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11.
Fisheries Science - Cytokines are low molecular weight glycoproteins involved in the regulation of the immune system, and more than 100 cytokines have hitherto been identified in humans. Cytokines... 相似文献
12.
Akio Koizumi Jun-ichi Motoyama Kei Sawata Yoshihisa Sasaki Takuro Hirai 《Journal of Wood Science》2010,56(3):189-193
To estimate the wind force that causes windthrow damage to a tree, the drag coefficients of actual-sized trees were evaluated
by a field test method. In this method, wind velocity and stem deflection were monitored simultaneously. The wind force acting
on a tree crown was calculated from stem deflection; stem stiffness was evaluated by conducting tree-bending tests. The results
of tests conducted on three poplar trees showed that drag coefficient decreased with an increase in wind velocity. Although
the variation in the drag coefficient was large at low wind velocity because of the vibrating behavior of the stem subjected
to variable wind force, the variation at wind velocities above 10 m/s was small. The average drag coefficient at a wind velocity
of 30 m/s was estimated by the curve-fitting of a power function to the wind velocity-drag coefficient relationship to be
0.102, which was smaller than that of actual-sized conifers studied in previous wind tunnel experiments. The drag coefficients
of these crown areas in the defoliation season were smaller than those measured in the leafy season. 相似文献
13.
Takayuki MIURA Yasuhiro KISHIOKA Jun-ichi WAKAMATSU Akihito HATTORI Takanori NISHIMURA 《Animal Science Journal》2010,81(1):102-107
Myostatin, a member of the TGF-β superfamily, is a negative regulator of skeletal muscle mass. We have recently demonstrated that decorin binds to myostatin in vitro , and that immobilized decorin within the collagen matrix prevents myostatin-mediated inhibition of myoblast proliferation. However, little is known about other ECM molecules that bind to myostatin and modulate its activity. Thus, in the present study, we investigated the interaction of several other ECM molecules with myostatin. We here show that fibromodulin, fibronectin and laminin bind to myostatin in the presence of Zn2+ with a dissociation constant ( KD ) of 10−10 ∼10−8 mol/L. Fibromodulin shows the highest affinity for myostatin among them. These results suggest that these ECM molecules may modulate myostatin activity like decorin does. 相似文献
14.
15.
For the past ten years much work has been carried out on clay minerals of volcanic ash soils. Most investigators have reported that allophane is dominant among clay minerals of volcanic ash soils and crystallizes to halloysite or meta-halloysite with the advance of weathering (1–8). On the other hand, UCHIYAMA, MASUI and ONIKURA (1960) found that montmorillonite predominates in the clay fraction of volcanic ash soil in Kawatabi (9). Furthermore, MASUI, SHOJI and UCHIYAMA (1966) showed that the major crystalline clay minerals of volcanic ash soils in the Tohoku district are montmorillonite, vermiculite, intergradient montmorillonite-vermiculite and chlorite (10). They also showed that these minerals increase with the advance of weathering and that kaolin minerals are minor constituents. 相似文献
16.
Jun-ichi Ikeda 《Soil Science and Plant Nutrition》2013,59(4):703-710
To characterize the regulation site and manner of the abundant nodulation in the soybean (Glycine max (L.) Merr.) cv. Kitamusume, three grafting eperiments were carried out as follows: reciprocal wedge grafting and inter-cultivar approach grafting between Kitamusume and a normal nodulating cultivar, Toyosuzu, as well as wedge grafting of scions of the supernodulating mutant En6500 onto either Kitamusume or Toyosuzu rootstock. In the reciprocal wedge grafting, the number of nodules per shoot dry weight and average weight per nodule in the grafted plants were consistent with those exhibited by the genotype of their rootstocks. Approach grafting did not affect the number of nodules per shoot dry weight on either side of the inter-cultivar approachgrafted plant. Although grafting of the mutant scion resulted in the loss of the autoregulatory response from the roots of both cultivars, difference in the number of nodules per g shoot dry weight still remained between the two cultivars. These results suggested that the abundant nodulation in Kitamusume is controlled by the root in a non-systemic manner and is independent of the autoregulation mechanism. 相似文献
17.
Hitoshi Watanabe Shuji Tsuda Jun-ichi Fukami 《Pesticide biochemistry and physiology》1975,5(2):150-154
The effects of chlordimeform on rectus abdominis muscle of frog were investigated. Chlordimeform (10?3M) caused a slow contraction, and at lower concentration (10?5–10?3M) it inhibited the acetylcholine-induced contraction in noncompetitive manner. When chlordimeform was applied to the muscle of Rana catesbiana, K+-induced contraction was also inhibited in noncompetitive manner. Whereas it had no effect on caffeine-induced contraction.Chlordimeform-induced contraction was not affected by respective addition of d-tubocurarine (10?4M), procaine (10?3M), or eserine (0.3 mM), which results were same as that of K+-induced contraction. Chlordimeform, at lower concentration (10?5–10?3M), inhibits the acetylcholine- and K+-induced contractions probably owing to depression of not only the sensitivity of endplate but also the excitability of cell membrane. 相似文献
18.
Ching M. Wang Toshio Narahashi Jun-ichi Fukami 《Pesticide biochemistry and physiology》1975,5(2):119-125
The mechanism of action of chlordimeform on the frog sciatic nerve-sartorius muscle preparation has been studied by means of microelectrodes. Chlordimeform (0.1 mM) suppresses the amplitude of spontaneous miniature end-plate potentials without much changing their frequency. At 1 mM, it completely blocks the miniature end-plate potentials. The resting membrane potential is not affected. The end-plate potential evoked by nerve stimulation is also suppressed, while the action potential from the nerve terminal is not impaired. The sensitivity of the end-plate membrane to the transmitter substance as examined by iontophoretic applications of acetylcholine is effectively decreased by chlordimeform. The quantal content of transmitter release is not affected. It is concluded that the block of neuromuscular transmission by chlordimeform is due primarily to a depression of the end-plate sensitivity to the transmitter. 相似文献
19.
Suto J 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(4):303-309
Cq3 was identified in C57BL/6J (B6) x KK-Ay F2 mice as a quantitative trait locus (QTL) that controls plasma cholesterol and phospholipid levels, and normolipidemic B6 allele was associated with increased lipids. Cq3 was statistically significant in F2-a/a, but not in F2-Ay/a; probably because the Cq3 effect was obscured by introduction of the Ay allele, which in itself has a strong hyperlipidemic effect. Because the peak LOD score for Cq3 was identified near D3Mit102 (49.7 cM) on chromosome 3, linkage analyses with microsatellite markers located at 49.7 cM were performed in KK x RR F2, B6 x RR F2, and KK x CF1 F2. However, even a suggestive QTL was not identified in any of the three F2. By testing all pairs of marker loci, I found a significant interaction between Cq3 and the Apoa2 locus, and F2 mice with the Apoa2(KK)/Apoa2(KK); D3Mit102(B6)/D3Mit102(B6) genotype had significantly higher cholesterol levels than did F2 mice with other genotypes. The results showed that the ;round-robin' strategy was not always applicable to the search for QTL genes; probably because specific gene-to-gene interaction limited the validity of the strategy to the utmost extent. 相似文献
20.
Suto J 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(10):1121-1124
A brachypodism (brp) mutation arose spontaneously in the inbred NC mouse strain, producing a phenotype similar to that caused by bp mutation; therefore, it is strongly suggested that brp and bp are allelic. A series of bp mutations are due to defects in the growth differentiation factor 5 (Gdf5) gene. Nucleotide sequence analysis on the Gdf5 gene in NC-brp/brp mice revealed that an irregular insertion of a unit ;GGCAGCC' in exon 2 caused a frame shift leading to a premature stop codon. In addition to the known physiologic roles of brp, I found that brp significantly reduced the litter size. The brp is a novel mutant allele at the Gdf5 gene locus; I would like to name this allele Gdf5(brp). 相似文献