| 穿心莲中穿心莲内酯的提取工艺研究 |
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| 引用本文： | 尹秀莲,游庆红,王振华.穿心莲中穿心莲内酯的提取工艺研究[J].安徽农业科学,2009,37(15):6988-6989. |
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| 作者姓名： | 尹秀莲 游庆红 王振华 |
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| 作者单位： | 淮阴工学院生命科学与化学工程学院,江苏,淮安,223001 |
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| 摘 要： | 目的]对穿心莲中穿心莲内酯的提取工艺进行研究。方法]首先对不同提取溶剂进行考察，然后采用正交试验、单因素试验进行条件优化。结果]溶剂考察结果为以碱水、醇及水为溶剂时提取率分别为5．25‰、3．95‰、3．0‰；碱水提取时碱浓度为0．01％穿心莲内酯提取率最高，平均为5．64‰；醇提正交试验得出最佳工艺为10倍量85％乙醇提取2次，平均提取率为4．80‰。结论]从提取率及经济性考虑，碱水溶液提取比乙醇溶液提取较佳。
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| 关 键 词： | 穿心莲内酯 提取 HPLC |
Study on Extraction Process of Andrographolide from Andrographis paniculata |
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| Institution: | YIN Xiu-lian et al (School of Life Science and Chemical Engineering, Huaiyin Institute of Technology, Hnaian, Jiangsu 223001 ) |
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| Abstract: | Objective]The research aimed to study the optimum extraction process of andrographolide from Andrographis paniculata(Burm.f.)Nees.Method] Firstly,different extraction solvent were studied to choose the best extract solvent,then two kind solvents,ethanol and alkaline extraction processes were optimized by the orthogonal experiment and the single factor experiment respectively.Result] Solvent extraction study showed the extraction ratio of andrographolide by alkali,ethanol,water was 5.25‰,3.95‰,3.08‰ respectively.Results of different concentration of sodium carbonate water solution extraction experiment showed: 0.01% alkaline extraction could get the maximum extraction rate,the average extraction rate is 5.64‰.The best ethanol process was: adding 10 times of 85% ethanol,refluxing for 2 times,the average extraction rate was 4.80‰.Conclusion] Compared these two extract methods,the sodium carbonate extract was better. |
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| Keywords: | Andrographolide Extraction HPLC |
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