| 蒲公英提取物对LPS激活小鼠腹腔巨噬细胞炎症因子分泌的影响 |
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| 引用本文： | 刘利本,平家奇,刘婧陶,张雪梅.蒲公英提取物对LPS激活小鼠腹腔巨噬细胞炎症因子分泌的影响[J].动物医学进展,2011,32(2):45-47. |
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| 作者姓名： | 刘利本 平家奇 刘婧陶 张雪梅 |
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| 作者单位： | 延边大学农学院动物医学系; |
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| 基金项目： | 国家自然基金项目(31060349) |
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| 摘 要： | 采用MTT法检测蒲公英提取物对LPS激活小鼠腹腔巨噬细胞的毒性作用,并应用ELISA法测定蒲公英提取物对脂多糖LPS激活小鼠腹腔巨噬细胞TNF-α、IL-6和IL-β的含量.结果表明,蒲公英提取物在≤1 mg/mL剂量范围内对巨噬细胞无细胞毒作用,对LPS刺激的小鼠腹腔巨噬细胞TNF-α,IL-6和IL-1β分泌具有明...
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| 关 键 词： | 蒲公英提取物 炎症因子 脂多糖 |
Effect of Dandelion Extract on Inflammatory Cytokine Secretions in LPS-stimulated Mouse Macrophages |
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| LIU Li-ben,PING Jia-qi,LIU Jing-tao,ZHANG Xue-mei.Effect of Dandelion Extract on Inflammatory Cytokine Secretions in LPS-stimulated Mouse Macrophages[J].Progress In Veterinary Medicine,2011,32(2):45-47. |
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| Authors: | LIU Li-ben PING Jia-qi LIU Jing-tao ZHANG Xue-mei |
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| Institution: | LIU Li-ben,PING Jia-qi,LIU Jing-tao,ZHANG Xue-mei(Department of Veterinary Medicine,Agricultural College of Yanbian University,Longjing,Jilin,133400,China) |
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| Abstract: | The cytotoxic activity of dandelion extract on lipopolysaccharide(LPS)-stimulated mouse macrophages was examined by using MTT methods,the infammatory cytokine secretions in LPS-stimulated macrophages were determined by ELSA method.The results showed that dandelion extract was not cytotoxic on LPS-stimulated macrophages in less than or equal to 1 mg/mL.The dandelion extract has obvious inhibitory effect on infammatory cytokine secretions in a dose-dependent manner in LPS-stimulated mouse macrophages. |
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| Keywords: | dandelion extract inflammatory factor LPS |
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