| 鸡Myogenin基因单核苷酸多态检测及群体遗传分析 |
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| 引用本文： | 王启贵,李辉,李宁,王宇祥,唐志权.鸡Myogenin基因单核苷酸多态检测及群体遗传分析[J].东北农业大学学报,2008,39(6). |
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| 作者姓名： | 王启贵 李辉 李宁 王宇祥 唐志权 |
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| 作者单位： | 1. 东北农业大学动物科学技术学院,哈尔滨,150030
2. 中国农业大学农业生物技术国家重点实验室,北京,100094 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)，东北农业大学校科研和教改项目 |
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| 摘 要： | 肌纤维在决定肌肉生长和肉质方面起主要作用,并受到MyoD基因家族的调控。该家族基因编码螺旋-环-螺旋蛋白。以鸡Myogenin基因为候选基因,通过PCR-SSCP分析该基因5′调控区的变异。结果表明,在鸡Myogenin基因5′调控区存在3处SNPs,这些SNPs产生的不同基因型及等位基因在7个品种鸡间分布存在极显著的差异(P<0.001)。推测该基因的变异对鸡生长发育可能有一定的影响。
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| 关 键 词： | 鸡 Myogenin基因 单核苷酸多态 |
Detection of single nucleotide polymorphism of Myogenin gene and population genetic analysis in chicken |
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| WANG Qigui,LI Hui,LINing,WANG Yuxiang,TANG Zhiquan.Detection of single nucleotide polymorphism of Myogenin gene and population genetic analysis in chicken[J].Journal of Northeast Agricultural University,2008,39(6). |
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| Authors: | WANG Qigui LI Hui LINing WANG Yuxiang TANG Zhiquan |
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| Abstract: | Muscle fibers have an important effect on muscle growth and meat quality,and can be controlled by MyoD gene family which encodes helix-loop-helix proteins.In this paper,the chicken Myogenin gene was selected as candidate gene,and its 5′region was analyzed by PCR-SSCP.The results showed that three SNPs were detected within 5′flanking of the chicken Myogenin gene,and distribution of different genotypes and allele by the three SNPs had very significant difference on 7 breeds.So it is presumed that the variations of Myogenin gene 5′region have an effect on growth and development in chicken. |
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| Keywords: | chicken Myogenin gene SNPs |
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