排序方式: 共有19条查询结果,搜索用时 17 毫秒
1.
Judith A. Hudson DVM PhD Susan T. Finn-Bodner DVM MS Joan R. Coates DVM Donald C. Sorjonen DVM MS Stephen T. Simpson DVM MS James C. Wright DVM PhD Jan E. Steiss DVM PhD Nancy R. Cox DVM PhD Dana M. Vaughn DVM PhD Starr C. Miller BS Scott A. Brown DVM PhD Phillip D. Garrett DVM MS 《Veterinary radiology & ultrasound》1995,36(6):542-547
Doppler ultrasonography of the spinal cord was performed in 34 normal, anesthetized dogs following hemilaminectomy. This study was part of an investigation to evaluate the efficacy of a 21-aminosteroid compound and high dose methylprednisolone for the treatment of spinal cord trauma. Grey-scale images of the canine spinal cord were similar to those described for the spinal cord of people. Doppler waveforms of intraparenchymal spinal arteries exhibited high end diastolic blood flow velocities, indicating low resistance to flow. Doppler values (mean ± SD) for arteries immediately ventrolateral to the central canal were: Peak Systolic Velocity = 5.78 ± 2.5 cm/sec, Minimum Diastolic Velocity = 3.5 ± 1.62 cm/sec, Mean Velocity = 4.45 ± 1.96 cm/sec, Minimum Diastolic Velocity = 3.5 ± 1.62 cm/sec, Mean Velocity = 4.45 ± 1.96 cm/sec, Systolic/Diastolic ratio = 169 ± 0.19, Pulsatility Index = 0.53 ± 0.09, and Resistance Index = 0.4 ± 0.06. 相似文献
2.
D C Sorjonen 《Veterinary Clinics of North America: Small Animal Practice》1992,22(4):951-964
Animals with meningomyelitis have clinical neurologic signs that typically range from paraspinal discomfort to tetraplegia; however, most affected animals also show evidence of multifocal CNS involvement with brain stem and cerebral cortical structures being affected most commonly. The cause, duration, and host response to the disease process will determine the clinical signs in individual animals. Confirmation of a specific causative agent is difficult, but CSF analysis and immunotesting of serum and CSF yield the most rewarding diagnostic results. Successful treatment is based on formulation of an appropriate and aggressive therapeutic regimen. In some diseases, no effective treatment is available, and some animals may develop permanent neurologic disabilities. 相似文献
3.
Jeryl C. Jones DVM PHD Judith A. Hudson DVM PhD Donald C. Sorjonen DVM MS Charles E. Hoffman CVT BS LATG Kyle G. Braund BVS MVS PhD James C. Wright DVM MS PhD Phillip D. Garrett DVM MS Jan E. Bartels DVM MS 《Veterinary radiology & ultrasound》1996,37(2):133-140
Intraoperative Doppler ultrasonography was used to measure the effects of four experimental nerve root compression treatments (central compression, central-plus-lateral compression, lateral compression, and compression release) on arterial blood flow velocities in the seventh lumbar spinal ganglion of three dogs. Graphed blood flow velocity changes (change = treatment value − pretreatment value) were below baseline during the first three compression treatments and above baseline following compression release. Mean blood flow velocity changes for both central-plus-lateral compression and lateral compression differed (p ≤ 0.05) from changes for central compression. Changes for central-plus-lateral compression did not differ (p > 0.05) from changes for lateral compression. Changes among the first three compression treatments differed (p ≤ 0.05) from changes for compression release. No histologic abnormalities were identified in compressed nerve tissues, compared to contralateral controls. These findings indicate that stenosis within the L7-S1 intervertebral foramen may cause ischemia of the L7 spinal ganglion in dogs. 相似文献
4.
D C Sorjonen N R Cox L J Swango 《Journal of the American Veterinary Medical Association》1989,195(7):977-980
Thirteen dogs with encephalomyelitis attributable to canine distemper virus infection were classified into 3 groups on the basis of histopathologic evidence of virus-induced lesions in CNS tissue. Analysis of data indicated a similarity within groups when arranged by age, clinical neurologic signs, and alterations in the CSF electrophoretic protein values. Comparison with results in dogs with experimentally induced canine distemper encephalomyelitis suggested that when grouped by age, CSF electrophoretic values are helpful in predicting the CNS histopathologic changes in dogs with naturally acquired canine distemper encephalomyelitis. 相似文献
5.
Lisa S. Klopp DVM M.S. John T. Hathcock DVM M.S. Donald C. Sorjonen DVM MS 《Veterinary radiology & ultrasound》2000,41(4):300-307
Premortem magnetic resonance imaging (MRI) was performed in two cats with brain stem abscessation confirmed post mortem by histology and recovery of multiple bacterial species. The MRI features of the abscesses were distinctive and included a thick and marked enhancement of the abscess capsule and extension of the lesion from a tympanic bulla in one cat. A focal area of increased signal intensity was present on T2-weighted images. A circumscribed area of decreased signal intensity was surrounded by a ring of increased signal intensity on precontrast T1-weighted images. A center of decreased signal intensity with a thick, markedly enhanced abscess capsule was observed on post contrast T1-weighted images. These findings are compared to the current experimental and clinical literature of brain abscess. The underlying pathogenesis of MRI features is reviewed. 相似文献
6.
Tapani Hirvonen Joni Orava Niko Penttinen Katri Luostarinen Markku Hauta-Kasari Mika Sorjonen Kai-Erik Peiponen 《Wood Science and Technology》2014,48(5):995-1003
In this study, a comprehensive spectral image database of Nordic sawn timbers for public use was measured. Economically significant Finnish wood species birch (Betula sp.), Norway spruce (Picea abies) and Scots pine (Pinus sylvestris) were chosen for inclusion in the database. The total of samples was 107 containing heartwood, sapwood, decayed wood, blue stain, mold, resin, early wood, late wood, knots, cracks, pith, reaction wood and bark. Board and crosscut samples were measured in frozen, melted and room-dried conditions. The reflectance of samples was measured over a 300- to 2,500-nm wavelength range. Additionally, the photoluminescence of samples excited by an ultraviolet B light source was measured. The spot size used was 250 μm with an 80 mm \(\times \) 200 mm imaging area, and produced all in all 44 million spectra. In this paper, examples of the possibilities of this spectral image database as a means of detection of the spatial distribution of aromatic lignin and the moisture content (MC) of nonfrozen timber were introduced and provided. From the results, it was found that it was possible to detect the lignin distribution from spectral images, and simple and robust methods for wood MC estimations were also introduced. 相似文献
7.
Total protein, albumin quota, and electrophoretic patterns in cerebrospinal fluid of dogs with central nervous system disorders 总被引:1,自引:0,他引:1
D C Sorjonen 《American journal of veterinary research》1987,48(2):301-305
Cerebrospinal fluid was analyzed for total protein, albumin quota, and electrophoretic patterns of albumin and alpha-, beta-, and gamma-globulins in 10 healthy dogs and 35 dogs with CNS disorders. Values obtained in healthy dogs were used to establish control data. Samples also were collected from dogs with neurologic diseases that were classified according to clinical and pathologic diagnosis as inflammation, neoplasm, and spinal cord compression. The albumin quota and total CSF albumin values were used as indicators of blood-brain barrier disturbance. Four patterns were observed on agarose electrophoresis that included intrathecal immunoglobulin production, intrathecal immunoglobulin production combined with blood-brain barrier disturbance, blood-brain barrier disturbance, and unaltered CSF. These patterns correlated with the observed clinical and pathologic conditions. Seemingly, agarose electrophoresis of CSF is a simple and reliable technique that aids in the diagnosis of CNS disorders of dogs. 相似文献
8.
William B. Thomas DVM MS Donald C. Sorjonen DVM MS Ronald O. Scheuler DVM Joe N. Kornegay DVM PhD 《Veterinary radiology & ultrasound》1996,37(5):345-350
Magnetic resonance imaging was performed in seven dogs with histopathologically-confirmed brain infarcts. The infarcts were non-hemorrhagic in four dogs and hemorrhagic in three dogs. Six dogs had single infarcts involving the cerebrum and one dog had multiple infarcts involving the cerebrum and brain stem. Non-hemorrhagic infarcts were typically wedge-shaped, hypointense on T1-weighted images, hyperintense on T2-weighted images, and did not enhance with gadolinium-DTPA. Hemorrhagic infarcts had mixed intensity on T1- and T2-weighted images, with variable patterns of enhancement. 相似文献
9.
Susan T. Finn-Bodner DVM MS Judith A. Hudson DVM PhD Joan R. Coates DVM Donald C. Sorjonen DVM MS Stephen T. Simpson DVM MS Nancy R. Cox DVM PhD James C. Wright DVM phD Phillip D. Garrett DVM MS Jan E. Steiss DVM phD Dana M. Vaughn PhD Starr C. Miller BS Scott A. Brown DVM PhD 《Veterinary radiology & ultrasound》1995,36(1):39-48
Prior to trauma, intraoperative ultrasound of the spinal canal in 31 normal dogs was performed through a hemilaminectomy in the left pedicle of L2. A ventral compressive model of spinal cord injury was performed as part of a clinical drug trial. Maximum ultrasonographic spinal cord diameter ranged from 4.9–7.2 mm (5.7 × 0.6). Significant positive correlation (p = 0.023, r = 0.49) was found between age and spinal cord diameter. The dura mater was a separate, well-defined, echogenic horizontal line in 28 (90%) dogs, dorsally, and in 29 (94%) dogs, ventrally. Cerebrospinal fluid was anechoic. Eighteen (58%) dogs had a well-defined anechoic dorsal subarachnoid space, whereas 22 (71%) had a well-defined ventral space. Pia mater was thin but strongly echogenic and covered spinal cord. Central canal was a double hyperechoic line in 17 (55%) dogs and a single-line in 14 (45%) dogs. A difference in the ultrasonographic appearance between gray and white matter was not seen. Epidural fat and connective tissue was a lobular echogenic material in the ventral epidural space. The periosteal-vertebral body interface was seen as a bright curvilinear echo with distal acoustic shadowing. Spinal cord parenchyma could be classified subjectively into four groups based upon ultrasonographic appearance. Spinal cord parenchyma had a uniform hypoechogenicity in 8 (27%) dogs (Group 1), subtle low level echoes in 7 (23%) dogs (Group 2), multiple clusters of defined echogenic foci in 12 (37%) dogs (Group 3), and multiple sharply-defined linear echoes in 4 (13%) dogs (Group 4). There was a significant relationship between pre-trauma ultrasonographic appearance of the spinal cord and histopathology 21 days after trauma. One (13%) dog in Group 1, 4 (57%) dogs in Group 2,10 (91%) dogs in Group 3, and 3 (75%) dogs in Group 4 had malacia on histological evaluation. Therefore, dogs with echogenic spinal cords or linear echoes within cord parenchyma were significantly more likely to develop malacia rather than Wallerian degeneration after induced spinal cord trauma (p = 0.002). Spinal cord echogenicity may indicate vascularity in a segment of spinal cord and might be prognostic following spinal cord trauma. No complications were found related to intraoperative ultrasound. Hematoma or fibrous tissue formation appeared to impede percutaneous ultrasound of the spinal cord in dogs re-evaluated forty-eight hours and one week after surgery. 相似文献
10.
eryl C. Jones DVM PhD Donald C. Sorjonen DVM MS Stephen T. Simpson DVM MS Joan R. Coates DVM MS Stephen D. Lenz DVM PhD John T. Hathcock DVM MS Michelle W. Agee MD PhD Jan E. Bartels DVM MS 《Veterinary radiology & ultrasound》1996,37(4):247-256
In a three-year prospective study, computed tomographic (CT) and surgical findings were compared for nine large breed dogs with lumbosacral stenosis. Surgically-excised tissue was examined histologically in seven dogs and additional necropsy evaluation was performed in one dog. The CT abnormalities observed at sites of confirmed cauda equina compression were: loss of epidural fat, increased soft tissue opacity, bulging of the intervertebral disc margin, spondylosis, thecal sac displacement, narrowed intervertebral foramen, narrowed vertebral canal, thickened articular process, articular process subluxation, articular process osteophyte, and telescoped sacral lamina. The CT characteristics of lumbosacral degenerative disease and discospondylitis were similar to those described in humans. In three dogs, CT findings at the site of cauda equina compression were consistent with congenital or developmental spinal stenosis, but the method of surgical exposure precluded confirmation. Epidural fibrosis (eight dogs) and multi-level CT abnormalities (six dogs) were identified but the cause(s) and significance were unknown. 相似文献