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| 镉对鲤遗传毒性和外周血细胞数量的影响 | |
| 引用本文： | 韩杰,许人骥,于慧慧,王水连,贾志磊,何勇琴.镉对鲤遗传毒性和外周血细胞数量的影响[J].淡水渔业,2010,40(1). |
| 作者姓名： | 韩杰 许人骥 于慧慧 王水连 贾志磊 何勇琴 |
| 作者单位： | 1. 洛阳师范学院生命科学系,河南洛阳,471022 2. 中国科学院大连化学物理研究所,辽宁大连,116023 3. 上海海洋大学食品学院,上海,201300 |
| 摘 要： | 将鲤(Cyprinus carpio)分别暴露于0.16、0.31、0.63、1.26 mg/L Cd2+溶液中,研究Cd2+对鲤外周血红细胞微核率、核异常率、红细胞和白细胞数量的影响,探讨Cd2+对鲤遗传毒性和外周血细胞数量影响的变化规律和趋势。结果显示:Cd2+对鲤红细胞微核率和核异常率的影响存在浓度-效应和时间-效应关系。与对照组相比,1.26 mg/L Cd2+组鲤在不同暴露时间的红细胞微核率和核异常率均极显著(P<0.01),核异常率在72 h显著(P<0.05)增加,72 h后表现为极显著(P<0.01)增加。Cd2+对鲤外周血淋巴细胞、单核细胞和嗜中性粒细胞比例的影响存在浓度-效应和时间-效应关系。相同Cd2+浓度下,鲤淋巴细胞比例随暴露时间增加先降低后上升,同一暴露时间淋巴细胞比例随Cd2+浓度增加而降低。相同Cd2+浓度下,鲤单核细胞和嗜中性粒细胞比例随暴露时间增加先升高后降低,同一暴露时间嗜中性粒细胞比例随Cd2+浓度增加而升高。研究表明,Cd2+对鲤具有遗传毒性效应,且随Cd2+浓度增加而增强。 |
| 关 键 词： | 镉 鲤(Cyprinus carpio) 微核 红细胞 白细胞 |
Effects of cadmium on the genetic toxicity and circulating blood corpuscle number in Cyprinus carpio |
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| HAN Jie,XU Ren-ji,YU Hui-hui,WANG Shui-lian,JIA Zhi-lei,HE Yong-qin.Effects of cadmium on the genetic toxicity and circulating blood corpuscle number in Cyprinus carpio[J].Freshwater Fisheries,2010,40(1). | |
| Authors: | HAN Jie XU Ren-ji YU Hui-hui WANG Shui-lian JIA Zhi-lei HE Yong-qin |
| Institution: | 1.Luoyang Normal College;Life Science department;Luoyang;Henan 471022;2.China Science Institute;Dalian Chemical and Physical Research Institute;Dalian;Liaoning 116023;3.College of Food;Shanghai Ocean University;Shanghai 201300 |
| Abstract: | Cyprinus carpio were exposed in different concentration of Cd2+solution to study the effect of Cadmium on the rate of micronuclei,the rate of abnormal nucleus and the number of erythrocyte and leucocyte in circulating blood and then discuss the influence on the genetic toxicity and the regularity of changing of blood corpuscle number.The trial showed that:The effects of Cd2+ on the rate of micronuclei and nuclear abnormalites had the relationship of concentration-effect and time-effect.They were all signifi... |
| Keywords: | Cadmium carp(Cyprinus carpio) mieronuclei erythrocyte leucocyte |
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