| 三聚氰胺时蛋鸡的急性生和蓄积毒性 |
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| 引用本文： | 赵才兵,朱连勤,朱风华,潘娜,陈甫,齐娟.三聚氰胺时蛋鸡的急性生和蓄积毒性[J].中国家禽,2011,33(3). |
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| 作者姓名： | 赵才兵 朱连勤 朱风华 潘娜 陈甫 齐娟 |
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| 作者单位： | 青岛农业大学动物科技学院,山东青岛,266109 |
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| 基金项目： | 青岛市公共领域科技支撑计划项目 |
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| 摘 要： | 通过2个试验,研究三聚氰胺经口染毒对蛋鸡的急性毒性和蓄积毒性.试验一,选择70只220日龄海兰褐蛋鸡随机分成7组,每组10只,蛋鸡一次口服三聚氰胺的剂量分别是944.7、1 306.7、1 807.4、2 500.1、3 458.0、4 783.1和6 616.0 mg/kg,研究三聚氰胺对蛋鸡的急性毒性.试验二,选择40只240日龄的海兰褐蛋随机分成对照组和试验组,每组20R,试验组蛋鸡每日口服三聚氰胺605.0 mg/kg,累积剂量至5LD50时结束试验,对照组口服等量淀粉,研究三聚氰胺对蛋鸡的蓄积毒性.试验结束后,对存活蛋鸡进行耐受性测定.结果表明,海兰褐蛋鸡口服三聚氰胺的LD50为2 419.9 mg/kg,95%可信限是2 017.0～2 903.4 mg/kg.蓄积系数K>5.三聚氰胺中毒存活鸡一次口服三聚氰胺2 419.9 mg/kg后,蛋鸡死亡率达8.3%;对照组蛋鸡初次口服三聚氰胺2 419.9 mg/kg后,死亡率达45%,二者差异显著(P<0.05).由此可见,三聚氰胺对蛋鸡具有低毒性、轻度蓄积的特点,蛋鸡对三聚氰胺具有较高的耐受性.
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| 关 键 词： | 三聚氰胺 蛋鸡 急性毒性 蓄积毒性 |
Acute and Accumulative Toxicity of Melamine in Layers |
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| ZHAO Caibing,ZHU Lianqin,ZHU Fenghua,PAN Na,CHEN Fu,Qi Juan.Acute and Accumulative Toxicity of Melamine in Layers[J].China Poultry,2011,33(3). |
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| Authors: | ZHAO Caibing ZHU Lianqin ZHU Fenghua PAN Na CHEN Fu Qi Juan |
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| Institution: | ZHAO Caibing,ZHU Lianqin,ZHU Fenghua,PAN Na,CHEN Fu,Qi Juan(College of Animal Science and Veterinary Medicine,Qingdao Agricultural University,Qingdao,Shandong 266109) |
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| Abstract: | Two trials were conducted to determine acute oral toxicity and accumulative toxicity of melamine in layers.Experiment 1 was acute oral toxicity test.Seventy Hy-line layers were divided randomly into seven groups which were orally administered with melamine 944.7,1 306.7,1 807.4,2 500.1,3 458.0,4 783.1 and 6 616.0 mg/kg respectively.Experiment 2 was accumulative toxicity test.Forty Hy-line layers were divided randomly into experimental and control groups.The layers of experimental group were orally administe... |
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| Keywords: | melamine layers acute toxicity accumulative toxicity |
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