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从患皮肤病犬患病部位分离出1株真菌,对其培养特性、形态特征、致病性等生物学特性以及核糖体转录间隔区(rDNA-ITS)的分子特征进行研究.结果表明,该分离株具有曲霉菌的典型菌落和形态特征;经皮肤和腹腔接种途径感染免疫抑制小鼠,均出现与自然感染病例相似的皮肤病变;基于rDNA-ITS序列的分子鉴定证实该分离株为黑曲霉菌. 相似文献
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Nodular diseases 总被引:1,自引:1,他引:0
《Veterinary dermatology》2000,11(3):179-186
The development of a nodule is a fairly common reaction pattern in the skin and subcutaneous tissues of the horse. In many such nodules, the inciting aetiologic agent or antigen is unknown, but in some equine cases there is significant evidence for insect bite origin. The pathogenesis of some equine nodular diseases appears to involve marked collagen degeneration which varies from hyalinization to lysis and can become mineralized. The exact role the lytic collagen has in the pathogenesis of these lesions is still unknown. Vascular changes may be present in some entities. Other nodules may be caused by or complicated by the larva of Habronema spp. The clinical or histological entities outlined in this section include the collagenolytic granuloma, axillary nodular necrosis, unilateral papular dermatosis and cutaneous habronemiasis. 相似文献
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目的寻找有效防治犬蠕形螨和真菌混合感染性皮肤病药物。方法选取癣螨净888注射液进行稳定性、安全性和597条病犬临床药效试验,并与传统药物伊维菌素等进行疗效比较。结果4℃避光条件下3年内药效不变,犬按0.1~0.2 mL/kg皮下注射,未见不良反应。临床药效试验表明,888注射液对病犬的治愈率为67.18%,其杀螨抑菌总有效力为93.5%,明显高于伊维菌素组和中药组。结论癣螨净888注射液为防治犬螨虫真菌性皮肤病提供了有效药剂。 相似文献
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A unilateral, linear, papular-pustular dermatosis is described in a young Brittany Spaniel dog. The dermatosis appeared to follow Blaschko's lines and extended from the left inguinal region to the medial aspect of the left metatarsal area. The predominant histological finding was an eosinophilic and neutrophilic pustular mural folliculitis with prominent acantholysis of infundibular epithelium. There was a rapid and long-lasting (> 15 months) resolution after oral administration of methylprednisolone (1.6 mg kg(-1)). 相似文献
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Six adult dogs were presented with an unusual bullous dermatosis affecting the glabrous skin of the ventral abdomen and medial thighs. Clinically, flaccid bullae were accompanied by erythema, ulceration, haemorrhage and hyperpigmentation in four of six dogs; the remaining two dogs had thin skin without grossly apparent bullae. Histologically, subepidermal bullae and clefting, vascular proliferation and dilatation (phlebectasia), and alteration in the density and staining of superficial dermal collagen were seen in all dogs. In all cases, corticosteroid-containing topical products had been applied to the affected areas prior to the development of the dermatosis; skin lesions resolved when topical corticosteroids were withdrawn. Follow-up biopsy of three dogs showed resolution of the previously abnormal collagen and subepidermal clefting. Residual lesions included phlebectasia, comedones and hyperpigmentation. The authors postulate that subepidermal clefting was due to local, corticosteroid-induced skin fragility. This is the first report, to our knowledge, of bullous skin disease in dogs resulting from topical corticosteroid therapy. 相似文献
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Dermatoses caused by infestations of immature Ixodes spp. on dogs and cats in Sydney, Australia 总被引:1,自引:1,他引:0
Infestations of larval and nymphal Ixodes spp. were identified in 16 dogs and 16 cats from several small animal clinics in Sydney. Cases occurred in late summer or autumn, peaking in February, and were seasonally recurrent in some individuals. Clinical signs of infestation included a papular dermatitis and irritation or pruritus that ranged from severe to mild or absent. The distribution of tick attachment tended to be cranial and ventral, with the face, legs, axillae and ventrum the most commonly affected sites. The estimated number of ticks in each infestation varied from less than 10 to more than 100. Basic morphological examination of ticks collected from affected animals was performed by attending veterinarians using light microscopy, and larvae and nymphs belonging to the Ixodes genus were identified. Ticks collected from 17 animals and submitted to the Department of Medical Entomology, Westmead Hospital were putatively identified as I. trichosuri (57%) and I. holocyclus (25%) larvae. Histopathological samples of attachment sites collected from three dogs and one cat were characterised by ticks attached in well-demarcated invaginations of the skin ('tick craters') associated with variable epidermal and/or dermal necrosis, focal eosinophilic intraspinous pustules, mild to marked eosinophilic and neutrophilic, superficial to deep, dermal perivascular to interstitial inflammation, and moderate to marked superficial dermal oedema and red cell extravasation. A range of topical acaricidal preparations, including fipronil and synthetic pyrethroids, were used for treatment. 相似文献
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Topical treatment of canine and feline pyoderma 总被引:1,自引:0,他引:1
ERIC GUAGUERE 《Veterinary dermatology》1996,7(3):145-151
Abstract This paper is a review of commonly used topical antibacterial medications: benzoyl peroxide, chlorhexidine, povidone iodine, ethyl lactate, triclosan, mupirocin, neomycin, polymyxin B, bacitracin and fusidic acid. Included is a review of the pharmacokinetics, modes of action, adverse effects and clinical uses in veterinary dermatology. General recommendations for topical antibacterial therapy are presented. Résumé— Cet article est une revue des topiques antibactériens les plus couramment utilisés: peroxyde de benzoyle, chlorhexidine, povidone iodée, lactate d'éthyle, triclosan, mupirocine, néomycine, polymyxine B, bacitracine et acide fucidique. Il inclut notamment une revue des pharmacocinétiques, des modes d'action, des effets secondaires et des indications thérapeutiques de ces produits en dermatologie vétérinaire. Les indications générales du traitement topique antibactérien sont présentées. [Guaguere, E. Topical treatment of canine and feline pyoderma. (Traitement topique des pyodermites canines et félines). Veterinary Dermatology 1996; 7 : 145–151.] Resumen Este articulo es una revisión de los productos tópicos antibacterianos más frecuentemente utilizados: peróxido de benzoilo, clorhexidina, povidona yodada, etillactato, triclosan, mupirocina, neomicina, polimixina B, bacitracina y ácido fusidico. Se incluye una revisión de la farmacocinética, mecanismos de acción, efectos colaterales y sus usos clínicos en dermatologia veterinaria. Se presentan recomendaciones generales para la terapia antibacteriana tópica. [Guaguere, E. Topical treatment of canine and feline pyoderma. (Tratamiento topico de la pioderma canina y felina). Veterinary Dermatology 1996; 7 : 145–151.] Zusammenfassung— Diese Veröffentlichung besteht in einer Übersicht von häufig verwendeten topischen antibakteriellen Arzneimitteln: Benzoylperoxid, Chlorhexidin, Povidon-Jod, Ethyllaktat, Triklosan, Mupirocin, Neomycin, Polymyxin B, Bacitracin und Fusidinsäure. Mit eingeschlossen ist eine Übersicht über Pharmakokinetik, Wirkungsweise, Nebenwirkungen und klinische Anwendung in der Veterinärdermatologie. Allgemeine Empfehlungen für die lokale antibakterielle Therapie werden dargestellt. [Guaguere, E. Topical treatment of canine and feline pyoderma (Lokale Behandlung von kaninen und felinen Pyodermien). Veterinary Dermatology 1996; 7 : 145–151.] 相似文献
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对来自湘桂地区6个宠物医院的48 127个确诊病例进行调查,对犬皮肤病的种类、发病率及其与年龄和季节的相关性进行分析。结果表明,皮肤病发病率为28.53%。在皮肤病中,脓皮病和疥螨最为常见,分别占28.03%和26.18%。皮肤病的发病率随着年龄增长而下降。不同季节流行的皮肤病种类也有区别,但各皮肤病在冬季发病率最低。 相似文献
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Hartley C Donaldson D Smith KC Henley W Lewis TW Blott S Mellersh C Barnett KC 《Veterinary ophthalmology》2012,15(5):315-326
The clinical presentation and progression (over 9 months to 13 years) of congenital keratoconjunctivitis sicca and ichthyosiform dermatosis (CKCSID) in the Cavalier King Charles spaniel dog are described for six new cases and six previously described cases. Cases presented with a congenitally abnormal (rough/curly) coat and signs of KCS from eyelid opening. Persistent scale along the dorsal spine and flanks with a harsh frizzy and alopecic coat was evident in the first few months of life. Ventral abdominal skin was hyperpigmented and hyperkeratinized in adulthood. Footpads were hyperkeratinized from young adulthood with nail growth abnormalities and intermittent sloughing. Long-term follow-up of cases (13/25) is described. Immunomodulatory/lacrimostimulant treatment had no statistically significant effect on Schirmer tear test results, although subjectively, this treatment reduced progression of the keratitis. Histopathological analysis of samples (skin/footpads/lacrimal glands/salivary glands) for three new cases was consistent with an ichthyosiform dermatosis, with no pathology of the salivary or lacrimal glands identified histologically. Pedigree analysis suggests the syndrome is inherited by an autosomal recessive mode. 相似文献