Effect of the route of administration on the mucosal and systemic immune responses to Lawsonia intracellularis vaccine in pigs

In an on‐farm study, 40 weaned piglets aged 3 weeks were vaccinated with Lawsonia intracellularis vaccine orally, IM or IP while a fourth group remained unvaccinated. All vaccinated animals showed increased serum levels of L. intracellularis‐specific IgG antibodies, but significantly elevated concentrations of specific IgG, IgA and cytokines were generated in ileal mucosal secretions from the orally and IP vaccinated pigs when examined at 17 days after vaccination.     

Thiamin deficiency in cats and dogs associated with feeding meat preserved with sulphur dioxide

Thiamin deficiency was diagnosed in cats and dogs being fed fresh minced meat, which contained sulphur dioxide as a preservative and less than 0.5 mg/kg thiamin. Thiamin in the meat and in added dietary ingredients, including a supplementary vitamin mixture, was destroyed by the sulphur dioxide.     

A case of canine myeloid neoplasia

A case of myeloid neoplasia is described in a dog showing signs of anaemia, depression, lethargy, anorexia and enlargement of the liver and spleen which were considered typical of the disease. Rare features of the case included infiltration of neoplastic cells in the bladder wall and a normal peripheral blood total white cell count.