共查询到19条相似文献,搜索用时 203 毫秒
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为阐明睾酮在鹿角柄发生过程中的作用机理,本文对6头梅花鹿的生茸区骨膜和头部的非生茸区骨膜的睾酮特异结合进行了测定。所得结果为,正常、去势雄仔鹿的生茸区骨膜中都存在一定量的睾酮特异结合(分别为:正常,细胞质为29.32,细胞核为169.63;去势,细胞核为595.84。单位:fmol/mg蛋白),而非生茸区骨膜却未测到这种特异结合;雌鹿的测定结果为,除去势雌仔鹿生茸区骨膜具有一定量的睾酮特异结合(细胞核为223.21fmol/mg蛋白)外,其余生茸区和非生茸区均不存在睾酮特异结合。这些结果表明,雄仔鹿和去势雌仔鹿生茸区骨膜中可能存在着一定量的雄激素受体,这种骨膜在特定的生理条件下受睾酮的直接作用,是睾酮的靶组织。 相似文献
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1.1鹿茸的生长鹿茸和骨化的角统称为茸角,茸角着生于额骨的顶部。在正常情况下,茸角每年新生和脱落一次。茸角的新生和脱落都有一定的规律:茸角的脱落是在每年的春夏季节,这同时也是气温升高的季节,因此,茸角的脱落和新生与季节的变化是相互相承的。茸角的形成过程包括两个明显不同的阶段:一是从新茸萌发到茸皮脱落,此阶段上的茸角称为鹿茸;二是从茸皮脱落到骨角脱落,这阶段上的茸角称为鹿角。 相似文献
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1 鹿茸生长及其注意事项 1.1 鹿茸的生长 鹿茸和骨化的角统称为茸角,茸角着生于额骨的顶部.在正常情况下,茸角每年新生和脱落一次.茸角的新生和脱落都有一定的规律:茸角的脱落足在每年的春夏季节,这同时也是气温升高的季节,因此,茸角的脱落和新生与季节的变化是相互相承的. 相似文献
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《畜牧兽医学报》2017,(11)
旨在探究PI3K/AKT信号通路在鹿茸干细胞[包括生茸区骨膜(antlerogenic periosteum,AP)与角柄骨膜(pedicle periosteum,PP)细胞]中所发挥的作用,以期为揭示哺乳动物器官发生和完全再生机制提供借鉴。本研究通过MTT分析、细胞周期检测、细胞骨架染色等方法研究了抑制PI3K/AKT信号通路后对鹿茸干细胞增殖、细胞黏附、细胞周期、细胞骨架和促血管形成作用的影响。结果发现:1)相对于PP细胞,PI3K/AKT信号通路在调控AP细胞增殖和维持细胞骨架方面具有更为重要的作用;2)AP细胞条件培养液具有明显的促血管形成作用,PP细胞条件培养液不具有明显促进血管形成的作用。试验结果初步表明:相对于鹿茸再生,PI3K/AKT信号通路在鹿茸发生过程中的调控作用更为重要。 相似文献
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《黑龙江畜牧兽医》2016,(1)
鹿茸作为一种贵重中药,对人体有滋补作用,尤其在治疗虚弱、神经衰弱等方面效果更佳。鹿茸角是通过生茸干细胞的快速分裂和繁殖实现的,而这种鹿茸干细胞主要分布于鹿茸周围的骨膜组织中,随着鹿茸的逐渐长大,骨膜组织向间充质组织转化,而此时这之间的间充质细胞也仍然具有干细胞的特点,在体内也可以向软骨组织转化。而干细胞自身不仅具有进行复制、更新的能力,同时还具有在一定条件下"变身",即通过分化成为多功能细胞的能力。结果表明:间充质干细胞(MSC)是成体干细胞的一种,它的自我更新受自身内在基因和其所处微环境信号的共同调控。而其中的Notch、Wnt 2条有关发育调控的信号,则在这两种能力的调控过程中具有至关重要的作用。 相似文献
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Comparison of analgesic techniques for antler removal in halothane-anaesthetized red deer (Cervus elaphus): electroencephalographic responses 总被引:1,自引:0,他引:1
OBJECTIVE: To provide evidence for an analgesic effect of antler pedicle compression or lidocaine 'ring block' by comparing changes in median and spectral edge frequencies and total electroencephalographic (EEG) power during the application of each technique followed by antler removal. ANIMALS: Twenty-nine 2-year-old red deer (Cervus elaphus) stags weighing 106-131 kg each were used in this study. Stags were carrying immature growing antler suitable for commercial harvest. MATERIALS AND METHODS: Anaesthesia was induced using propofol (8.25 +/- 1.28 mg kg(-1)) and ketamine (2.18 +/- 0.15 mg kg(-1)) and maintained with halothane in oxygen. End-tidal halothane (Fe'HAL), expired CO(2) tension (Pe'CO(2)), SpO(2), EEG, ECG, and direct arterial blood pressures were recorded continuously. Respiratory rate and somatic responses were recorded at specific time points. After stabilization of anaesthesia (Fe'HAL was approximately 0.8%) baseline data were recorded. Stags were randomly allocated to one of three treatment groups; control, local anaesthesia, or compression band. One antler was removed 4 minutes after the application of treatment. Electroencephalographic responses to application of treatment and antler removal were analysed using area under the curve (AUC) analysis. Mean AUC was compared between groups using anova, and when significant differences were found, groups were compared post hoc with two-tailed t-tests. Significance levels were set at p = 0.05. RESULTS: Median frequency (F(50)) was increased during antler removal in the control group and during both application and antler removal in the compression group. In the lidocaine group, F(50) was decreased during both application and antler removal. Spectral edge frequency (F(95)) was increased during the antler removal period in the control group and during both application and antler removal in the compression group. In the lidocaine group, F(95) was decreased in the application time period. Total EEG power (P(tot)) was decreased in the removal period in the control group. In the compression group, P(tot) was decreased in the removal period. In the lidocaine group, P(tot) was decreased in the application period. There were no significant differences in EEG variables between antler removal in the control group and application of compression (p = 0.19-0.96). CONCLUSIONS: These data suggest that lidocaine 'ring block' of the antler pedicle provides adequate analgesia for velvet antler removal. The use of antler pedicle compression bands represents a noxious stimulus in its own right and is not as protective as lidocaine 'ring block' against the noxious stimulus of surgical antler removal. CLINICAL RELEVANCE: Compression of the antler pedicle has been recommended as an alternative to lidocaine 'ring block' for velvet antler removal. The results of this study suggest that antler pedicle compression is noxious. In addition, antler pedicle compression offers less effective analgesia than lidocaine 'ring block'. 相似文献
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D.R. Lang B.Agr.Sc M.S. Ph.D. 《New Zealand veterinary journal》2013,61(10):200-204
Dissection of the heads of 12 male Red deer revealed that the innervation and blood supply of the antler resembles those in the goat, in that the infratrochlear and zygomaticotemporal nerves supply the antler pedicle accompanied by two main branches of the superficial temporal artery and vein. Analgesia of the antler should be produced by injecting local anaesthetic solution both dorsal to the orbital rim and immediately caudal to the zygomatic process of the frontal bone. 相似文献
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天山马鹿数量性状相关的统计分析 总被引:1,自引:0,他引:1
探讨了凉泉天山马鹿上锯公鹿的体重、茸重、茸的鲜干比例性状与鹿年龄、茸重性状与体重 ,体重、体尺和茸尺性状与茸重的关系。结果表明 :在一定年龄段 ,这些数量性状除了体尺中角基距性状与茸重呈强负相关 (-r,P <0 0 1 )外 ,多呈极显著正相关 (P <0 0 1 ) ,少数呈显著正相关 (P <0 0 5 ) ,并建立了线性回归方程 ,为预测并比较天山马鹿各锯时的体重、茸重、体尺、茸尺和茸的鲜干比例水平及制审定其检测标准提供了科学依据。 相似文献
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OBJECTIVE: To compare changes in heart rate and arterial pressures resulting from compression of the antler pedicle or lidocaine 'ring block' and during subsequent antler removal during minimal halothane anaesthesia. ANIMALS: Twenty-nine 2-year-old red deer (Cervus elaphus) stags, weighing 106-131 kg and carrying immature growing antler suitable for commercial harvest were studied. MATERIALS AND METHODS: Anaesthesia was induced using intravenous propofol (median dose 8.0 mg kg(-1), range 5.2-11.0) and ketamine (median dose 2.2 mg kg(-1), range 1.9-2.4) and maintained using halothane in oxygen. End-tidal halothane concentration (Fe'HAL) end-tidal CO(2) tension (Pe'CO(2)), SpO(2), EEG, ECG, and direct systolic (SAP) mean (MAP) and diastolic (DAP) arterial pressures were recorded continuously. Respiratory rate and somatic responses were recorded. Baseline data were recorded once anaesthesia (Fe'HAL approximately 0.8%) was stable. Stags were randomly allocated to control, lidocaine 'ring block' or compression band treatment groups. One antler was removed 4 minutes after treatment. Cardiovascular responses to the application of analgesia and antler removal were analysed using a general estimates equation for repeated measures or area under the curve (AUC) analysis. Mean AUC was compared between groups using anova, and when significant differences were found, groups were compared post hoc with two-tailed t-tests. Somatic response data were compared with Fisher's exact chi-square test. A value of p < 0.05 was considered significant. RESULTS: Heart rate fell during observations in all groups with no significant differences between groups. Arterial pressures in the control and lidocaine groups during treatment and removal were not different from baseline values or from each other. Compression group pressures were significantly higher than baseline during both treatment and removal. Compression group DAP and MAP were significantly higher after antler removal than during treatment. In control and lidocaine groups, the AUC for SAP, DAP, and MAP over the combined baseline, treatment, and removal period did not differ. The compression group AUC for DAP and MAP were significantly greater over the experimental period than both the lidocaine group and control groups. Somatic responses occurred in one animal at lidocaine injection and three at compression application. Somatic responses occurred in eight control animals and two in the compression group at antler removal. More animals responded to antler removal in the control group than in the compression (p = 0.015) or lidocaine (p < 0.001) groups. CONCLUSIONS: Compression of the antler pedicle appears to be noxious. Pedicular compression is a less effective analgesic technique for antler removal compared to 'ring blocks' with lidocaine. CLINICAL RELEVANCE: This study suggests that lidocaine 'ring blocks' are the current technique of choice for antler removal in deer. 相似文献