鸡传染性腔上囊病的防治

鸡传染性腔上囊病是一种由传染性法氏囊病毒引发的急性、接触传染性疾病,具有发病率高、死亡率低和传播途径广等特点.鸡传染性腔上囊病可感染不同品种的鸡,肉鸡的发病率高于蛋鸡,而且以3～6周龄雏鸡发病率最高.由于鸡传染性腔上囊病以法氏囊受损为主要临床特征,容易在高度易感鸡群中急性暴发,因此给养殖者带来较大的经济损失.本文从该病的发病原因、流行特点、临床症状、病理解剖、药物治疗和防治措施等方面进行了概述,供同行参考、交流与借鉴.     

高免卵黄液的制备及其口服对鸡传染性法氏囊病的防治效果

作者制备了传染性法氏囊病的高免卵黄液,并对其口服防治效果进行了研究。患有鸡传染性法氏囊病的600只上海土鸡经投用抗生素药物治疗4 d无效后,采用口服高免卵黄液（2 ml/只）进行治疗,每天口服2次。1 d后,有12只发生死亡,其余鸡只逐渐恢复正常（治愈率98%）。表明高免卵黄液对治疗鸡传染性法氏囊病有良好的临床效果,同时也反映出口服高免卵黄液是一种较好的免疫途径和方法。     

鸡传染性囊病指检诊断法的临床应用

鸡传染性囊病(IBD)又名鸡传染性腔上囊病。法氏囊是受这种病毒攻击的主要靶器官。根据病鸡法氏囊普遍肿大这一病变特征,在临床上利用指检法诊断、监测IBD,争取早期用高免卵黄液治疗,取得较满意的效果。本人自1992年8月～1993年5月用指检诊断法检查发现4群病鸡并进行治疗,现将情况报道如下。     

鸡传染性法氏囊病的防控

<正>鸡传染性囊病又称腔上囊炎,是由双股RNA病毒科双股RNA病毒属的传染性囊病病毒IBDV引起的雏鸡的一种急性、接触性、免疫抑制性传染病。临床表现为病鸡精神不振、厌食、腹泻、高度虚弱和免疫抑制。病理变化以腔上囊肿大、肌肉出血、肾脏损伤为特征。发病后常呈尖峰死亡,一     

麦收时节谨防鸡传染性法氏囊病

<正>鸡传染性法式囊病又称腔上囊炎,是由双股RNA病毒科双股RNA病毒属的传染性法式囊病病毒引起的雏鸡的一种急性、接触性、免疫抑制性传染病。临床表现为病鸡精神不振、厌食、腹泻、高度虚弱和免疫抑制。病理变化以腔上囊肿大、肌肉出血、肾脏损伤为特征。发病后常呈尖峰死亡,一般在发病的第3~4天出现死亡,5~7天达到死亡高峰,其发病率和致死率最高,之后逐渐减少。一、发病情况     

鸡传染性法氏囊病

传染性法氏囊病(IBD)又称传染性法氏囊炎、传染性腔上囊炎、甘博罗病、传染性囊病,是由传染性法氏囊病病毒(IBDV)引起的鸡的一种高度接触传染性疾病。     

法氏囊炎蛋黄抗体防制鸡传染性法氏囊病效果好

<正> 治疗和预防的效果鸡传染性法氏囊病是一种破坏鸡免疫中枢器官一法氏囊(也称腔上囊)的病毒性传染病。主要危害25—45日龄雏鸡。目前尚无有效的药物治疗。 1990年鸡传染性法氏囊病在全市大流行,海淀区有60％以上鸡场发生,在这如此严峻的情况下,我区在七个鸡场8.9万只鸡群中注射法氏囊炎高免蛋黄液(北京农大兽     

复方中草药治疗鸡传染性法氏囊病疗效观察

复方中草药治疗鸡传染性法氏囊病疗效观察蔡庆贤（宁波正大农业有限公司）鸡的传染性法氏囊病（ＩＢＤ），又称传染性腔上囊病或传染性囊病。于１９６２年首次发现。本病多发生于青年鸡的一种急性、高度接触性传染病｛对养鸡业构成严重的威胁。目前控制该病的方法主要是进...     

鸡传染性法氏囊病的流行特点及防制措施

鸡传染性法氏囊病又名腔上囊炎、传染性囊病,是由病毒引起一种急性高度接触性传染病,临床上以法氏囊肿大、肾脏损害为特征。     

囊炎康防治鸡传染性法氏囊病效果好

鸡传染性法氏囊病(IBD)发生面广,发病率高,并容易并发和继发其他传染病,对养禽业的发展造成极大威胁。对鸡传染性法氏囊病以往我们主要采用多种西药治疗,效果都不十分理想,采用IBD高免蛋黄液和高免血清治疗,又存在隐性垂直感染因子危害的弊端。从1998年开始我们应用纯中药制剂——囊炎康防治鸡传染性法氏囊病,收到较好的防治效果。现将有关情况总结如下,供同行参考。(一)临床症状鸡传染性法氏囊病(IBD)也称传染性囊病或腔上囊炎,是由传染性法氏囊病毒(IBDV)引起的一种幼鸡(青年鸡)急性接触性免疫抑制性传染病。该病主要特性是因免疫失…     

鸡贫血病—法氏囊病联合免疫母鸡后子代雏鸡免疫器官T细胞和抗体生成细胞数量的动态变化

对鸡传染性贫血病（CIA）－传染性法氏囊病（IBD）联合免疫母鸡后的子代雏鸡免疫器官的免疫学化变化进行了研究。结果发现,混合感染CIAV、IBDV雏鸡免疫器官T细胞和IgG,IgM,IgA抗体生成细胞数量在27日龄内明显未免疫对照组、联合免疫组和联合免疫攻毒组,表明感染CIAV、IBDV的雏鸡全身免疫功能显著下降,CAI－IBD联合免疫母鸡后,子代雏鸡T细胞胞和IgG,IgM,IgA抗体生成细胞数量在27日龄内,较未免疫对照组明显增加,表明CIA－IBD联合免疫母鸡可使子代雏鸡免疫器官的免疫功能增强,能抵御强毒攻击。     

The use in practice of inactivated oil emulsion vaccine against infectious bursal disease in broiler breeders and its influence on the progeny: a comparative field trial

Field trials were conducted to establish the effect of the use of an inactivated oil emulsion vaccine against Infectious Bursal Disease (IBD OEV) in broiler breeder hens, and its effects on their progeny. The performance of 18 broiler flocks, which were the progeny of the IBD OEV vaccinated breeder hens, but which were not vaccinated with a live vaccine against IBD, was equal to that of broiler flocks which were vaccinated with a live IBD vaccine and originated from parent stock that had been vaccinated only against IBD with a live vaccine. In none of the 18 flocks, progeny of IBD OEV vaccinated parents, was IBD diagnosed. In a second stage, 15 broiler flocks were included in the trial: these were derived partly from IBD OEV vaccinated parents, and partly from parents that received only live IBD vaccine at 8-10 days of age. No cases of IBD occurred and all flocks were positive for IBD precipitins at slaughter age. Vaccination with a live vaccine against IBD at the age of 8-10 days had no influence on NCD antibody development after a NCD vaccination at 7 days. No immunosuppressive effect from this type of live live IBD vaccine could be determined under field conditions.     

雏鸡传染性法氏囊病的发病机理及鉴别诊断

雏鸡传染性法氏囊病(Infectious Bursal Disease,IBD)一直是危害我国养鸡业最严重的传染病之一,给养鸡业常造成巨大的经济损失和困扰,在鸡生产中越来越被给予重视。介绍了IBD的病原特点及其致病机理,详细阐述了IBD的鉴别诊断方法,为广大兽医工作者和养殖户提供参考。     

鸡新城疫、传染性支气管炎、传染性法氏囊病三联弱毒疫苗的试制

用同胚培养的鸡新城疫Lasota株和传染性支气管炎H120（或H52）株以及用鸡胚成纤维细胞增殖的传染性法氏囊弱毒株以适当比例混合为抗原,用蔗糖脱脂乳作保护剂,经真空冷冻干燥制成三联弱毒疫苗。通过三批疫苗室内外各项指标的测试,表明该三联疫苗安全性能可靠,免疫效果确实,使用方法简便。在实验室进行的物理性状检验、无茵检验、支原体检验、剩余水分检验、真空度检查均符合国家标准;用10倍大剂量接种15日龄雏鸡无不良反应;以常规量颈部皮下接种免疫后,7d产生免疫力,免疫后14d抗鸡新城疫、鸡传染性支气管炎、鸡传染性法氏囊病三株强毒攻击的保护率均为,100％。对15日龄雏鸡首免,其免疫期至少为30d,在-25℃保存期为1年。     

Dietary supplementation with Withania somnifera root powder ameliorates experimentally induced Infectious Bursal Disease in chicken

Tropical Animal Health and Production - Infectious Bursal Disease (IBD) is an economically important, immunosuppressive viral disease of chicken. Withania somnifera, a well-known Indian medicinal...     

外源病毒检验用抗鸡传染性法氏囊病病毒特异性血清的制备与检定

为制备外源病毒检验用抗鸡传染性法氏囊病病毒(Infectious Bursal Disease Virus,IBDV)的特异性血清,对300只3~4周龄的SPF鸡进行了基础免疫和加强免疫。最后一次免疫后21d采血并分离血清,血清经混合、分装、冷冻真空干燥后,对其进行了无菌检验、外源病毒检验、剩余水分测定、中和效价测定和特异性检验。结果表明,本研究制备的抗IBDV特异性血清无菌检验、外源病毒检验和剩余水分测定均符合《中华人民共和国兽药典》三部(二〇一〇年版)规定;血清中和效价为1:5747,与IBDV B87株毒种中和指数为104.3,与鸡新城疫病毒La Sota株、鸡传染性支气管炎病毒H120株、鸡传染性支气管炎病毒H52株、鸡传染性喉气管炎病毒、鸡痘病毒、禽呼肠孤病毒S1133株的中和指数均不大于10,通过AGP、ELISA、HI等试验确定血清中不含其他禽源外源病毒抗体。本研究为鸡传染性法氏囊病活疫苗或毒种的外源病毒检验提供了具有良好特异性和高效价的中和用血清。     

Investigations on live vaccines against infectious bursal disease of chicks

Summary Four live virus vaccines against Infectious Bursal Disease (IBD) were studied with regard to their safety, immune response and applicability. None of the vaccines caused clinical symptoms or had an adverse impact on bodyweight. Differences between these vaccins were observed in their effect on the Bursa/ Bodyweight Ratio and the severity of the microscopical lesions of the bursa Fabricii. The immunosuppressive effect of IBD vaccination at one day of age on the response to Newcastle disease vaccine applied was rather low. Three of the four vaccines induced antibodies associated with protection against challenge. Vaccination of SPF rearing chickens by drinking water at an age of 15 weeks produced an antibody response (Agar Gel Precipitin Test) whereas at an age of 23, 32 and 60 weeks it did not. Chickens of all age groups responded serologically to an intramusculair vaccination. A correlation was found between the immunological response and the effect of the vaccines on the bursa Fabricii.     

扶正解毒颗粒对人工感染鸡传染性法氏囊病的疗效观察

为评价扶正解毒颗粒的临床治疗效果,试验设扶正解毒颗粒低、中和高剂量组、扶正解毒散对照组、黄芪多糖对照组(黄芪多糖口服液)、阳性对照组(攻毒不给药)、阴性对照组(不攻毒不给药)。结果显示,扶正解毒颗粒低、高剂量组鸡成活率显著高于阳性对照组(P0.05);扶正解毒颗粒中、高剂量组相对增重率显著高于阳性对照组(P0.05);扶正解毒颗粒各剂量组免疫器官指数均显著高于阳性对照组(P0.05);扶正解毒颗粒各剂量组病变指数均极显著低于阳性对照组(P0.01);扶正解毒颗粒各剂量组法氏囊病毒含量均低于扶正解毒散对照组和黄芪多糖对照组。结果表明,扶正解毒颗粒对治疗鸡传染性法氏囊病有效,为其临床应用提供科学依据。     

鸡传染性法氏囊病细胞毒的浓缩粗提

应用聚乙二醇（ＰＥＧ６０００）沉淀法浓缩粗提鸡传染性法氏囊病病毒（ＩＢＤＶ）细胞毒,经毒价和紫外光ＯＤ值测定,浓缩病毒的毒价较浓缩前平均提高１个滴度;浓缩液中病毒含量及纯度是浓缩前的６倍以上。浓缩病毒与ＩＢＤ阳性血清和ＩＢＤ高免卵黄抗体ＩｇＹ琼扩反应呈弱阳性。加氯仿离心去除细胞杂蛋白后用ＰＥＧ沉淀ＩＢＤＶ细胞毒的方法,简便可行。     

Investigations on live vaccines against infectious bursal disease of chicks

Summary

Four live virus vaccines against Infectious Bursal Disease (IBD) were studied with regard to their safety, immune response and applicability. None of the vaccines caused clinical symptoms or had an adverse impact on bodyweight. Differences between these vaccins were observed in their effect on the Bursa/ Bodyweight Ratio and the severity of the microscopical lesions of the bursa Fabricii. The immunosuppressive effect of IBD vaccination at one day of age on the response to Newcastle disease vaccine applied was rather low.

Three of the four vaccines induced antibodies associated with protection against challenge. Vaccination of SPF rearing chickens by drinking water at an age of 15 weeks produced an antibody response (Agar Gel Precipitin Test) whereas at an age of 23, 32 and 60 weeks it did not. Chickens of all age groups responded serologically to an intramusculair vaccination.

A correlation was found between the immunological response and the effect of the vaccines on the bursa Fabricii.