Plasma beta-endorphin and adrenocorticotrophin in young horses in training

A controlled period of submaximal exercise on a treadmill was used as a standardised stress test in 6 young horses to monitor the effects of training. Circulating plasma concentrations of immunoreactive beta-endorphin (IR beta-EP) were measured before, during and after the exercise period. The stress test was conducted on 3 occasions during an intensive training program lasting 14 weeks. In week 3 a marked increase in plasma IR beta-EP (P = 0.003) was demonstrated as a result of training, but by the last exercise test performed in week 9 no significant increase in plasma IR beta-EP concentrations could be detected. During the training period the basal concentrations of plasma IR beta-EP significantly decreased (P = 0.0059). Plasma adrenocorticotrophin (ACTH) did not increase during exercise, although there was a trend of decreasing basal plasma ACTH by the end of the training period. It was concluded that a standardised work test acted as a mild stress to unfit horses, but as the horses' fitness increased the hormonal response to exercise diminished. Basal plasma beta-EP concentrations were decreased with increasing fitness.     

Effects of antibiotic therapy at drying off on mastitis in the dry period and early lactation

Four strategies for selecting cows for intramammary therapy with benzathine cloxacillin at drying off were compared in 12 Victorian dairy herds. The bacteriological status of all quarters of all (1044) cows was determined just before drying off, within 2 d of calving, and again 3 to 5 months after calving. All cases of clinical mastitis (from calving to mid-lactation) were recorded. Cows not infected at drying off were allocated randomly to 2 subgroups of approximately 350 cows each: not infected, not treated (NI-NT), or not infected, all quarters treated (NI-AT). New infection rates in the dry period (3.8% for NI-NT vs 2.1% for NI-AT) and in early lactation (4.1% for NI-NT vs 3.9% for NI-AT) were low and these differences were not significant. Incidence of clinical mastitis in early lactation was almost 50% higher for the treated group of uninfected cows compared with the untreated group (0.05 less than p less than 0.1). Cows infected in one or more quarters at drying off were split randomly into 2 subgroups of approximately 170 cows each: infected, all quarters treated (I-AT), or infected quarters treated only (I-QT). The new infection rate during the dry period was nearly 4 times higher for I-QT (15.3%) due to significantly more new infections by Staphylococcus aureus and Streptococcus uberis.(ABSTRACT TRUNCATED AT 250 WORDS)     

Neurological diseases of ruminant livestock in Australia. III: bacterial and protozoal infections

Bacteria (including chlamydia) and protozoa can produce neurological disease in Australian ruminant livestock and the nature of the inflammatory and neuroparenchymal response is often suggestive of a particular aetiological agent. An overview of the clinicopathological features of infectious disease affecting the central nervous system (CNS) is followed by a discussion of important bacterial and protozoal infections in Australia. Each infectious disease is discussed in terms of classification and pathogenesis linked to clinical signs and gross and microscopic findings. The literature review is restricted to infectious conditions causing CNS disease in Australia. Sources include the Australian Veterinary Journal (over 50 years of articles), the quarterly newsletter of the National Animal Health Surveillance System and the Animal Health Surveillance Quarterly.     

Congenital biliary atresia and jaundice in lambs and calves

An outbreak of congenital biliary atresia and jaundice is described, in which approximately 300 crossbred lambs and 9 crossbred calves died. The affected animals failed to thrive, developed jaundice and white scours and died within 4 weeks of birth. A common feature of this outbreak and a similar occurrence 24 years previously was the grazing of plants growing on the exposed silt foreshores of Burrinjuck Dam by ewes and cows in the early stages of pregnancy. Epidemiological and pathological findings suggested that a toxic insult to the foetus in early gestation caused choledysgenesis and biliary atresia, leading to diffuse, subacute to chronic cholangiohepatopathy and cirrhosis.     

Strategies for mastitis control: dry cow therapy and culling

SUMMARY The effects of three selection strategies for dry cow therapy on prevention of new infections and rate of antibiotic usage were compared. Quarter infection status of 1044 cows in 12 herds was determined by bacteriological methods at drying off, calving and three to five months into the following lactation. Cows that were uninfected at drying off were randomly allocated to treatment (whole udder, dry cow therapy) and non-treatment groups. Infected cows were randomly allocated to whole udder or infected quarter only treatments. The strategies compared were blanket treatment (treat all quarters of all cows), selective cow treatment (treat all quarters of any cow infected in one or more quarters) and selective quarter treatment (treat infected quarters only). Selective cow treatment was identified as the preferred strategy. Blanket treatment resulted in increased antibiotic usage (15.5 vs 6.4 tubes per infection eliminated) with no additional benefit, and selective quarter treatment resulted in a higher new infection rate (6.4%vs 3.9% quarters) in the dry period. The prevalence of infection within a herd at drying off had no influence on new infection rates in the dry period or early lactation. The cure rate after dry cow treatment (mean of 66%) decreased significantly with increasing age (P < 0.001). Cows infected in the previous lactation contributed over 76% of infections at calving and nearly 70% at mid-lactation. To lower the incidence of mastitis in a herd, a greater emphasis on culling of older infected cows and prevention of new infections during lactation is needed.     

Time Empty and Ketone Body Status in the Early Postpartum Period of Dairy Cows

This study aimed to assess the effect of ketone body status early postpartum on time empty in 74 multiparous dairy cows under field conditions. Animals were equally distributed across eight farms and were controlled by the same herd‐fertility‐monitoring programme. Cows were visited twice antepartum and six times postpartum at weekly intervals between 0530 and 0830 a.m. On these occasions, body condition scores and milk yields were measured, blood and milk samples were taken, cows were gynaecologically examined, and parameters of reproduction were recorded. Cows with a time empty of less or more than 80 days were classified as early and late conceiving cows (EC and LC, respectively). A time empty of 80 days results in calving‐to‐calving intervals of 1 year and classification based on this threshold value resulted in groups of equal size and equal distribution of EC and LC within farms. Ketone bodies measured were β‐hydroxybutyrate in blood and acetoacetate and acetone in blood and milk. Blood and milk ketone body concentrations, as well as the ratios of acetoacetate and acetone to β‐hydroxybutyrate, over the first 6 weeks postpartum were higher in LC than in EC, whereas plasma glucose and non‐esterified fatty acids and milk fat, protein and urea concentrations did not exhibit clear differences between groups. Ketone body concentrations were as good predictors of time empty as ketone body ratios and might have practical impact in herd‐fertility‐monitoring programmes.     

Soil water dynamics,herbage production and water use efficiency of three tropical grasses: Implications for use in a variable summer‐dominant rainfall environment,Australia

In the moist mid‐latitudes of eastern Australia, soil water dynamics, herbage production and water use efficiency (WUE) were monitored during 2006–2008, for five perennial pastures: digit grass (Digitaria eriantha), Rhodes grass (Chloris gayana), forest bluegrass (Bothriochloa bladhii), native grass (Bothriochloa macra and Rytidosperma bipartita dominant), lucerne (Medicago sativa); and two forage crops: oat (Avena fatua) and sorghum (Sorghum bicolor). Ground cover formed more quickly in Rhodes grass and lucerne (>70% ground cover in 120 and 175 days after sowing [DAS] respectively) than in forest bluegrass and digit grass (245 and 365 DAS respectively). Values of maximum extractable water (MEW) for Rhodes grass and lucerne were similar (180–242 mm), while values for digit grass and forest bluegrass (129–175 mm) were equal to or greater than those for native grass, and two annual forage crops (77–144 mm). Lucerne expressed the maximum root depth (1.46 m), while values for the tropical grasses (0.96–1.39 m) were greater than native grasses and forage crops (0.87–0.96 m). Native grasses (6.5–12 t DM/ha) had the lowest herbage production, which resulted in values of WUE that were significantly less than most other treatments (16–21 vs. 23–43 kg DM ha^?1 mm^?1). Digit grass (33–34 kg DM ha^?1 mm^?1) had higher WUE compared with the other tropical grasses (20–27 kg DM ha^?1 mm^?1). The data collected here suggest that a forage system comprising digit grass, lucerne and forage oat would provide high production and WUE in this environment.