丙烯海松双酰基硫脲衍生物的合成及抑菌活性研究

松香与丙烯酸通过Diels-Alder双烯加成反应得到丙烯海松酸,丙烯海松酸经酰氯化和硫脲化合成了6个未见报道的双酰基硫脲衍生物,通过IR、NMR、MS和元素分析等对产物进行了表征.初步的活性结果显示,丙烯海松双酰基硫脲衍生物对大肠杆菌和金黄色葡萄球菌都具有较好的抑制作用,特别是丙烯海松双-(3,5-二苯基)硫脲(4f...     

Bioactive saponins from the fruits of Aesculus pavia L

Continued chemical investigation on the fruits of Aesculus pavia L. resulted in theisolation and identification of two new oleanolic acid saponins, namely vaccaroside A (1) andvaccaroside B (2). The isolated furostanol saponins were evaluated for cytotoxic activity againsthuman normal amniotic and human lung carcinoma cell lines using neutral red and MTT assays.In vitro experiments showed significant cytotoxicity in a dose dependent manner with IC50 valuesin the range of 27.80–79.02 μM.     

A new coumestan with immunosuppressive activities from Flemingia philippinensis

A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 and 4 showed strong lymphocyte proliferation inhibitory activity with an IC₅₀ value of 1.04-2.76 μM, and the low cytotoxicity with the CC₅₀ value of 71.01 and 56.36 μM, respectively.     

New furostanol saponins from Smilax aspera L. and their in vitro cytotoxicity

The occurrence of the two new cis-fused A/B rings furostanol saponins (25S)-26-O-β-d-glucopyranosyl-5β-furostan-1β,3β,22α,26-tetraol-1-O-β-d-glucopyranoside and (25S)-26-O-β-d-glucopyranosyl-5β-furostan-1β,2β,3β,5β,22α,26-hexaol and the known compounds (25S)-26-O-β-d-glucopyranosyl-5β-furostan-3β,22α,26-triol-3-O-α-l-rhamnopyranosyl-(1→2)-O-β-d-glucopyranosyl-(1→2)-O-β-d-glucopyranoside and (25S)-26-O-β-d-glucopyranosyl-5β-furostan-3β,22α,26-triol-3-O-β-d-glucopyranosyl-(1→2)-O-β-d-glucopyranoside, trans-resveratrol, (+) catechin and (−) epicatechin in the rhizomes of Smilax aspera is reported. All saponins have been isolated as their 22-OMe derivatives, which were further subjected to extensive spectroscopic analysis. The isolated furostanol saponins were evaluated for cytotoxic activity against human normal amniotic and human lung carcinoma cell lines using neutral red and MTT assays. In vitro experiments showed significant cytotoxicity in a dose dependent manner with IC₅₀ values in the range of 32.98-94.53 µM.     

Two new benzofuran derivatives with anti-inflammatory activity from Liriope spicata var. prolifera

Two new benzofuran derivatives, 2-(4′-hydroxybenzyl)-5,6-methylenedioxy-benzofuran () and 2-(4′-hydroxybenzoyl)-5,6-methylenedioxy-benzofuran (), along with 8 known compounds were isolated from 60% EtOH extract of the fibrous roots of Liriope spicata var. prolifera. Their structures were elucidated on the basis of extensive spectroscopic analysis. In an in vitro bioactive assay, the two new benzofuran derivatives showed anti-inflammatory activity. Compounds 1 and 2 exhibited significant inhibitory activity against neutrophil respiratory burst stimulated by phorbol 12-myristate 13-acetate (PMA) with IC₅₀ value of 4.15 ± 0.07 and 5.96 ± 0.37 μM, respectively.     

Coast live oak, Quercus agrifolia, susceptibility and response to goldspotted oak borer, Agrilus auroguttatus, injury in southern California

Oak mortality is often associated with a complex of decline factors. We describe the morphological and physiological responses of coast live oak, Quercus agrifolia Née, in California to an invasive insect, the goldspotted oak borer (GSOB), Agrilus auroguttatus Schaeffer (Coleoptera: Buprestidae), and evaluate drought as a potential inciting factor. Morphological traits of 356 trees were assessed and physiological traits of 70 of these were monitored intensively over one growing season. Morphological characteristics of tree health included crown thinning and dieback; bole staining resulting from larval feeding; density of GSOB adult exit holes; and holes caused by woodpecker feeding. These characteristics were used to rank GSOB infestation/injury into four classes, and taken together, they explained 87% of the variation in a principal component analysis. Drought stress on various size/age and infestation classes of Q. agrifolia was measured by assessing branchlet pre-dawn and solar noon xylem water potential, leaf cell turgor potential, and water use efficiency over one growing season. Both morphological and physiological traits were highly variable in mature and old growth trees. Early summer plant water status (branchlet xylem water potential and water use efficiency) was similar between uninfested and newly colonized trees, suggesting that GSOB are not pre-selecting drought-stressed Q. agrifolia for oviposition. By late summer, leaf water and cell turgor potentials were lower in infested than in uninfested mature trees, suggesting that GSOB infestation causes drought stress in these trees. Among the tree size/age classes, infested old growth trees exhibited the greatest change in water use efficiency over the growing season, and showed greater morphological injury symptoms of decline than infested mature trees. Morphological attributes of decline in Q. agrifolia associated with GSOB were correlated weakly with increasing physiological drought stress among infestation classes of trees. We propose that the collection of morphological responses of Q. agrifolia to GSOB described here can be used to monitor the future expansion of the GSOB distribution as well as the GSOB-induced decline of Q. agrifolia in California.     

60种花卉多酚、黄酮含量及其抗氧化活性

为了筛选出抗氧化能力强的花卉品种,对60种花卉植物的50％乙醇提取物进行了多酚、黄酮含量测定,并对提取物进行清除DPPH的试验.结果表明:花卉中含有丰富的多酚和黄酮类物质,多酚含量在70 mg/g以上的花卉有芍药花、金盏菊、黄刺玫、美蔷薇、红玫瑰等,黄酮含量较高的花卉有连翘、马蹄莲、山楂、杏、榆叶梅等,含量在7.05～...     

施硅对玉米生长及蒸腾速率的影响

以玉米为试验材料,研究了土培条件下施Si与水分胁迫对玉米生长、蒸腾速率、叶片ABA浓度等的影响。结果表明:无论是否存在水分胁迫,施Si对玉米地上部生物量无显著影响;无论是否施Si,停止供水4d后玉米生物量明显降低;施Si显著降低了玉米植株的蒸腾速率,停止供水后其蒸腾速率明显低于正常水分供应处理,且随胁迫时间的延长,蒸腾速率逐渐降低;无论是否存在水分胁迫,施Si明显增加了玉米叶片的ABA浓度,同时水分胁迫增加了玉米叶片的内源ABA浓度。     

太行山山前平原冬小麦生长季硝态氮的淋失研究

试验研究太行山山前平原冬小麦生长季NO3- N淋失结果表明 ,该区现有灌溉施肥制度冬小麦生长季存在NO3- N的淋失 ,且主要发生在底墒水和返青水灌溉时期。整个冬小麦生长季施N水平为 1 0 0kg hm2 、2 0 0kg hm2 和 4 0 0kg hm2 时 ,通过 1 80cm土层界面的NO3- N淋失量分别为 0 1kg hm2 、2 2 1kg hm2 和 1 1 0 1kg hm2 。     

蒸发条件下粘土层对土壤水和溶质运移影响的模拟

以土壤水和溶质运移的动力学原理为基础 ,采用数值模拟方法 ,研究了在浅层地下水和蒸发条件下含有粘土层土壤的水和Cl-的运移状况 ,重点探讨了两种粘土的层位和层厚对水和Cl-运移影响的差别及原因。研究结果表明 ,粘土层对土壤的水和溶质运移影响的程度 ,与层状土壤中该粘土及其组合土壤的水力学性质有关。本文模拟的重粘土 (简称Y粘土 )与轻壤土所组成的层状土壤 ,其基本情况为 ,随粘土层层位的升高和层厚加大 ,土壤水分蒸发和地下水补给速率降低 ,Cl-积累减少。而轻粘土 (简称R粘土 )与轻壤土所组成的层状土壤 ,由于它们的导水率曲线在压力水头h约 - 10 0 0cm处相交 ,当h低于此值时 ,R粘土的导水率就大于轻壤土的。因此 ,蒸发、补给速率和Cl-积累强度出现以顶位最高 ,甚至高于均质轻壤土 ,其次为底位 ,最低为中部层位的现象。在蒸发条件下Cl-在剖面中的积聚部位主要是土表。粘土层的存在 ,起到了阻滞作用 ,而阻滞程度则与该粘土水力学性质、层位、厚度和地下水埋深有关