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Maryam Mirderikvandi Heshmatollah Khosravinia Bahman Parizadian Kavan 《Journal of animal physiology and animal nutrition》2020,104(1):166-177
Two hundred fifty two male Ross 308 broiler chicks were raised to examine the effects of Satureja khuzistanica essential oils (SkEO; 0, 200, 300, 400, 500 and 600 mg/bird/day) administrated via oral gavage and dietary supplementation of acetic acid (AA; 0 or 20 g/kg) in a 6 × 2 factorial fashion using a complete randomized block design with seven replicates of three birds each. In Day 34 of age, liver fat percentage decreased by increasing SkEO levels in a quadratic trend (p < .05). Oral gavag of 200 and 300 mg of SkEO decreased AST activity by 16.67% and 16.94%, respectively, compared with the control birds (p < .05). In Day 38 of age, liver percentage was greater by 0.37% in the birds received 400 mg SkEO than those given 500 mg (p < .05). Liver fat percentage decreased in the birds fed the acidified diet and received 300 and 500 mg SkEO as well as in the birds offered 200 and 400 mg of SkEO and fed non-acidified diet than those received acidified diet with no SkEO administration (p < .05). Prevalence of score zero for hepatocytic vacuolations and necrosis was 80.00% and 42.42% in the birds receiving 600 mg SkEO respectively. Median for relative frequency of scores for hepatocytic vacuolations and hepatocytic necrosis was lesser in the birds received SkEO by oral gavage compared with that of control birds (p < .05). In conclusion, administration of SkEO via oral gavage reduced liver fat in broiler chicken but no consistent dosage could be verified as the effective dosage for all ages concerned. The acidified diet per se showed no evident effect on liver fat at all ages considered. The SkEO × AA interaction exhibited promising but unreliable effects on liver colour score in market age (42 days). 相似文献
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Min Zhang Dan Zheng Zhimei Peng Yuting Zhu Rongrong Li Qiong Wu Yan Li Hongyi Li Weihua Xu Mao Zhang Qichun Hung Yanfa Sun 《The Journal of Poultry Science》2021,58(2):131
In this study, signaling pathways and key differentially expressed genes (DEGs) involved in lipid metabolism in muscle and fat tissues were investigated. Muscle and abdominal fat tissues were obtained from 35-day-old female broilers for RNA sequencing. DEGs between muscle and fat tissues were identified. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of DEGs were performed. A total of 6130 DEGs were identified to be significantly enriched in 365 GO terms, most of which were involved in biological processes, cellular components, and molecular functions in muscle and fat tissues. Three important lipid signaling pathways (pyruvate metabolism, the insulin signaling pathway, and the adipocytokine signaling pathway) were identified among the fat and muscle tissues of broilers. The key common DEGs in these pathways included phosphoenolpyruvate carboxykinase 2 (PCK2), acetyl-CoA carboxylase 1 alpha and beta (ACACA and ACACB), and the mitogen-activated protein kinase (AMPK) gene family. Hence, our findings revealed the pathways and key genes and gene families involved in the regulation of fat deposition in the muscle and fat tissues of broilers. 相似文献