牛多头蚴孢囊的摘除术

1 临床症状 牛多头蚴病是由寄生于犬、狼、狐狸等肉食动物小肠里多头绦虫的幼虫（脑多头蚴）寄生于牛的脑部所引起的绦虫蚴病，俗称脑包虫病。因能引起患畜明显的转圈症状，又称为转圈病。     

羊场暴发脑包虫病的诊治与防控

绵羊脑包虫病是由多头带绦虫（Taenia multiceps）的中绦期幼虫——脑多头蚴（Coenurus cerebralis）引起的一种严重危害羔羊的寄生虫病。脑多头蚴主要寄生于牛羊等反刍动物的脑和脊髓中,病畜出现一系列神经症状,最终导致死亡。介绍绵羊脑包虫病的病例情况、临床症状、病理剖解变化、诊断、手术治疗,分析发病原因,提出了针对脑包虫病的综合防控措施。     

我用这种方法治疗羊脑多头蚴

<正> 脑多头蚴(脑包虫)病是由多头绦虫——多头蚴寄生在羊的脑、脊髓内引起脑炎、脑膜炎及一系列神经症状,甚至使羊死亡的一种严重寄生虫病。民间俗称“转圈疯、回旋病”。脑多头蚴成虫一般寄生于犬、狼、狐等肉食动物的小肠内,并多见于犬经常活动的地方。1 发病情况某养殖户饲养的波尔山羊中有一只突然发病,神经症状明显。曾按脑膜炎进行治疗,用青霉素和磺胺嘧啶等药物治疗,效     

牛、羊脑多头蚴病的诊断与防治

脑多头蚴病是由寄生于狗、狼等肉食兽小肠里多头绦虫的幼虫（脑多头蚴）寄生于牛、羊的脑部所引起的绦虫蚴病,俗称脑包虫病。因为能引起患畜明显的转圈症状,又称为转圈病或旋回病。     

羊脑多头蚴病的防治

脑多头蚴病,俗称“脑包虫病”,是由多头绦虫的蚴虫寄生于羊的脑、脊髓内引起脑炎、脑膜炎及一系列神经症状、甚至引起死亡的寄生虫病。1病原     

山羊脑多头蚴病的药物治疗探寻

脑多头蚴病为牛羊养殖期间多见易发的寄生虫疾病,具有发病高、治愈难、人畜共患等特点,此病危害大严重威胁养羊产业的健康可持续发展。本着健康养殖、科学控病的要求,文章介绍脑多头蚴病,概述山羊脑多头蚴病的诊断要点,就临床用药建议作总结性论述,要点性知识以供参考和借鉴。     

多头蚴病的防治体会

多头蚴病（俗称脑包虫病）,对畜牧业生产危害很大。近年来我站在参加海北州棘球蚴病综合防治工作时,笔者采用手术和药物治疗多头蚴病,收到了一定的效果,现报告如下：１寄生部位与形状：多头蚴病是由多头绦虫的蚴虫寄生在羊、牛等的大脑（偶尔也寄生于延脑和脊髓）所引...     

牛、羊脑多头蚴病的症状及诊治

脑多头蚴病是由寄生于狗、狼等肉食动物小肠里多头绦虫的幼虫（脑多头蚴）寄生于牛、羊的脑部所引起的绦虫蚴病,俗称脑包虫病。患畜有明显的转圈症状,又称为转圈病或旋回病,人亦可感染。     

1例犊牦牛脑多头蚴病的手术治疗

脑多头蚴病是由寄生于狗、狼等肉食动物小肠内的多头绦虫的幼虫(脑多头蚴)寄生于牛、羊的脑部所引起的一种绦虫蚴病,俗称"脑包虫病"。2012年10月中旬,一头留作种用的犊牦牛出现精神沉郁、体温升高至41℃、脉搏和呼吸加快等症状,并出现流涎、磨牙、斜视、头颈弯向一侧等神经症状,综合诊断为脑多头蚴病,对其进行了手术治疗,7d后患犊康复。     

羊多头蚴的诊断与治疗

羊多头蚴病是由于多头带绦虫的幼虫即脑多头蚴寄生在羊的脑内,引起神经症状,甚至死亡的一种寄生虫病。1病原脑多头蚴,又称为脑包虫,属于绦虫类,是多头带绦虫的幼虫,呈现囊泡状,有的呈现豌豆粒大小,随着长到鸡蛋大小,囊内可以有一百多个原头蚴,一般有芝麻大小,原头蚴直径2-3mm。寄生在羊的脑内,是羊发生疾病的源头。     

Acute coenurosis of dairy sheep from 11 flocks in Greece

Abstract

CASE HISTORY: A syndrome of acute neurological dysfunction with increased mortality was observed in lambs of 10 dairy sheep flocks and adult animals in one flock in Central and Northern Greece. Each farmer completed a questionnaire regarding the management and feeding of their flocks. In seven of the 11 flocks the affected animals were grazing pasture, while in the remaining four flocks (5, 8, 9, 10) the animals were fed alfalfa hay (Medicago sativa) and concentrates indoors. A follow-up study of the affected flocks was conducted during the next 12 months.

CLINICAL FINDINGS: Of 42 sheep with acute coenurosis that were examined, the most prominent neurological abnormalities were ataxia, depression, blindness, scoliosis, coma and dysmetria. Except for the four sheep that were comatose, all other animals had normal body temperatures and their appetites remained normal or were slightly decreased. Haematological findings of 15 examined sheep were within normal limits. The affected sheep were subject to euthanasia. A histopathological examination was performed in 13 cases. Faecal samples from dogs associated with these flocks were negative for taeniid infections. During the following 12 months cases of chronic coenurosis in these flocks were observed.

PATHOLOGICAL FINDINGS: In the 42 animals that were necropsied, the main gross findings were cystic formations between 0.5–1 cm in diameter with translucent walls that were seen lying free on the leptomeninges or partly penetrating the brain tissue, sterile microabscecess and brain necrosis. Histopathological evaluation of tissue sections of 13 brains showed multifocal purulent or pyogranulomatous meningoencephalitis, accompanied by eosinophilic infiltrations. No bacteria were isolated following bacterial culture of brain tissue Parasitological examination of the cysts from five cases revealed whitish specks on the transparent cyst wall and germination membrane representing the scolices.

DIAGNOSIS: Acute coenurosis was diagnosed in all cases studied.

CLINICAL RELEVANCE: Acute coenurosis can be one of the causes of acute encephalopathy mainly in lambs, but also in adult sheep. This condition is incurable, but can be controlled by changing the feeding regime. Cases of chronic coenurosis may be seen a few months later in the same flock.     

牦牛脑多头蚴病药物治疗试验

用丙硫咪唑和吡喹酮两种驱虫药物,采用"药物增量法"和"药物联合法"对24头具有明显临床症状的脑多头蚴病例牦牛进行不同剂量治疗试验.结果表明,吡喹酮增量法治疗后症状消失时间最短,为8.5 d;丙硫咪唑增量法有效率和治愈率均为100%,吡喹酮增量法的有效率80%,治愈率70%;丙硫咪唑和吡喹酮联合法的有效率67%,治愈率50%.对照组10头脑多头蚴病牦牛均在不同时间内死亡.     

动物脑多头蚴病研究进展

脑多头蚴病是由多头绦虫的幼虫寄生于家畜所引起的疾病,人也可感染,但相对较少。该病通常对动物是致命的,给世界许多地区的养殖业造成了巨大的经济损失。论文主要介绍了不同药物对该病的疗效,以及脑多头蚴不同抗原成分免疫原性、分子分类和相关抗原基因的研究进展。     

Cloning and Prokaryotic Expression of Protein Kinase A Catalytic Subunit Gene from Taenia multiceps

To study the potential of protein kinase A catalytic subunit of Taenia multiceps (TmPKA-C) gene as a diagnostic antigen, the TmPKA-C gene was amplified by RT-PCR from the total RNA of Taenia multiceps. The TmPKA-C gene fragment was ligated into prokaryotic expression vector pET-30a and transformed into Escherichia coli Transetta (DE3) strain, then the reactonogenicity of recombinant TmPKA-C protein was analyzed by Western blotting and indirect ELISA. The open reading frame of TmPKA-C gene was 1 032 bp, encoding 343 amino acids. The expression product of TmPKA-C gene mainly existed in the form of inclusion body, and the molecular weight of recombinant protein was about 42 ku. Western blotting analysis showed that the recombinant protein could react specifically with the sera from naturally infected sheep with coenurosis, and it could also have specific reaction with the sera of artificial infected sheep with coenurosis. The indirect ELISA analysis showed that the sera from the coenurosis of sheep could react specifically with the recombinant protein. These results proved that the recombinant protein had good reactionogenicity. This study laid a foundation for the search of new diagnostic antigens for coenurosis of sheep.     

多头带绦虫蛋白激酶A催化亚基基因的克隆及原核表达

为鉴定多头带绦虫蛋白激酶A催化亚基（TmPKA-C）基因作为诊断抗原的潜能,本试验以多头带绦虫成虫RNA为模板,利用RT-PCR扩增TmPKA-C基因。将TmPKA-C基因片段连接至pET-30a原核表达载体进行原核表达,然后利用Western blotting和间接ELISA分析该蛋白的反应原性。结果表明,TmPKA-C基因开放阅读框的长度为1 032 bp,可编码343个氨基酸。TmPKA-C基因的表达产物主要以包涵体的形式存在,重组蛋白的分子质量大小约42 ku。Western blotting结果表明,该重组蛋白既能与自然感染脑多头蚴的绵羊血清发生特异性反应,又能与人工感染脑多头蚴不同时间段的绵羊血清发生特异性反应,表明该重组蛋白具有良好的反应原性。间接ELISA分析结果表明,脑多头蚴绵羊血清能与重组蛋白发生特异性反应,进一步证明该重组蛋白的反应原性良好。本研究为筛选脑多头蚴病诊断新抗原奠定了基础。     

Prevalence of Taenia multiceps in sheep in northern Jordan

From March 1996 to February 1997, slaughtered-sheeps' heads were examined for the metacestode of Taenia multiceps. Out of 451 sheep heads, only 12 (3%) were infested. All cysts but one were in the age group 0.5-2.5 years old, with prevalence of 10% (11 of 108). Eleven of 12 infested heads were found during the spring and autumn seasons. Out of 95 flocks involved in questionnaire survey unrelated to the abattoir survey, all the farmers reported the existence of the clinical signs known for coenurosis and described it in locally known names and diseases. Twenty-five of them had recent cases that were diagnosed by the veterinarian as coenurosis cases. Each flock reported one or two cases at the time of survey. A variety of clinical signs were reported from these cases (n = 42). These included circling (86%), head pressing (52%), blindness (29%) and paresis (40%). Coenurosis is a sheep-health problem and an important cause of sheep culling in Jordan.     

COMPUTED TOMOGRAPHIC FINDINGS IN OVINE COENUROSIS

Computed tomographic imaging was conducted in twenty ewes with cerebral coenurosis. CT imaging allowed precise evaluation of the size and location of the cyst, which appeared as a hypoattenuating structure with a mass effect. No meaningful correlation between clinical signs and the location of parasitic cyst was detected.     

羊脑包虫病CT、MRI影像特征

本研究旨在观察羊脑包虫病CT、MRI的特征性影像学表现。选择3只表现出脑包虫病典型症状的新疆细毛羊进行神经学检查及血常规、血清生化检查。对其中2只羊头部进行CT和MRI扫查。最后进行病理剖检,观察病理解剖变化。动物神经学检查发现动物出现眼球震颤,双侧眼睑反射、角膜反射减弱,动物的翻正反应、双侧独轮车反应存在异常;血常规和血清生化检查结果无明显异常;CT影像可见颅内数量不等囊性低密度影,内部CT值与脑脊液相近,边界清晰,有占位效应,囊壁分布大量点状中等到高密度的原头节影像,其余脑组织未见明显异常密度影像。MRI影像可见颅内数量不等囊性病灶,T1WI低信号,T2WI高信号,与脑脊液信号相近,可见沿囊壁分布大量点状T1等信号,T2低信号的原头节影像,病灶周围未见明显异常信号。病理剖检可见充满澄清囊液的寄生虫包囊,内含有数量不等的原头节。寄生虫包囊位置与影像学检查结果一致。结果说明羊脑包虫病具有特征性的CT和MRI影像学表现,影像学诊断方法可准确定位寄生虫包囊数量和位置,显示病灶累及周围组织的情况,有助于手术治疗计划的制定。     

A case of Multiceps gaigeri coenurosis in goat

A fatal case of Multiceps gaigeri coenurosis in a goat is described.