丙酸盐在反刍动物中的应用

丙酸盐是一类高效、安全的添加剂，具有防霉、防腐和治疗疾病等功能，广泛应用于饲料加工业。丙酸盐在瘤胃中可分解为丙酸和矿物元素，其中丙酸是其主要的有效成分。丙酸盐可促进瘤胃发育，参与血糖调节，维持能量平衡，因此，生产中丙酸盐可用于治疗酮病。当前，有关丙酸盐的试验大多还停留在瘤胃灌注阶段，体外试验集中在肝脏糖异生途径上，围绕能量代谢展开，而有关在生产性能和发酵水平的研究较少。随着短链脂肪酸在医学领域的深入探索，为其在畜牧业中的应用带来了新的契机，丙酸是否具有促进瘤胃发育、缓解炎症及增强免疫的能力有待进一步探究和验证。作者主要介绍了丙酸盐的代谢途径与作用机制，并结合生产性能和维持健康两方面阐述了丙酸盐在反刍动物营养上的应用，揭示了丙酸盐的潜在价值，以期为其在反刍动物领域的应用提供科学依据。

Research Progress on Propionate Application in Ruminant

Propionate is a kind of new,efficient and safe additive with the functions of anti-mildew,anticorrosion and treatment of diseases,which is widely used in feed processing industry. Propionate is decomposed into propionic acid and mineral elements in the rumen, and propionic acid is the main active ingredient. Propionate can promote rumen development,regulate blood glucose,maintain energy balance,therefore,it has been used to treat ketosis in practice production. At present,the propionate has been studied mostly at the rumen infusion stage,and in vitro experiments are focused on the liver gluconeogenesis pathway,which revolves around energy metabolism. But there are a few researches about the effects of propionate on production performance and fermentation. With the development of study of short chain fatty acids in the medical field,it brings a new opportunity for its development in husbandry. Whether propionate has the ability to promote rumen development, alleviate inflammation and enhance immunity needed to be further explored and verified. This paper mainly introduces the metabolic pathway and the mechanism of propionate and its application value in ruminant animal nutrition,combined with the production performance and maintain health,in order to reveal its potential value and provides scientific basis for its application in ruminant.