食管癌切除术后并发胸胃排空障碍的诊断与防治

从１９７３年１月至１９９５年２月治疗食管癌切除术后胸胃排空障碍１１例。１０例行１１次手术：膈下胸胃十二指肠吻合术１例，胸内胸胃空肠合术２例，幽门区纵行全层切开横行缝合术１例；粘连松解术７例，其中同时行十二指肠松解术１例，幽门成形术２例。术后均解除梗阻。还就此症的诊断和预防作了讨论。     

Experimental Pathological Study of Acute African Swine Fever

To study the clinicopathology and histopathology of African swine fever (ASF), and to explore the internal relationship between pathological changes and disease occurrence and development and its pathological mechanism, 13 Landrace pigs with bodyweight about 20 kg were intramuscular injected with African swine fever virus (ASFV), strain Pig/HLJ/18 at a dose of 10²HAD₅₀·mL^-1. During the experiment, all the dead pigs were systematically dissected and sampled, paraffin sections were produced, and haematoxylin-eosin staining was performed. Clinicopathological evaluation standards for acute ASF were established, then pathological lesions (classification variables) were expressed by counting frequency and percentage, and the lesion degree (continuous variables) was graded and scored according to different pathological changes of various tissues and organs. The results showed that all infected pigs were in line with the clinical characteristics of ASF, including acute, febrile and highly infectious, with a 100% incidence rate and 100% mortality. The dead pigs showed typical characteristics of septicemia, cadavers prone to corruption, blood clotting adverse or hemolysis, rigor mortis incomplete. The main pathological lesions were hemorrhagic necrotizing lymphadenitis, acute inflammatory splenomegaly (septic spleen), cerebral edema, pulmonary edema and lung consolidation et al. The spleen and lymphonodus are the target organs attacked by ASFV, with the most significant lesions, the earliest occurrence time, the longest duration and the highest frequency. The most prominent pathological changes are blood circulation disorders, including multiple pathological manifestations such as edema, hyperemia, congestion, hemorrhage, infarction, disseminated intravascular coagulation (DIC), and the most important characteristics are hemorrhagic lesions. The inflammatory reaction of lymphocytic exudation caused by ASFV runs through the whole process, especially in the middle and later stages of the course. The results suggest that the main pathological process of acute African swine fever is a typical immune/inflammatory cascade reaction and severe systemic blood circulation disorder, which resulted in the high incidence rate and high mortality rate of acute ASF.     

Endocrine differentiation and its mechanism in endometrial carcinoma

AIM:To investigate endocrine differentiation and its mechanism in endometrial carcinoma.METHODS:Endocrine cells (EC) were identified by immunohistochemical staining of chromogranin A in 50 cases of endometrioid adenocarcinoma and 20 cases of normal endometrium. Double-label techniques were used for simultaneous demonstration of the CgA and cytokeratin.RESULTS:The positive rate of CgA in endometrioid adenocarcinoma was 44.0%, and was significant higher than that in normal endometrium (15.0%, P＜0.05). Scanty EC was present in normal endometrium. The number and staining intensity of EC in endometrioid adenocarcinoma were greater than that in normal. Co-expression of CgA and cytokeratin were detected in endometrioid adenocarcinoma.CONCLUSION:The presence of endocrine cells in endometrioid adenocarcinoma showed heterogeneity of tumors. The occurrence of "Multidirectional differentiation cells" within the endometrioid adenocarcinoma may indicate that endocrine cells derive from malignant cells of multidirectional differentiation.     

帆式张网网囊网目选择性能研究

分别对规格为４０、５０、６０、７０和８０ｍｍ网目的帆式张网网囊进行各４０网次的选择性试验,分析不同网囊规格的网目选择性能,探讨东海区帆式张网网囊的最小网目尺寸。结果表明,选择规格５５ｍｍ的网囊网目尺寸较为适宜。     

全株玉米青贮饲养肉牛最佳日粮组合模式研究

对肉牛常用饲料进行营养价值评定,并选择36头6～24月龄西杂肉牛分4组分别采食不同组合日粮,试验期63～68 d.结果表明,不同饲料之间蛋白含量、有效降解率和有效能含量存在较大的差异.肉牛代谢体重干物质采食量与日粮粗蛋白含量之间存在极显著正相关关系,日增重随代谢体重采食量的增加呈直线增加,经济效益随肉牛日增重的增加而增加.以青贮 秸秆 0.5 kg肉牛浓缩料、青贮 秸秆 2 kg肉牛精料补充料、青贮 牧草 0.5 kg肉牛浓缩料、青贮 牧草 2 kg肉牛精料补充料日粮组合分别饲养西杂肉牛,日增重(ADG)分别为0.66 kg、0.90 kg、0.92 kg、1.08 kg;体况评分(BCS)分别增加0.33分、0.42分、0.56分、0.69分;日盈利分别为3.44元、4.22元、4.70元、4.41元.说明,以全株玉米青贮 优质牧草粗饲料组合饲养肉牛,再补饲含高蛋白和能促进肉牛生长及提高纤维饲料消化率的瘤胃微生物所必须矿物质的肉牛浓缩料或肉牛精料补充料,可使肉牛达到较好的增重,并获得较高的收益.     

猪瘟病毒与猪附红细胞体混合感染的诊治

2005年7月,梧州市长州区倒水镇某村猪群暴发以高热、皮肤发红,腹下及四肢下部出现出血斑点为主要症状的疾病.根据临床症状、剖检变化及实验室检验等综合诊断,确诊为猪瘟与猪附红细胞体病混合感染,现报告如下:     

可发酵碳水化合物减少猪场臭气的机理和应用

可发酵碳水化合物,添加在猪日粮中到达后肠作为微生物发酵的底物,通过改变猪肠道和粪便中的微生物及其发酵过程,改变粪尿的理化特性,来减少氨的挥发以及臭气的产生.本文对臭气和除臭方法进行了简单的介绍,并综述了通过在猪日粮中添加可发酵碳水化合物来控制猪场臭气的机理和应用效果.     

亚热带地区冷季型草坪草夏季休眠控制研究

通过了解冷季型草坪草的特性,研究冷季型草坪草在夏季的生长状况和一些相关生理指标,找出冷季型草坪草夏季休眠的原因和耐热性机理,从而推广冷季型草坪草在园林绿地中的广泛应用,促进我国园林绿化事业的迅猛发展。     

家禽抑制素和活化素结构与功能的研究进展

许多研究显示,利用活化素和各种来源的抑制素作免疫原,可不同程度地提高家禽的排卵率和产蛋率.因此,研究家禽的这2种激素,对提高家禽产蛋量和繁殖性能具有重要的现实意义.文章对家禽抑制素和活化素的来源、结构特性及其对家禽生产性能的作用进行了综述.     

复方黄柏颗粒剂在小鼠体内的药代动力学

为探讨复方黄柏颗粒剂有效成分-盐酸小檗碱在小鼠体内的药动学特征,按25 g/kg(相当于盐酸小檗碱10.95 mg/kg)的剂量经口给予小鼠复方黄柏颗粒剂,用高效液相色谱法检测用药后不同时间血浆中盐酸小檗碱的质量浓度,研究在小白鼠体内的药物动力学。结果表明口服复方黄柏颗粒的有效成分-盐酸小檗碱在小鼠体内的药时数据符合开放性二室模型,动力学方程为C=17.8e-0.859 81t 14.51e-0.636 1t。主要药代动力学参数:t1/2α为(0.81±0.07)h,t1/2β为(5.25±2.96)h,t1/2Ka为(0.76±0.05)h,AUC0→∞为(3.389 3±0.437 4)mg.L-1.h,CL/F为(3.281 8±0.446 3)L/h,Vd/F为(13.65±22.38)L/kg,Tpeak为(1.617 19±0.056 50)h,Cmax为(1.149 98±0.056 04)μg/mL。