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纳米技术在生物领域的广泛应用形成了纳米生物技术,而纳米药物载体和纳米中药的研究也成为近年来生物制药领域的研究热点之一。综述了纳米技术、纳米生物技术的定义,详细介绍了纳米药物载体和纳米中药的相关研究进展,以期为该技术的进一步应用提供理论依据。 相似文献
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纳米技术在畜牧业中的应用前景 总被引:1,自引:0,他引:1
纳米技术是指在纳米尺度(10-9m)下对物质进行制备、研究的工业化以及利用纳米尺度物质进行交叉研究和工业化的一门综合性技术体系,是20世纪80年代末逐渐发展起来的新兴科技领域。并随着扫描隧道显微镜(STM)、原子力显微镜(AFM)光摄技术等微观表征操纵技术的出现有了长足的发展。研究证实,当微粒进入纳米量级(1 ̄100nm)时,其本身有表面效应、小尺寸效应、量子效应和宏观隧道效应,以致纳米材料的光、热、电、磁等物理性质出现许多新奇的特性。纳米体系的庞大比表面,使键态严重失配,出现许多活性中心,表面台阶和粗糙度增加。表面出现非化学… 相似文献
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纳米技术是指在纳米尺度(10^-9m)下对物质进行制备、研究的工业化以及利用纳米尺度物质进行交叉研究和工业化的一门综合性技术体系.是20世纪80年代末逐渐发展起来的新兴科技领域。并随着扫描隧道显微镜(STM)、原子力显微镜(AFM)光摄技术等微观表征操纵技术的出现有了长足的发展。研究证实,当微粒进人纳米量级(1~100nm)时,其本身有表面效应、小尺寸效应、量子效应和宏观隧道效应,以致纳米材料的光、热、电、磁等物理性质出现许多新奇的特性。纳米体系的庞大比表面,使键态严重失配,出现许多活性中心,表面台阶和粗糙度增加。表面出现非化学平衡、 相似文献
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纳米技术是20世纪80年代新兴发展起来的核心信息技术,广泛应用于生命医学、光电化工等领域。纳米技术与寄生虫病的试剂仪器诊断、药物治疗及疫苗防控环节有机结合,全面应用于纳米金标检测试纸条、试剂盒和仪器设备、纳米载体靶向驱虫药物、新型纳米疫苗佐剂的研发制备等方面,深入渗透到医学领域并广泛应用到寄生虫学中。作者着眼于当前纳米技术在寄生虫学中的应用,重点阐述了其在寄生虫病的检测诊断、驱虫药物和疫苗佐剂中的应用情况,包括胶体金标记免疫亲和层析、微粒材料合成、生物传感等纳米技术在寄生虫病检测诊断中的应用,总结了新型纳米驱虫药物脂质载体、化学合成药、草本中药研发的进展,并对疫苗佐剂研发中的热点,如纳米脂质体、聚合物颗粒、细胞因子的相关进展进行了概述。本文旨在为纳米技术在寄生虫学中的深入应用和研究提供参考。 相似文献
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纳米是长度的度量单位,又称毫微米,即百万分之一毫米。目前,纳米技术已在多个行业得到了应用,如纳米物理学、纳米电子学、纳米生物学、纳米化学、纳米计量学和纳米加工学等。应用于药物学领域的纳米技术称为纳米药物学。纳米粒在药物学上的应用主要有纳米药物载体和纳米药物制剂2种。纳米药物的生产成本低、效率高、自动化程度高、规模大,而药物的作用也实现了器官靶向、高效和低毒等革命性的突破,并具有稳定性好、对胃肠刺激性小等优点。因此,纳米药物在国际工业领域以及医药领域均具有广阔的发展前景。阐述了纳米技术在医学领域的研究及应用。 相似文献
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A nuclear medicine facility constructed specifically for the application of a gamma camera system to the radioisotope imaging of bone, pulmonary circulation and ventilation in the horse is described. The gamma camera was previously used for human nuclear medicine, and a support for the gamma camera head was specifically designed for this work. Imaging protocols are suggested and the necessary materials for bone and lung studies are described. Images of bone and lung are shown and computer analysis of the data indicated. Imaging times are approximately 1 to 2 mins and typical bone and lung studies can be completed in 20 to 30 mins. 相似文献
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McDonald J 《Journal of veterinary medical education》2008,35(2):207-211
The American public is concerned about food safety, and there is a growing realization that we are ill equipped to handle major food-borne illness outbreaks and bioterrorism. Since veterinary medicine plays an important role in assuring the safety of our nation's food supply, we would like to present to veterinary and public health educators a newly emerging resource for food-safety educational materials. This article describes an integrative collaborative approach for the creation and dissemination of engaging food-safety teaching resources for veterinary faculty. This USDA-funded project, Design to Dissemination: Developing Materials and Repository for Integrative Veterinary Food Safety Education, involves expert teachers in diverse fields and from many veterinary schools. The purpose of the project is to create materials that teach students food safety from farm to fork, and it offers teachers clinically relevant teaching resources that are difficult to create or locate. The educational materials are being created as smaller "building blocks" of content, commonly referred to as "learning objects" (LOs), focused on individual learning objectives. These learning objects are placed in the Veterinary Food Safety Education Learning Object Repository, where they are catalogued, stored, and kept accessible and where faculty can search, evaluate, and download teaching materials to use in their courses. In this way the learning objects can be more easily shared and reused or repurposed for other courses and applications. With this article we hope to excite faculty in veterinary schools and public-health programs and encourage them to use the repository and participate in piloting the educational materials. 相似文献
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Communication is a core clinical skill of veterinary medicine and one that needs to be taught and learned to the same degree as other clinical skills. To provide this education and essential expertise, veterinary schools in many countries, especially including North America, the United Kingdom, and Australia, have begun to develop programs and communication curricula. Human medical education, however, has 30 years' experience in developing communication curricula, and is thus an excellent resource upon which veterinary educators can build and shape their own communication programs. This article describes a skills-based communication course that has been successfully implemented for veterinary medical education at Ontario Veterinary College (OVC) and was based on the University of Calgary Faculty of Medicine's well-established program. The Calgary-Cambridge Guides and supporting textbooks provide the scaffolding for teaching, learning, and evaluation in both programs. Resources such as space and materials to support the OVC program were also patterned after Calgary's program. Communication skills, and the methods for teaching and learning them, are equally applicable for the needs of both human medicine and veterinary medicine. The research evidence from human medicine is also very applicable for veterinary medicine and provides it the leverage it needs to move forward. With this extensive base available, veterinary medicine is in a position to move communication skills training forward rapidly. 相似文献
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本试验目的是探讨中药甜菜碱复方对处于高温环境中三黄鸡消化系统和免疫系统部分组织器官生长发育的影响。选择15日龄三黄鸡288只,随机分成8组。高温对照组仅喂基础日粮,中药Ⅰ、Ⅱ、Ⅲ组分别在基础日粮中添加0.4%、0.8%、1.2%的中药,中药甜菜碱Ⅳ、Ⅴ、Ⅵ组分别在基础日粮中添加0.4%中药+0.2%甜菜碱、0.8%中药+0.2%甜菜碱、1.2%中药+0.2%甜菜碱,甜菜碱组在基础日粮中仅添加0.2%甜菜碱。在42日龄、70日龄和98日龄时,每组随机选取4只(2公、2母),剖解,称量其消化系统和免疫系统部分组织器官重量,并固定,制片,显微镜下观察组织细胞变化。结果表明,与高温对照组相比,添加中药甜菜碱复方Ⅰ、Ⅱ、Ⅲ组三黄鸡的肌胃、胰腺和肾脏的重量在3个日龄段均显著(P〈0.05)增加,胸腺、脾脏和法氏囊重量显著(P〈0.05)或极显著(P〈0.01)增加;添加中药Ⅱ组和甜菜碱组仅胸腺、脾脏和法氏囊的重量显著增加(P〈0.05)。71-98日龄段,中药甜菜碱复方Ⅰ、Ⅱ、Ⅲ组,甜菜碱组,中药Ⅱ、Ⅲ组肝脏重量显著(P〈0.05)或极显著(P〈0.01)增加。中药、甜菜碱及复合添加剂对15-42日龄腺胃重量和15-70日龄肝脏重量的影响则不明显。组织学观察,高温对照组三黄鸡肝脏、胸腺、脾脏、法氏囊等器官造成不同程度的病理变化,而0.8%中药-0.2%甜菜碱复方组三黄鸡相应的组织器官则未见有明显的病理变化。这表明高温环境对三黄鸡消化系统和免疫系统某些组织器官产生了一定的损伤,添加中药甜菜碱复方可缓解其损伤,促进组织器官的生长发育。其中,以添加0.8%中药-0.2%甜菜碱复方抗高温应激的效果最好。 相似文献
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E J Noga 《Veterinary Clinics of North America: Small Animal Practice》1988,18(2):401-426
Biopsy and rapid postmortem techniques are simple to perform with commonly available instruments. Because the skin and gills are the target organs for so many infectious agents, biopsy is a very useful tool in pet fish medicine. The major requisite for successful diagnosis using biopsy materials is the ability to recognize different taxonomic groups of pathogens. Many of these pathogens may be present in clinically normal individuals, and their importance must be interpreted with other clinical findings. Rapid postmortem techniques can identify several common systemic diseases affecting pet fish. The usefulness of these procedures is highly dependent on the state of tissue preservation of the specimens presented. 相似文献