Excitatory phenomena following the use of propofol in dogs

Over a two month period, 148 dogs presented for surgery had general anaesthesia induced and sometimes maintained with propofol. Excitatory phenomena were recorded on 12 occasions. Signs included muscle twitching, opisthotonus and limb hyperextension (nine cases), and panting with associated activity of the brachiocephalicus muscle and tongue retraction (three cases). The records for a similar two month period were examined for data and observations relating to thiopentone. During this period anaesthesia was induced with thiopentone in 71 dogs and no excitatory phenomena were recorded.     

Persistence of salmonella enteritidis in poultry units and poultry food

1. Studies on the survival of Salmonella enteritidis in poultry units and food were carried out over a two‐year period.

2. The organism persisted for at least one year in an empty trial house at the laboratory in which naturally‐infected broiler breeder birds had previously been housed. A similar survival period was seen in a building which had housed an infected layer breeder flock, although infection was not detected in a subsequent pullet flock.

3. Salmonella enteritidis was also frequently found surviving outside poultry houses in small pockets of litter and fan dust which had been left after cleansing and disinfection of the site. On some poultry units S. enteritidis was also found in wild bird droppings.

4. Salmonella contamination appeared to persist preferentially in association with dust particles swept from the floor and in food troughs and S. enteritidis survived at least 26 months in artificially contaminated poultry food.     

Oat cells in the pathology of ovine pneumonia-pleurisy

Light microscope observations on oat cells in the ovine pneumonia-pleurisy complex are presented. This study is based on the experimental production of the disease by viruses and Pasteurella haemolytica. Oat cells appeared only in necrotic lesions associated with large numbers of P. haemolytica in the pneumonic lung. It is suggested that oat cells originate from blood monocytes, which transform into the oat shape when developing in the necrotic, hypoxic environment created by P. haemolytica. They were not, however, observed to be phagocytic. Oat cells are characteristic of pneumonic pasteurellosis but are not pathognomonic because they can also be found in extrapulmonary locations and in other pathological conditions of the lungs.     

Skin blackening during the cooking of spent laying fowls

1. Blackening of the skin in factory processed cooked hens has been associated with elevated copper levels.

2. The degree of blackening was not directly related to copper content although the latter level was always higher than in control hens.

3. Simulated factory procedures, using scald water at 53 °C or 60 °C containing 50 mg Cu²⁺/1 and 50 mg C1₂/1, produced blackened skins of varying intensity on cooking.

4. It is suggested that the problem arose from a malfunction of the chlorination plant which produced excessive levels of chlorine and low pH, followed by erosion of copper from water pipes and subsequent interaction of copper and chlorine with the chicken skin.     

Peripartal Endocrinology in the Mare and Foetus

The endocrine profiles in the periparturient mares are dominated by increasing concentrations of progestagens and decreasing oestrogens. These hormones are produced by precursors from the foetus, metabolized by the placenta and act primarily on the maternal uterus. The circulating concentrations of hormones in maternal plasma, generally, represent a small proportion of those metabolized by the foetus and utero-placental tissues. There is clear evidence that the foetal hypothalamo-pituitary-adrenal (HPA) axis initiates the process of foetal maturation and the hormonal cascade which culminates in parturition at term. The endocrine changes associated with abnormal pregnancy and abortion in late pregnancy are less well understood, as are the hormonal treatments needed to avert these problems. Further work is needed to establish the biological role of the various hormones present in pregnant mares and, in particular, those hormones which control myometrial quiescence.     

Influences of population density,temperature and latitude on the growth of invasive topmouth gudgeon Pseudorasbora parva

Plasticity in life‐history traits provides advantages for introduced fish in overcoming demographic bottlenecks that would otherwise inhibit establishment. Here, the influence of population density, temperature and latitude was tested on the growth increments and growth rates of invasive populations of topmouth gudgeon Pseudorasbora parva, a small Asian cyprinid fish that is invasive across Europe. Aquaria experiments tested the roles of fish number and temperature on growth increments under a fixed food supply, pond experiments tested the role of density on growth increments, and a field study completed in England and Wales tested the influence of density and latitude on growth rates. In aquaria experiments, whilst growth increments were higher at 21 and 23 °C than at 19 and 25 °C, fish number had a greater influence on growth than temperature. Higher growth increments were produced at lower densities. In experimental ponds, growth increments were significantly higher in ponds with low densities of P. parva compared with those at elevated densities. In the field study comprising 10 wild populations across a latitudinal gradient of 4.0°N, a difference in mean air temperatures of approximately 3 °C, and estimated densities between 0.5 and 65.0 m^?2, population density was the only significant predictor of growth rates. Whilst populations at very low densities comprised of significantly faster growing individuals, there were no significant differences when densities were between 15 and 65 m^?2. Thus, invasive P. parva populations have considerable growth plasticity, especially at low densities, with this likely to be important in their ability to colonise new environments.