The effect of dietary vitamin K (phylloquinone and menadione) levels on the vertebral formation in mummichog Fundulus heteroclitus |
| |
Authors: | Miho Udagawa |
| |
Institution: | National Research Institute of Fisheries Science, Yokohama, Kanagawa 236-8648, Japan |
| |
Abstract: | SUMMARY: The effect of different dosages of vitamin K, either as phylloquinone or menadione sodium bisulfite (MSB), on vertebrae formation during growth of mummichog Fundulus heteroclitus was investigated. Diets without vitamin K caused a significantly higher incidence of bone deformity in fish than diets supplemented with MSB or phylloquinone ( P < 0.01). These results indicate that vitamin K is essential for mummichog. A massive dose of MSB caused a high incidence of bone deformity compared with a lower dose, while an increased dose of phylloquinone brought about no significant difference in deformity incidence. The vertebral deformity was significantly higher ( P < 0.01) in fish fed a vitamin K-free diet (Control Group) and MSB-supplemented diet (Group MSB25) compared to fish fed a phylloquinone-supplemented diet (Group PK1). These results indicate that phylloquinone is more suitable than MSB as a vitamin K source in fish feed. |
| |
Keywords: | larvae menadione sodium bisulfite phylloquinone vertebral formation |
|
|