疑似牛结节性皮肤病防治的浅析与体会

牛结节性皮肤病(Lumpy skin disease,LSD)是由羊痘病毒属牛结节性皮肤病病毒(LSDV)引发的一种急性、热性传染病.2019年8月在我国新疆伊梨州首次发现,其临床特征表现为全身皮肤出现结节、肿块,所以又称为牛疙瘩皮肤病,我国暂列为二类动物疫病.     

耕牛结节病症状及综合防治对策

耕牛结节病又称牛结节性皮炎、牛结节疹、牛疙瘩皮肤病,由牛疙瘩皮肤病毒引起的一种急性、亚急性传染病,在夏秋季节多发,可通过病牛污染的环境、用具、粪便分泌物以及蚊虫等传播.该病被世界动物卫生组织列为通报的疾病,目前我国按二类动物疫病进行管理,并采取相应的防控措施.龙胜县2021年8月份首次发生该病,为两个相邻乡镇即平等镇广...     

牛结节性皮肤病的综合防控措施

牛结节性皮肤病是由牛结节性皮肤病病毒引起的一种牛病毒性传染病.临床上以病牛持续高热、皮肤出现大量疙瘩样结节为特征.该病于2019年8月首次传入我国新疆伊犁州,是世界动物卫生组织(OIE)要求通报的疫病.2022年2月10日,农业农村部发布公告,将牛结节性皮肤病由一类动物传染病调整为二类动物传染病.本文介绍了牛结节性皮肤...     

牛结节性皮肤病诊断及防控

牛结节性皮肤病是一种急性、亚急性传染性疾病。由于养殖户不科学地引种行为,造成该类疾病从其他国家引入本地区。牛结节性皮肤病又被称为牛结节疹、牛结节性皮炎或者牛疙瘩皮肤病,是由结节性皮肤病毒引发的一种急性亚急性传染性疾病。该类疾病被世界动物卫生组织规定为必须通报的疾病,我国将其划归为一类重大动物疫病。牛结节性皮肤病首先发生于新疆地区,随后由于不科学的运输和引种造成该类疾病,呈现逐渐扩大蔓延的趋势,带来的损失十分严重。需要掌握牛结节性皮肤病的具体流行特点、临床表现,做到及时发现及时处置,控制疫情的传播蔓延,确保我国牛养殖安全。该文主要论述牛结节性普皮肤病的诊断和防控。     

牛疙瘩皮肤病的流行与诊断

牛疙瘩皮肤病是由疙瘩皮肤病病毒引起的牛急性、亚急性或慢性传染病。其典型的临床特征是病牛发热、消瘦,淋巴结肿大,皮肤水肿,局部形成坚硬的结节或溃疡。感染牛消瘦,奶产量下降,皮张鞣制后有凹陷或孔洞而导致其利用价值大大降低。     

牛结节性皮肤病与常见牛皮肤病的鉴别诊断

牛结节性皮肤病(LSD)又称疙瘩皮肤病,是由痘病毒科山羊痘病毒属牛结节性皮肤病病毒引起的急性、亚急性或慢性引起的牛全身性感染疫病。及早鉴别诊断,防止疫情扩散,尤为重要。本文通过简要叙述牛结节性皮肤病和常见牛皮肤病的病原、流行病学、临床症状、鉴别诊断等,为快速准确诊断疾病提供参考。     

牛结节性皮肤病诊断与综合防控措施

牛结节性皮肤病又称牛结节疹、牛结节性皮炎或牛疙瘩病,是由牛结节性皮肤病病毒引起的牛传染性疾病,本病被世界动物卫生组织列为法定报告的动物疫病,同时也被列为我国进境动物检疫的一类疫病.农业农村部暂对其按二类动物疫病进行管理,要求各部门通过科学有效的技术手段和管理措施加以防控,确保养牛产业健康稳定发展.     

牛结节性皮肤病的诊断及防控措施

牛结节性皮肤病(Lumpyskindisease,LSD)又称牛结节疹、牛疙瘩皮肤病和牛结节性皮炎,是一种由痘病毒科山羊痘病毒属的牛结节性皮肤病病毒(Lumpyskindiseasevirus,LSDV)引起的疫病,以全身皮肤出现结节性病变为显著特征[1].该病被世界动物卫生组织(OIE)规定为必须通报的动物疫病,我国...     

几种引起牛流产病毒的概述

本文主要介绍了能够引起牛流产的几种病毒的病原性、流行情况、传播途径以及诊断方法。这些病毒包括常见的牛病毒性腹泻病毒、牛疱疹病毒-1型、牛疱疹病毒-4型、蓝舌病毒、流行性出血热病毒、裂谷热病毒、赤羽病病毒、Aino病毒、疙瘩皮肤病病毒等。此外还介绍了与牛疱疹病毒-I型有亲缘关系的牛疱疹病毒-5型和能引起牛流产零星发生的牛细小病毒。     

浅析安西牛结节病的诊断及预防措施

牛结节病是一种由疙瘩皮肤病病毒感染引起的急性、亚急性或慢性传染性皮肤病。安西牛作为我国特有的生产潜力较大的优良种牛,感染该病后可严重影响其生产性能。本文通过介绍牛结节病的临床症状、病理变化、诊断方法及预防措施,以期为防控安西牛结节病提供参考。     

牛结节性皮肤病疫苗研究进展

牛结节性皮肤病可对病畜皮肤造成永久性损害，并会导致产奶量下降、生长发育迟缓、公畜不育和孕畜流产等严重后果，对经济生产具有重要影响。目前尚无治疗该病的特效药，使用安全有效的疫苗是防控该病传播的重要手段。牛结节性皮肤病弱毒活疫苗在许多国家已被成功用于该病的防控，除此之外，由于牛结节性皮肤病病毒与山羊痘病毒及绵羊痘病毒在基因组序列上的高度相似性，山羊痘病毒弱毒活疫苗和绵羊痘病毒弱毒活疫苗在许多地区也被用于该病的防控。牛结节性皮肤病病毒编码基因较多，目前尚未发现基因缺失疫苗和亚单位疫苗具有好的保护效果。近年来灭活疫苗在实验室研究中取得了较大进展，但仍需进一步大规模临床试验以证明其有效性。此外，牛结节性皮肤病病毒作为一种痘病毒，已被证明是表达多种病原微生物抗原的有效载体之一。笔者主要总结了当前牛结节性皮肤病疫苗的研究进展，对弱毒疫苗、灭活疫苗、基因缺失疫苗和亚单位疫苗的使用情况、保护效果及研究方向等方面进行了综述，以期为牛结节性皮肤病疫苗的研发和疫病的防控提供新的思路和见解。     

牛结节性皮肤病疫苗的研究进展

牛结节性皮肤病是由牛结节性皮肤病病毒引起的一种急性、亚急性或慢性传染病。患病牛的临床症状主要为发热、消瘦、淋巴结肿大、皮肤水肿、局部形成结节或溃疡,影响肉牛增重、奶牛产奶量等,对牛养殖业可造成严重经济损失。疫苗防控动物疫病是一种高效、可控措施,对疫病的预防发挥重要作用。近年国内外研究人员对牛结节性皮肤病疫苗进行研究,取得一定成绩。本文对牛结节性皮肤病疫苗研究进行综述,为后续牛结节性皮肤病疫苗研发提供参考。     

郏县红牛疥螨病的治疗办法

牛疥螨病是牛养殖业中的常见疾病,主要疥螨寄生引起,是一种皮肤性疾病。发病之后皮肤溃烂、结痂、化脓,有奇痒的症状,会导致皮肤的增厚。随着牛养殖业的规模化发展,该病发生的概率逐年提升,长期患病会影响红牛的正常休息和采食,造成红牛体重的下降,影响郏县雪花牛肉的品质。     

Eosinophilic papulocrustous dermatitis (miliary dermatitis) and eosinophilic inflammatory bowel disease in two cats

Two cats with chronic eosinophilic skin disease were investigated. The clinical investigation of the skin disease in one cat was limited and inflammatory bowel disease was diagnosed post mortem. A history of weight loss and a palpably thickened bowel in the second cat suggested concurrent gastrointestinal disease. Diagnosis of inflammatory bowel disease was confirmed on biopsy. Treatment with azathioprine and methylprednisolone acetate resolved the signs of gastrointestinal disease, the pruritus and 95% of the skin lesions. The concurrence of eosinophilic papulocrustous dermatitis and eosinophilic bowel disease raises the possibility of their being linked bv a common aetiology or pathophysiology.     

牛结节性皮肤病的流行与防控

牛结节性皮肤病(LSD)是由牛结节性皮肤病病毒(LSDV)引起的一种牛急性、亚急性病毒性传染病,临床主要表现为发热,皮肤出现结节,母牛流产、产奶量下降,公牛不育。文章对牛结节性皮肤病的病原学、流行病学、临床症状及病理变化、诊断、防控措施等方面进行了较全而的阐述,以期为该病的诊断和防控工作提供参考。     

Experimental induction of the cutaneous form of Marek's disease in broilers

Straight-run chickens of the Ross broiler hybrid were experimentally infected with the skin homogenates of sound broilers, broilers conditionally edible, and broilers confiscated for alternations in skin. The chickens infected with the homogenates of healthy skin were negative in the Marek's disease test. In 17% of the chickens infected with the skin from the conditionally edible broilers, macroscopically observable cutaneous lesions were induced and 60% of the infected chickens had microscopic changes in the skin; visceral organs were always affected by the infection. In the chickens infected with the skin of a confiscated bird, the long storage exerted its unfavourable effect and the infected birds were negative in the Marek's disease test. Our results indicate that the active form of Marek's disease was induced.     

Regional distribution of ten common skin diseases in dogs

We investigated the regional distributions of the most commonly diagnosed skin diseases in dogs from 17 North American veterinary teaching hospitals. Between January 1983 and December 1983, 11,456 diagnoses of skin disease were made. The 10 most common diagnoses were fleabite allergic dermatitis, skin cancer, pyoderma, seborrhea, allergy, demodectic acariasis (demodicosis), sarcoptic acariasis, immune-mediated skin disease, endocrine related skin disease, and acral lick dermatitis. Regional differences in the frequency of skin diseases were apparent. The northeast region had high frequencies of fleabite allergic dermatitis, allergy, and immune-mediated disease, and a low frequency of seborrhea. The midwest had a high frequency of seborrhea, and low frequencies of demodectic acariasis and allergy. In the plains region, low frequencies of fleabite allergic dermatitis, pyoderma, seborrhea, allergy, and demodectic acariasis were detected. In the west, the frequencies of fleabite allergic dermatitis, skin cancer, pyoderma, seborrhea, and acral lick dermatitis were high, whereas few dogs had allergic disease and sarcoptic acariasis. The southwest had high frequencies of fleabite allergic dermatitis and demodectic and sarcoptic acariasis. Fleabite allergic dermatitis, pyoderma, and demodectic and sarcoptic acariasis were frequently diagnosed in the southeast, but the number of dogs with seborrhea was low.     

Avidin-biotin-peroxidase complex immunohistochemistry to detect immunoglobulin in formalin fixed skin biopsies in canine autoimmune skin disease.

Avidin-biotin-peroxidase complex immunohistochemistry was used on formalin fixed, paraffin embedded, trypsin digested, skin biopsies to detect immunoglobulin deposition in dogs with autoimmune skin disease. Immunostaining by the avidin-biotin-peroxidase complex technique revealed intercellular and/or basement membrane immunoglobulin deposits in 27 of 28 dogs considered to have autoimmune skin disease by clinical and histological evaluation and in six of 19 dogs considered to have autoimmune skin disease by clinical evaluation but without histological confirmation. Similar immunostaining was not evident in five biopsies of normal skin or in biopsies from four dogs with noninflammatory dermatoses, but was present in biopsies from one of ten dogs considered by clinical and histological criteria to have an inflammatory dermatosis other than autoimmune skin disease. Detection of immunoglobulin deposits in skin biopsies by avidin-biotin-peroxidase complex immunohistochemistry offers numerous advantages over conventional immunofluorescence methods including the opportunity to precisely compare histological and immunological findings.     

牛结节性皮肤病病毒实验室检测方法研究进展

牛结节性皮肤病(LSD)是由牛结节性皮肤病病毒(LSDV)引起的以发热、消瘦、皮肤水肿、局部形成坚硬的结节或溃疡、淋巴结肿大等为主要特征的急性、亚急性传染病。本病目前尚无特效治疗药物,疫苗接种是当前主要的防控措施,但我国目前并没有针对该病的疫苗,因此建立快速准确的检测方法显得尤为重要。本文从该病的病毒分离和鉴定、血清学及分子生物学等方面对LSDV的最新实验室检测方法研究进展进行了综述,以期为LSD的诊断和防控提供参考。