| 口服喹烯酮代谢动力学研究 |
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| 引用本文： | 李剑勇,赵荣材,李金善,徐忠赞,柳军玺,薛飞群.口服喹烯酮代谢动力学研究[J].中国兽药杂志,2001,35(3):15-17. |
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| 作者姓名： | 李剑勇 赵荣材 李金善 徐忠赞 柳军玺 薛飞群 |
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| 作者单位： | 中国农业科学院兰州畜牧与兽药研究所,甘肃,兰州,730050 |
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| 摘 要： | 依据本实验建立的高效液相色谱法，测定了口服大剂量喹烯酮的肉鸡、仔猪血液浓度。结果表明：喹烯酮口服后，作用于消化道，不易被机体吸收，主要以原药形式排出体外，所以喹烯酮在机体内的残留极少。
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| 关 键 词： | 喹烯酮 饲料添加剂 代谢动力学 |
| 文章编号： | 1002-1280(2001)-03-0015-03 |
| 修稿时间： | 2000年7月5日 |
Study on the Pharmacokinetic in PIGS and Chickens of KXT in PO |
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| LI Jian-young,Zhao Rong-cai,LI Jing-shan,XU Zhong-zai,LIU Jun-xi,XUE Fei-qun.Study on the Pharmacokinetic in PIGS and Chickens of KXT in PO[J].Chinese Journal of Veterinary Drug,2001,35(3):15-17. |
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| Authors: | LI Jian-young Zhao Rong-cai LI Jing-shan XU Zhong-zai LIU Jun-xi XUE Fei-qun |
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| Abstract: | The experiment was to study the pharmacokinetic in pigs and chickens of KXT in PO. METHODS: HPLC determination method of KXT was first produced in the experiment. Plasma concentrations in pigs and chickens of KXT were measured after it was taken orally in supernormal dose. RESUTS: After KXT was taken, it had effect on digestive system. It was not easily adopted to their bloods and mainly excreted in formal type. CONCLUSIONS: The residues of KXT in pigs and chickens is very low. |
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| Keywords: | KXT \ pharmacokinetic \ HPLC |
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