultivars is the most judicious strategy to combat this disease. Herein, we dissected the genetics underpinning stripe rust resistance in Pakistani wheat germplasm. An association panel of 94 spring wheat genotypes was phenotyped for two years to score the infestation of stripe rust on each accession and was scanned with 203 polymorphic SSRs. Based on D' measure, linkage disequilibrium(LD) exhibited between loci distant up to 45 c M. Marker-trait associations(MTAs) were determined using mixed linear model(MLM). Total 31 quantitative trait loci(QTLs) were observed on all 21 wheat chromosomes. Twelve QTLs were newly discovered as well as 19 QTLs and 35 previously reported Yr genes were validated in Pakistani wheat germplasm. The major QTLs were QYr.uaf.2 AL and QYr.uaf.3 BS(PVE, 11.9%). Dissection of genes from the newly observed QTLs can provide new APR genes to improve genetic resources for APR resistance in wheat crop. 相似文献
35.
Mohd. Iqbal Yatoo Oveas Raffiq Parray Shah Tauseef Bashir Muheet Riyaz Ahmed Bhat Arumugam Gopalakrishnan 《The Veterinary quarterly》2019,39(1):1-25
Contagious caprine pleuropneumonia (CCPP) is a serious disease of goats, occasionally sheep and wild ruminants, caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp). The disease is characterized by severe serofibrinous pleuropneumonia, very high morbidity (~100%), and mortality (80–100%). CCPP affects goats in more than 40 countries of the world thereby posing a serious threat to goat farming around the globe. The characteristic clinical signs of CCPP are severe respiratory distress associated with sero-mucoid nasal discharge, coughing, dyspnea, pyrexia, pleurodynia, and general malaise. In later stages, severe lobar fibrinous pleuropneumonia, profuse fluid accumulation in pleural cavity, severe congestion of lungs and adhesion formation is observed. Mycoplasmal antigen interactions with host immune system and its role in CCPP pathogenesis are not clearly understood. CCPP is not a zoonotic disease. Diagnosis has overcome cumbersome and lengthy conventional tests involving culture, isolation, and identification by advanced serological (LAT, cELISA) or gene-based amplification of DNA (PCR, RFLP, and hybridization) and sequencing. The latex agglutination test (LAT) is rapid, simple, and better test for field and real-time diagnosis applicable to whole blood or serum and is more sensitive than the CFT and easier than the cELISA. Moreover, the studies on antibiotic sensitivity and exploration of novel antibiotics (fluoroquinolones, macrolides) can help in better therapeutic management besides preventing menace of antibiotic resistance. Re-visiting conventional prophylactic measures focussing on developing novel strain-based or recombinant vaccines using specific antigens (capsular or cellular) should be the most important strategy for controlling the disease worldwide. 相似文献
36.
Yatoo Mohd. Iqbal Parray Oveas Raffiq Mir Muheet Bhat Riyaz Ahmed Malik Hamid Ullah Fazili Mujeeb ur Rehman Qureshi Sabia Mir Masood Salim Yousuf Raja Wasim Tufani Noor Alam Dhama Kuldeep Bashir Shah Tauseef 《Tropical animal health and production》2019,51(8):2127-2137
Tropical Animal Health and Production - Therapeutic management of contagious caprine pleuroneumonia (CCPP) involves mostly the use of oxytetracycline followed by enrofloxacin and rarely tylosin. In... 相似文献
37.
Sehrish Iqbal Aqeel Javeed Adeel Sattar Rabia Tanvir 《Journal of veterinary pharmacology and therapeutics》2019,42(6):707-712
Thymoquinone (TQ) is the major constituent of Nigella sativa and known to possess a variety of pharmacological effects. This study was designed to evaluate the pharmacokinetic profile of TQ following oral (PO) and intravenous (IV) administration in layer chickens. The layer chickens were equally divided into two groups (six chickens in each group, total 12 chickens), and TQ was administered via PO and IV routes. For PO route, the dose was 20 mg/kg b.w. and for IV route, 5 mg/kg b.w. was administered, respectively. A sensitive and accurate High‐Performance Liquid Chromatography (HPLC) technique was validated for the quantification of TQ from plasma. The limit of detection (LOD) and limit of quantification (LOQ) were 0.02 µg/ml and 0.05 µg/ml, respectively with >80% recovery. Maximum plasma concentration (Cmax) following PO and IV administration was 8.805 and 4.497 µg/ml, respectively, while time to reach at maximum concentration (Tmax) was 1 and 0.1 hr, respectively. The elimination half‐lives were recorded as 1.02 and 0.978 hr, whereas the mean residence times were 1.79 and 1.036 hr following both PO and IV administration, respectively. The 85% PO bioavailability was indicative that TQ could be used for various therapeutic purposes in layer chickens. 相似文献
38.
Rashid J Weiss DJ Murtaugh MP Bach R 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1997,26(4):198-202
Tissue factor (TF), a cell surface-associated cofactor and activator of coagulation factor VII, has been implicated in the local and systemic activation of coagulation associated with sepsis. This study describes the pattern of TF expression in experimental bovine pneumonic pasteurellosis and endotoxemia. Immunohistochemical techniques were used to localize TF antigen in tissue sections. Tissue factor expression was not observed in tissues from control animals. In response to Pasteurella haemolytica challenge, TF was expressed within alveolar walls, by mononuclear inflammatory cells within alveoli, and in walls of arteries, arterioles, bronchi, and bronchioles. Tissue factor was not detected in unaffected lung, liver, spleen, lymph node or kidney tissue. Administration of Escherichia coli endotoxin intravenously resulted in tissue factor expression in lung, spleen, and lymph node tissue. Results of this study indicate that TF is expressed locally at sites of inflammation and systemically in endotoxemia. Therefore, TF may be involved in coagulation events associated with pneumonic pasteurellosis. 相似文献
39.
Abdul Rehman Zhang Deyuan Imran Hussain Muhammad Shahid Iqbal Yang Yang Luan Jingdong 《International Journal of Fruit Science》2018,18(4):445-461
ABSTRACTThe aim of this study was to use an econometric analysis to investigate the relationship between agricultural gross domestic product (AGDP) and variables such as apple, citrus, pears, grape and banana in Pakistan; data were explored from 1980 to 2015; we used time series data collected from secondary sources, including the Pakistan Bureau of Statistics, Statistical Year Books and the Economic Survey of Pakistan. Data were analyzed by using the Ordinary Least Square (OLS) method and Augmented Dickey Fuller (ADF) test, and results were interpreted by using the Johansen co-integration test. The machine learning technique was used to examine and predict the future agricultural productivity in Pakistan. We found that output of banana, citrus and pears had a positive and significant influence on AGDP, whereas apples and grapes had a negative but insignificant influence on AGDP. 相似文献
40.
Muhammad Dawood Shah Balu Alagar Venmathi Maran Mohammad Iqbal Fui Fui Ching Mohammad Tamrin Mohamad Lal Rafidah Binti Othman Rossita Shapawi 《Aquaculture Research》2020,51(1):215-221
Zeylanicobdella arugamensis (Annelida: Hirudinea), a marine parasitic leech, is currently affecting different species of cultured groupers, hybrid groupers, snappers and sea bass in Malaysia. Dillenia suffruticosa (Dilleniaceae), a medicinal plant found in Sabah, has been selected in our experiment to kill the leeches as a natural control method. The leech‐infested hybrid groupers were collected from aquaculture facilities, and the isolated leeches were challenged against methanol extract of D. suffruticosa leaves. The experiment was carried out using various concentrations of the extracts such as 25, 50 and 100 mg/ml. The methanol extract showed significant antiparasitic activity against Z. arugamensis with 100% mortality at a concentration of 100 mg/ml in 14.39 ± 3.75 min., followed by 50 and 25 mg/ml in 32.97 ± 9.29 and 41.77 ± 5.40 min., respectively. The phytochemical composition of the extract was determined using GC‐MS analysis to understand the nature of the principal compounds responsible for its antiparasitic properties. The leaves of D. suffruticosa demonstrated the presence of different bioactive compounds of various natures with varying percentages. Thus, it could be revealed that the methanol extract of D. suffruticosa mainly contains vital phytochemical compounds and showed an effective antiparasitic activity against the harmful leeches of hybrid groupers. 相似文献