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Evaluation of a virtual pet visit system with live video streaming of patient images over the Internet in a companion animal intensive care unit in the Netherlands 下载免费PDF全文
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Long‐term follow‐up of renal function assessing serum cystatin C in dogs with diabetes mellitus or hyperadrenocorticism 下载免费PDF全文
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On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target 总被引:12,自引:0,他引:12
J A Kelly O Dideberg P Charlier J P Wery M Libert P C Moews J R Knox C Duez C Fraipont B Joris 《Science (New York, N.Y.)》1986,231(4744):1429-1431
Structural data are now available for comparing a penicillin target enzyme, the D-alanyl-D-alanine-peptidase from Streptomyces R61, with a penicillin-hydrolyzing enzyme, the beta-lactamase from Bacillus licheniformis 749/C. Although the two enzymes have distinct catalytic properties and lack relatedness in their overall amino acid sequences except near the active-site serine, the significant similarity found by x-ray crystallography in the spatial arrangement of the elements of secondary structure provides strong support for earlier hypotheses that beta-lactamases arose from penicillin-sensitive D-alanyl-D-alanine-peptidases involved in bacterial wall peptidoglycan metabolism. 相似文献
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Lin GY Robben JH Murrell JC Aspegrén J McKusick BC Hellebrekers LJ 《Veterinary anaesthesia and analgesia》2008,35(2):141-153
OBJECTIVE: To evaluate cardiovascular and respiratory effects and pharmacokinetics of a 24-hour intravenous constant rate infusion (CRI) of dexmedetomidine (DMED) during and after propofol (PRO) or isoflurane (ISO) anaesthesia in dogs. STUDY DESIGN: Prospective, randomized, cross-over study. ANIMALS: Ten healthy adult Beagles. METHODS: Instrumented dogs received a DMED-loading bolus (25 microg m(-2)) at time 0 followed by a 24-hour CRI (25 microg m(-2) hour(-1)), with PRO or ISO induction/maintenance of anaesthesia during the first 2 hours (PRO and ISO treatment groups, respectively). Cardiovascular, respiratory, blood gas, airway gas, serum chemistry variables and DMED plasma concentration data were collected at -15, 5, 15, 30, 45, 60, 90 and 120 minutes. A number of cardiorespiratory and tissue oxygenation variables were calculated from the above data. After the 2-hours of anaesthesia, heart and respiratory rates and electrocardiograms were recorded and DMED plasma concentrations were determined for up to 26 hours. RESULTS: Vasopressor effects and the decrease in heart rate (HR) and cardiac index induced by DMED were greater for PRO than ISO, but were within clinically acceptable ranges. Adequate oxygenation was maintained above the critical O(2) delivery level. The overall incidence of unfavourable arrhythmias was low and tended to vary inversely with HR. Mean DMED plasma concentration ranged from 0.23 to 0.47 ng mL(-1) for both groups during the 24-hour CRI with a mean elimination half-life of approximately 0.46 hour. CONCLUSION AND/CLINICAL RELEVANCE: DMED CRI resulted in typical alpha(2)-agonist induced haemodynamic changes with minimal respiratory effects, and appeared to be an efficacious adjunct during and after PRO or ISO anaesthesia in healthy dogs. 相似文献
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Matthias Vanmaercke Willem Maetens Jean Poesen Benediktas Jankauskas Genovaite Jankauskiene Gert Verstraeten Joris de Vente 《Journal of Soils and Sediments》2012,12(4):586-602
Purpose
This study aims to understand better the relationship between measured soil loss rates due to sheet and rill erosion (SL), predicted SL rates and measured catchment sediment yields (SY) in Europe. 相似文献7.
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C. Hamers E. Di Valentin C. Lecomte M. Lambot E. Joris B. Genicot P.‐P. Pastoret 《Zoonoses and public health》2000,47(10):721-726
Seven of nine colostrum‐deprived calves, free from infection with bovine virus diarrhoea virus (BVDV), were vaccinated with Rispoval? RS‐BVD on two occasions, 21 days apart, while the other two were kept as BVDV infection controls. The virus neutralizing (VN) serum antibodies induced by vaccination were tested for their ability to neutralize 18 European BVDV isolates, including laboratory reference strains and recent field isolates, both cytopathic and non‐cytopathic biotypes as well as genotypes I and II. The strains were isolated in Belgium, France, Germany and the United Kingdom. While there were large variations in the vaccine‐induced VN titres of the individual calves against all the strains, e.g. the titres against Osloss NCP, the European reference strain ranged from 1.7 to 6.7 (1 : log2), serum from each animal was capable of neutralizing between nine and all 18 of the strains tested. Nevertheless, from the results of this study, it can be concluded that in colostrum‐deprived BVDV seronegative calves, Rispoval? RS‐BVD can stimulate the production of VN antibodies capable of neutralizing a wide range of antigenically diverse European isolates of BVDV, including genotypes I and II. 相似文献
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Stany Vandermoere Tomas Van De Sande Greet Tavernier Lore Lauwers Ellen Goovaerts Joris De Nies Stefaan De Neve 《植物养料与土壤学杂志》2020,183(3):345-354
Environmental concerns and rapidly decreasing phosphorus (P) resources caused a renewed interest in improving soil P tests for a more efficient P fertilization. This led to the development of better P fertilizer recommendation systems for major arable crops and grass. Nevertheless, these P fertilizer recommendation systems seem to fail for intensive vegetable crops, with often a very short growing season and limited rooting system. This leads to low P use efficiencies in the horticultural sector. In order to address this problem we set up a study to answer following questions: (1) which soil P test predicts the plant available P content for intensive vegetable crops the best and (2) can new insights, such as combining different soil P tests, improve P fertilizer recommendations for intensive vegetable crops? To this end, bulk samples of 41 soils with very different P status (based on ammonium lactate extractable P) were collected. The plant available P content of these soils was determined using six commonly used soil P tests (P‐CaCl2, P‐water, P‐Olsen, P‐acetate, P‐lactate, and P‐oxalate) and a P fertilizer pot experiment with endive (a very P sensitive vegetable crop) was conducted. Six pots of each soil were planted with endive. Three of these pots received no P fertilization (0P) and three pots received ammonium polyphosphate equivalent to 24 kg P ha?1 (24P). All other factors were kept constant. Relative crop yield of the 0P fertilized plants compared to the 24P fertilized plants was determined. Plotting these relative yields against the P status of the soil per soil P test allowed to fit a Mitscherlich curve through the data. Also the combination of two different soil P tests to predict the relative yield with a Mitscherlich equation was evaluated. The coefficients of variation of the soil P tests, the R2 values and the relative standard errors of the parameter estimates revealed that P‐acetate and P‐water predicted the relative yield of the 0P plants the best and that combining two different soil P tests gave no extra predictive power. This finding may form the basis for the development of a new P fertilizer recommendation system for intensive vegetable crops, leading to an improved P use efficiency in horticulture. In order to develop this new system more data relating soil P test values with RY of intensive vegetable crops should be collected. 相似文献
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Lieven De Boever Dries Vansteenkiste Joris Van Acker Marc Stevens 《Annals of Forest Science》2007,64(6):621-630
This study focused on physical and mechanical properties of fast-growing poplar clones in relation to potential end uses with high added value. A total of 14 trees from three different clones, all P. trichocarpa × deltoides (T×D) hybrids, were felled in a poplar plantation in Lille (Belgium): six ‘Beaupré’, four ‘Hazendans’ and four ‘Hoogvorst’. Growth rate was found to have no significant influence on the physical mechanical properties. Although the investigated clones are genetically closely related, important variations in physical and mechanical properties were observed. Specific features such as spatial distribution of tension wood and dimensional stability are the main quality factors. It was concluded that ‘Beaupré’ is suitable for a wide range of high value added applications, such as plywood or construction wood. ‘Hazendans’ and ‘Hoogvorst’ will need adapted technology in processing. Further research is needed to characterize clonally induced variation in properties and to assess adequate processing strategies for multiclonal poplar stands. 相似文献