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131.
Oliver Schmied Gernot Scharf Monika Hilbe Ulrike Michal Kamil Tomsa Frank Steffen 《Veterinary radiology & ultrasound》2008,49(4):343-349
The clinical, neuropathologic, and magnetic resonance (MR) imaging features in four cats with necrosis of the hippocampus and piriform lobe are described. All cats had acute generalized seizures and behavioral changes including aggression, salivation, polyphagia, and disorientation. Routine hematologic, serum chemistry, and cerebrospinal fluid analyses were normal. MR imaging abnormalities were restricted to the area of the hippocampus and piriform lobe. The lesions were T2-hyperintense, T1-hypointense, and were characterized by various degrees of contrast enhancement. Lesions were consistent with necrotizing encephalitis. Two cats were euthanized and underwent postmortem examination within a week after MR imaging due to the lack of response to antiepileptic drug therapy and progressive neuropathy. The remaining two cats lived for about four months and were then euthanized because of persistent behavioral and neurologic signs; only one of these cats underwent postmortem examination with histopathologic examination. Histopathological findings were typical of severe, diffuse, bilateral symmetric necrosis, and degeneration of neurons in the hippocampus and piriform lobe, but an etiologic agent was not apparent. This apparently unique feline syndrome, now reported in Switzerland and Italy, has no known cause at this time. 相似文献
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Dirofilaria repens—An etiological factor or an incidental finding in cytologic and histopathologic biopsies from dogs 下载免费PDF全文
Katarzyna Paździor‐Czapula Iwona Otrocka‐Domagała Patrycja Myrdek Mateusz Mikiewicz Michał Gesek 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2018,47(2):307-311
Dirofilaria repens is an endemic, zoonotic parasite of carnivores, causing subcutaneous dirofilariasis, which is mostly asymptomatic. The aim of this study was to describe 22 cases of canine subcutaneous dirofilariasis. The cytologic and histopathologic samples were collected from dogs, which presented with various clinical signs such as cutaneous/subcutaneous nodules, hydropericardium, ascites, and lymphadenomegaly. The cytologic or histopathologic examination revealed purulent, pyogranulomatous, granulomatous or eosinophilic dermatitis/panniculitis, and the presence of D repens microfilariae or adults. The microfilariae or adults were also found incidentally in neoplastic cutaneous or subcutaneous tumors and in a sialocele. For the first time, microfilariae were also detected and described in pericardial and abdominal effusions and in enlarged reactive lymph nodes. Although it is well known that D repens can cause dermatitis and panniculitis in dogs, no previous reports of D repens microfilariae in body cavity fluids were found. The role of this parasite in the accumulation of body cavity fluid or in reactive lymphadenomegaly requires further investigation. Due to its zoonotic potential, and apparently underestimated pathogenicity, each case of canine subcutaneous dirofilariasis should be treated. 相似文献
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罗非鱼类立克次氏体病的组织病理学观察 总被引:1,自引:0,他引:1
本文主要研究感染类立克次氏体(Rickettsia-like organism,RLO)的养殖罗非鱼(Oreochromis aureus♂×Oreochromis niloticus♀)肝、脾、肾、肠、鳃和心脏的组织病理变化。感染类立克次氏体的罗非鱼各器官广布粗糙不圆整的白色小结节,这些结节为肉芽肿坏死灶,分层不典型,与周围健康组织的界限不甚明显;严重病变的组织坏死区域较大,与周围明显增生的细胞形成清晰的巨大"肉瘤"状肿物。经吉姆萨-瑞氏染色后,在病变组织内,尤其是脾肾组织的巨噬细胞胞质内可见蓝紫色球状或颗粒样、成簇分布的类立克次氏体。这些发现可为罗非鱼类立克次氏体病的病理学诊断提供依据。 相似文献
137.
A 60-day feeding trial was conducted to study the immuno-protective effect of microbial levan on Labeo rohita juveniles challenged with Aeromonas hydrophila. Six purified diets were prepared with different levels of microbial levan: control (no levan), T1 (Basal + 0.25%), T2 (Basal + 0.50%), T3 (Basal + 0.75%), T4 (Basal + 1%) and T5 (Basal + 1.25%), fed to six groups of fish in triplicate. Among the treatment groups the haemoglobin content and total leucocyte count were increased with a dietary supplementation of levan at 1% or more. An increasing trend for total erythrocyte count was observed with increasing level of dietary levan. Lower levan-supplemented groups showed a higher albumin/globulin ratio. As the levan supplementation was increased, there was a gradual increase in serum lysozyme activity and respiratory burst activity [nitroblue tetrazolium (NBT) assay] reduction values. The highest lysozyme activity and NBT were observed in the T5 group although this was similar to the T4 group ( P > 0.05). No significant histo-architectural changes were associated with dietary levan levels. After challenge with A. hydrophila , moderately degenerated hepatocytes, oedema and leucocytic infiltration in parenchymatous tissues, and extensive haemorrhage and haemosiderosis in the kidney were observed in the control group. However, the T5 group supplemented with 1.25% levan showed infiltrating leucocytes in the liver while the kidney showed only moderate degeneration of renal tubules. The relative survival per cent of juveniles after challenge with A. hydrophila was the highest in the T5 group followed by T4. This suggests that microbial levan at 1.25% can be used as dietary immunostimulant for L. rohita juveniles. 相似文献
138.
为研究守宫木对小鼠体重增长和脏器显微结构的影响,将试验小鼠分为高、中、低3个试验组和1个对照组;隔5 d称重1次,第30天处死动物进行组织病理学检测。结果表明,高剂量组小鼠体增重显著慢于低剂量组和对照组(P<0.05),低剂量组显著快于对照组(P<0.05); 试验组小鼠肝脏和肺脏发生轻到中度病变。试验结果说明,守宫木对小鼠体重增长及组织器官显微结构均有一定的影响。 相似文献
139.
Identification and Pathogenicity of Pseudomonas aeruginosa DJ1990 on Tail and Fin Rot Disease in Spotted Snakehead 下载免费PDF全文
Dibya J. Saikia Pritam Chattopadhyay Goutam Banerjee Bandita Talukdar Dandadhar Sarma 《Journal of the World Aquaculture Society》2018,49(4):703-714
Tail and fin rot disease (TFRD) is a big issue in the production of spotted snakehead, Channa punctata Bloch. The aims of the present study were to isolate and identify the bacterial pathogen causing TFRD, to detect histopathological changes in tissues (fin, tail, liver, and kidney), and to ascertain the antibiotic sensitivity pattern of the isolate. Out of six bacterial isolates, only the isolate DJ1990 was found to be the causal candidate of TFRD in C. punctata. Identical histopathological changes were detected in tail, fin, liver, and kidney under light and scanning electron microscope in both collected diseased fish and artificially infected fish. The isolate was identified as Pseudomonas aeruginosa strain DJ1990 (National Center for Biotechnology Information Ace. No. KX709967) based on the biochemical characterization tests and 16S rDNA sequence‐based phylogeny analysis. Artificial challenge test demonstrated that the strain DJ1990 was highly virulent (100% mortality at 48 h of postinjection period at the concentration of 1.5 × 107 CFU/g of body weight) for C. punctata. The isolate exhibited sensitivity to the broad‐spectrum antibiotics but was resistant against aztreonum. To the best of our knowledge, this is the first report of P. aeruginosa as a TFRD‐causing candidate in C. punctata. 相似文献
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