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不同H_5亚型禽流感灭活苗对鸡H_5N_1株的免疫效力试验
引用本文:唐一鸣,刘金彪,张评浒,刘秀梵.不同H_5亚型禽流感灭活苗对鸡H_5N_1株的免疫效力试验[J].扬州大学学报(农业与生命科学版),2006(2).
作者姓名:唐一鸣  刘金彪  张评浒  刘秀梵
作者单位:扬州大学农业部畜禽传染病学重点开放实验室 江苏扬州225009
基金项目:国家“十五”科技攻关项目(2004BA519A02)
摘    要:采用H5N2和H5N1两种类型的禽流感(A I)油乳灭活疫苗免疫鸡群对高致病性A I流行株H5N1A IV的攻毒保护效力进行了比较。结果表明:在同等免疫剂量条件下,H5N2和H5N1油乳灭活苗对鸡群具有相似或同等的免疫效力,均能抵抗对高致病性A IH5N1流行株的攻击;A I母源抗体对灭活苗免疫具有一定的干扰作用。

关 键 词:禽流感    H5亚型油乳灭活苗  免疫  攻毒

Comparasion of protective efficacy of commercial chickens immunized with the different H_5 subtype inactived oil-emulsion vaccine to challenge of H_5N_1 AIV
TANG Yi-ming,LIU Jin-biao,ZHANG Ping-hu,LIU Xiu-fan.Comparasion of protective efficacy of commercial chickens immunized with the different H_5 subtype inactived oil-emulsion vaccine to challenge of H_5N_1 AIV[J].Journal of Yangzhou University:Agricultural and Life Science Edition,2006(2).
Authors:TANG Yi-ming  LIU Jin-biao  ZHANG Ping-hu  LIU Xiu-fan
Abstract:In this study,protective efficacy of commercial chickens at 14-day-old immunized with H_5N_2() and H_5N_1() subtype inactived oil-emulsion vaccine to the challenge of H_5N_1() AIV was evaluated.The results showed that the protective effects of flocks immunized with H_5N_1() and H_5N_2() was similar and presence of maternal antibody could interfere with chicken's active immunization.
Keywords:avian influenza  chicken  H_5() subtype vaccine  immunization  challenge
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