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RANDI DREES SOPHIE E. DENNISON NICHOLAS S. KEULER TOBIAS SCHWARZ 《Veterinary radiology & ultrasound》2009,50(1):74-79
Computed tomography (CT) has been applied previously for assessment of canine spinal disease using a multitude of different technical imaging parameters. The purpose of this study was to establish an optimized imaging protocol for the cervical and lumbar canine spine using a single-detector-row helical CT unit. Thin slice thickness (1–2 mm), low pitch (axial scan mode, helical pitch <2), and medium-frequency image reconstruction algorithm significantly improved the visibility of the intervertebral disk and spinal cord. Tube current, helical reconstruction interval, and the use of an additional edge enhancement filter had no significant effect on the visibility of the intervertebral disk and spinal cord. There was also no interaction between the use of an additional edge enhancement filter and image reconstruction algorithm. Use of an additional edge enhancement filter introduced a double ring artifact in the periphery of the spinal canal lumen that did not correspond to the spinal cord or pachymeningeal margin. 相似文献
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RANDI DREES ALEX FRYDRYCHOWICZ SCOTT B. REEDER MARIE E. PINKERTON REBECCA JOHNSON 《Veterinary radiology & ultrasound》2011,52(5):507-515
Canine coronary artery angiography (CTA) was performed in four anesthetized healthy dogs using 64‐multidetector computed tomography. Esmolol, a β‐1 adrenergic receptor antagonist, and sodium nitroprusside, an arteriolar and venous dilator, were administered to enhance visualization of the coronary arteries by reducing heart rate and creating vasodilation. The left main coronary artery with its three main branches and the right coronary artery were visualized and subdivided in 13 segments for evaluation. Optimal reconstruction interval, expressed as percentage of the R‐to‐R interval, was determined at 5% in 2.9%, 35% in 1%, 75% in 21.2%, 85% in 43.3%, and 95% in 31.7% of the segments. Overall image quality was good in 41.3% of the segments and excellent in 14.4%. There was blur in 98.1%, motion in 17.3%, and stair step in 6.7% of the evaluated segments, but these artifacts did not interfere with anatomic depiction of the arteries. Cross‐sectional anatomy of the coronary arteries as evaluated from the coronary CTA agreed well with gross anatomic evaluation and published information. The use of esmolol did not lead to the target heart rate of 60–65 beats/min. Nitroprusside had no significant effect on visualized length or diameter of the coronary artery branches. Coronary CTA is useful for the anatomic depiction of coronary artery branches in the dog. 相似文献
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Hidetoshi NARA Miho INOUE-MURAYAMA Akiko KOSHIMURA Akinori SUGIYAMA Yuichi MURAYAMA Masami MAEJIMA Yuko UEDA Hideyuki ITO Ettore RANDI Heui-Soo KIM Ji-Hong HA Hitoshi KITAGAWA Yukari TAKEUCHI Yuji MORI Toshiroh IWASAKI Mitsuo MORITA Katuaki ÔTA Shin'ichi ITO 《Animal Science Journal》2005,76(1):81-86
Various dog breeds are remarkably different from each other not only in their sizes and shapes but also in behavioral traits, suggesting that some of these characteristics are under genetic control. However, little is known about genes related to behavioral traits in canine species. In humans, it has been reported that the dopamine receptor D4 gene (DRD4) includes polymorphism at several regions that relate to personality or psychiatric disorders. In an earlier study by the authors of the present study, the polymorphisms in canine DRD4 exon III and exon I regions were reported. In the present study, a novel polymorphism in canine DRD4 intron II was found based on a 17 base pair insertion/deletion, and the two alleles detected were named P (shorter allele) and Q (longer allele). The allelic distribution in 28 breeds of dog, including a total of 1114 unrelated individuals, were then investigated. Both P and Q alleles were detected in most of the breeds investigated; however, the frequencies of P and Q differed greatly between breeds. With respect to classification based on breed origin, P and Q alleles were frequent in Occidental and Oriental breeds, respectively. Furthermore, two subspecies of wolves, the ancestors of dogs, were analyzed for the comparison of allele frequencies with dogs, and the P allele was predominant in both European and Chinese wolves. 相似文献
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RANDI DREES ALEX FRYDRYCHOWICZ NICHOLAS S. KEULER SCOTT B. REEDER REBECCA JOHNSON 《Veterinary radiology & ultrasound》2011,52(4):362-367
Pulmonary angiography using 64‐multidetector‐row computed tomography (MDCT) was used to evaluate pulmonary artery anatomy, and determine the sensitivity of pulmonary artery segment visualization in four Beagle dogs using images reconstructed to 0.625 mm and retro‐reconstructed to 1.25 and 2.5 mm slice thickness. Morphologically, characteristic features included a focal narrowing in the right cranial pulmonary artery in all dogs, which should not be mistaken as stenosis. While the right cranial pulmonary artery divided into two equally sized branches that were tracked into the periphery of the lung lobe in all dogs, only a single left cranial (cranial portion) lobar artery was present. Compared with 1.25 and 2.5 mm retro‐reconstructions, 0.625 mm reconstructions allowed for detection of significantly (P≤0.05) more pulmonary artery segments and sharper depiction of vessel margins. Clinical applications such as prevalence and significance of diameter changes, and detection of pulmonary arterial thrombembolism on lobar and sublobar level, using pulmonary angiography with 64‐MDCT applying 0.625 mm reconstruction slice thickness remain to be established. 相似文献
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SOPHIE E. DENNISON RANDI DREES HELENA RYLANDER BRIAN S. YANDELL MILAN MILOVANCEV ROGER PETTIGREW TOBIAS SCHWARZ 《Veterinary radiology & ultrasound》2010,51(3):254-258
Forty‐six dogs with either cervical (C1–C5 or C6–T2) or thoracolumbar (T3–L3) acute myelopathy underwent prospective conventional computed tomography (CT), angiographic CT, myelography, and CT myelography. Findings were confirmed at either surgery or necropsy. Seventy‐eight percent of lesions were extradural, 11% were extradural with an intramedullary abnormality, 7% were intramedullary, 2% were intradural–extramedullary, and 2% had nerve root compression without spinal cord compression. Intervertebral disc herniation was the most frequent abnormality regardless of signalment or neurolocalization. Twenty‐one of 23 Hansen type I disc extrusions but none of the Hansen type II disc protrusions were mineralized. Two chondrodystrophic dogs had acute myelopathy attributable to extradural hemorrhage and subarachnoid cyst. CT myelography had the highest interobserver agreement, was the most sensitive technique for identification of compression, demonstrating lesions in 8% of dogs interpreted as normal from myelography and enabling localization and lateralization in 8% of lesions incompletely localized on myelography due to concurrent spinal cord swelling. None of the imaging techniques evaluated permitted definitive diagnosis of spinal cord infarction or meningomyelitis but myelography and CT myelography did rule out a surgical lesion in those cases. While conventional CT was adequate for the diagnosis and localization of mineralized Hansen type I disc extrusions in chondrodystrophic breeds, if no lesion was identified, plegia was present due to concurrent extradural compression and spinal cord swelling, or the dog was nonchondrodystrophic, CT myelography was often necessary for correct diagnosis. 相似文献
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