亚急性瘤胃酸中毒对反刍动物瘤胃生理功能及物质吸收转运的影响

畜牧业集约化养殖越来越普遍。为提高反刍动物生产性能,饲喂大量能量饲料,进而引发亚急性瘤胃酸中毒(SARA),导致动物采食量下降、畜产品产出降低以及动物发生炎症反应。近年研究表明,SARA会改变瘤胃生理状态,而瘤胃健康对反刍动物饲养至关重要。本文综述了反刍动物SARA状态下瘤胃生理生化过程变化,结合瘤胃发酵模式变化和瘤胃微生物的改变,重点阐述了SARA引起的瘤胃上皮细胞形态结构变化、屏障功能改变、瘤胃上皮细胞中物质转运及相关载体表达及其引发的瘤胃上皮细胞炎症通路,为更好指导反刍动物饲养及为瘤胃营养生理生化研究提供参考。

Effects of Subacute Ruminal Acidosis on Rumen Physiological Function and Substance Absorption and Transportation of Ruminants

Intensive animal husbandry is becoming more common.In order to improve the production performance of ruminants,a large amount of energy feed in a diet is fed,which in turn leads to subacute ruminal acidosis(SARA),resulting in a reduction in animal feed intake,a reduction in the production of animal by-products,and an inflammatory response in animals.Recent studies have shown that SARA can change the physiological state of the rumen,and rumen health is crucial for ruminant feeding.This article reviewed the changes of rumen physiological and biochemical process in the state of SARA,combined with changes in rumen fermentation patterns and in rumen flora,focusing on the changes of morphological structure,barrier function of rumen epithelial cells,substance transport in rumen epithelial cells and expression of related vectors and inflammatory pathways induced by SARA,which provided a reference for better guidance of ruminant feeding.