规模猪场猪伪狂犬病的净化研究

猪伪狂犬病是由伪狂犬病病毒引起的多种动物共患传染病,可引起仔猪大量发病死亡,母猪流产、死胎等繁殖障碍,育肥猪生长发育缓慢,经济损失惨重。为净化规模猪场的猪伪狂犬病,试验采用综合性的净化措施,除淘汰病猪及临床症状猪、加强饲养管理等技术措施外,采用猪伪狂犬病弱毒疫苗加强免疫,结合野毒抗体监测,成功的根除了伪狂犬的感染。     

猪伪狂犬病的流行、诊断与防制

猪伪狂犬病是由伪狂犬病病毒引起的急性传染病,感染猪的临床特征为体温升高,新生仔猪出现神经症状,还可侵害消化系统。成年猪常为隐性感染,妊娠母猪感染后可引起流产、死胎及呼吸系统症状,无奇痒。公猪表现为繁殖障碍和呼吸系统的临诊症状。本病也可发生于其他家畜和野生动物。     

猪伪狂犬病的流行、诊断与防制

猪伪狂犬病（PPR）是由伪狂犬病病毒引起的急性传染病,感染猪的临床特征为体温升高,新生仔猪表现神经症状,还可侵害消化系统。成年猪常为隐性感染,妊娠母猪感染后可引起流产、死胎及呼吸系统症状,无奇痒。公猪表现为繁殖障碍和呼吸系统的临诊症状。本病也可发生于其他家畜和野生动物。     

云南怒江地区猪伪狂犬病的血清学调查

伪狂犬病又名狂痒病,是由伪狂犬病病毒引起的猪和其他动物共患的一种急性传染病。其特征为发热、脑脊髓炎症状,但成年猪常为隐性感染,可有流产、死胎和呼吸道症状,新生仔猪除有神经症状外还可侵害消化系统。为了解该病在怒江州的感染情况,我们于2004—2005年在全州进行了猪伪狂     

猪伪狂犬病诊断技术研究进展

猪伪狂犬病是由疱疹病毒科中的猪疱疹病毒Ⅰ型(Pesudorabies,virus,PRV)引起的一种以发热、奇痒及脑脊髓炎为主要临床症状的急性传染病[1].成年猪常为隐性感染,可见流产、死胎及呼吸困难症状,新生仔猪主要表现神经症状,也可侵害消化系.……     

猪伪狂犬病的研究进展

猪伪狂犬病（Pseudorabies,PR）是由猪伪狂犬病毒引起猪的一种急性传染病,可致妊娠母猪流产,产死胎及胎儿干尸化;对初生仔猪则引起神经症状,出现运动失调,麻痹,衰竭死亡,病死率100％;成年猪多呈隐性感染,但可引起呼吸道症状。猪伪狂犬病是猪群主要传染病之一,严重危害养猪业的健康发展,并造成巨大的经济损失。本文对该病的病原学、流行病学、临床症状、病理变化、诊断和防控方面的研究进展做一综述。     

猪伪狂犬病的致病机制与防控措施

猪伪狂犬病是由疱疹病毒科的伪狂犬病病毒(Pseudorabies Virus,PRV)引起的一种急性传染病。猪是该病毒的传染源及长期贮存宿主,该病毒可引起母猪繁殖障碍及仔猪的神经症状、严重的呼吸道症状,仔猪死亡率较高;耐过猪则生长减缓甚至成僵猪。近年来,PRV与其他病毒混合感染发生较多,是导致很多疾病综合征的病原之一。文章主要针对猪伪狂犬病的病原、流行病学、致病机制和防控措施进行综述,以期对猪伪狂犬病的防治提供参考。     

猪伪狂犬病的诊断及防制措施

猪伪狂犬病是由伪狂犬病病毒引起的一种急性传染病。感染猪的临床特征为体温升高，呼吸系统症状；仔猪神经症状；妊娠母猪感染后可引起流产、死胎；无奇痒。本病具有长期带毒、散毒的特点而且这种潜伏感染随时都有可能被其他应激因素激发而引起疾病暴发。     

育肥猪群猪伪狂犬病的防控

猪伪狂犬病病毒可感染各阶段的猪群并引起症状表现,是引起猪群育肥阶段呼吸道症状综合征的病原之一,严重影响猪群的生长速度和饲料报酬,但一般不直接引起死亡;临床上常因其他细菌性病原继发感染而加剧症状表现,出现高死亡率和病残淘汰。防控育肥猪群的猪伪狂犬病,应在做好常规基础免疫保健程序的基础上,重点控制细菌性病原的继发感染,如使用抗生素及自家细菌苗等。     

猪伪狂犬病病毒NP株的分离鉴定

2013年下半年,福建某免疫接种过猪伪狂犬病疫苗(Bartha)的规模化猪场大批妊娠母猪发生流产、新生仔猪发生共济失调的神经症状,疑似为猪伪狂犬病病毒感染发病症状,为确定发病原因,从该猪场疑似伪狂犬病病毒感染的仔猪脑、肝脏和肺脏中分离到一株未知病毒,PCR检测及测序比对鉴定为猪伪狂犬病病毒,并将分离的病毒命名为NP株。用Reed-Muench法测定分离株病毒的组织细胞半数感染量(TCID50)为10-9.13/0.1mL,动物攻毒试验出现猪伪狂犬病病毒感染的典型症状。试验结果表明,成功分离到一株猪伪狂犬病病毒毒株,为研究福建省猪群伪狂犬病病毒分子流行病学奠定基础。     

Heartworm in dogs in Canada in 1984

In late December 1984, 1853 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1984 and 35% of them responded. Veterinarians reported that 97,794 dogs were blood-tested to check for microfilariae and 1417 dogs (1.45% of those tested) were found with heartworm. Another 34 dogs were amicrofilaremic, but were diagnosed as having heartworm disease, to give the total number diagnosed in 1984 as 1451 (1.48%). Heartworm was reported from all provinces except Prince Edward Island and Newfoundland but most (1310) of the cases were in Ontario. In Quebec, 126 cases were reported mostly from west of Montreal.

Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 27% of the cases were observed with clinical signs of heartworm disease and 72% had a history of not having left Canada. Southwestern Ontario continued to be the primary focus of the infection.

     

Heartworm in dogs in Canada in 1985

In late December 1985, 1485 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1985 and 44% of them responded. Veterinarians reported that 137,300 dogs were blood-tested to check for microfilariae and 1210 dogs were found with heartworm. Another 36 dogs were amicrofilaremic but diagnosed with heartworm disease to give the total number diagnosed in 1985 as 1247 (0.91%).

Heartworm was reported from all provinces except Prince Edward Island, Newfoundland and Saskatchewan but most (1126) of the cases were in Ontario. Southwestern Ontario continued to be the primary focus of the infection in Canada. From Quebec, 91 cases were reported mostly from and around Montreal. From Manitoba, 19 cases were reported from Winnipeg and surrounding areas. Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 28% of the cases were observed with clinical signs of heartworm disease and 78% had a history of not having left Canada.

     

Heartworm in dogs in Canada in 1988

In late November 1988, 1581 small and mixed animal clinics and institutional veterinarians across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1988, and 46% of them responded. Veterinarians reported that 181,577 dogs were blood-tested for heartworm disease and 367 dogs were found with D. immitis microfilariae. Another 60 dogs were amicrofilaremic but diagnosed with heartworm disease to give the total number of cases diagnosed in 1988 as 441 (0.24%).     

Heartworm in dogs in Canada in 1989

In late November 1989, 1732 clinics and institutional veterinarians were sent a questionnaire to assess the status of Dirofilaria immitis, and 51.7% responded. Of 247,716 dogs tested, 394 had D. immitis microfilariae and 51 were amicrofilaremic for a total of 445 cases and heartworm prevalence of 0.17%. Most (408) of these dogs had no preventive medication and the prevalence among dogs tested and unprotected was 1.01%. That prevalence was considerably higher in endemic areas. Thirty-seven dogs with heartworm had preventive medication. Heartworm was most frequent in companion dogs over three years of age maintained outdoors in rural areas. About 75% of the cases had never left Canada, 26% had clinical signs and 125 were not treated.

Heartworm was reported from British Columbia, Manitoba, Ontario, Quebec, Nova Scotia and Newfoundland, but 383 cases were in Ontario. South-western Ontario was the primary focus of infection. There were 33 cases in Quebec and 24 in Manitoba, mainly found in and around Metropolitan Montreal and Winnipeg respectively.

     

Heartworm in dogs in Canada in 1987

In late November 1987, 1246 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1987, and 50% of them responded. Veterinarians reported that 165,428 dogs were blood tested for heartworm disease and 511 dogs were found with D. immitis microfilariae. Another 78 dogs were amicrofilaremic but diagnosed with heartworm disease to give the total number of cases diagnosed in 1987 as 589 (0.35%).     

Heartworm in dogs in Canada in 1986

In late December 1986, 1224 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1986; 46% of them responded. Veterinarians reported that 150,989 dogs were blood-tested for microfilariae and 869 dogs were found with heartworm. Another 65 dogs were amicrofilaremic but diagnosed with heartworm disease and one was found with heartworm at necropsy to give the total number diagnosed in 1986 as 935 (0.62%).

Heartworm was reported from Manitoba, New Brunswick, Ontario and Quebec, but most (810) of the cases were from Ontario. South-western Ontario continued to be the primary focus of the infection in Canada. There were 103 cases reported from Quebec, mostly from and around Montreal, and 21 cases from Manitoba, from Winnipeg and surrounding areas. Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 33% of the cases were observed with clinical signs of heartworm disease and 81% had a history of not having left Canada.

     

Heartworm in dogs in Canada in 1991

In late November 1991, 1883 clinics in Canada were sent a questionnaire to assess the status of Dirofilaria immitis in dogs in 1991 and there was a 60.0% response. There were 344,031 dogs tested for heart-worm (HW), 627 were found infected and the prevalence of HW infection was 0.18%. There were 417 dogs with HW in Ontario, 116 in Manitoba, 38 in Quebec, 53 in British Columbia, three in Alberta, and one in Nova Scotia. In British Columbia, all of the infected dogs but one were from the Okanagan valley which, as from 1991, is a new focus of infection in Canada. Most dogs with HW had not been on preventive medication in 1990, and the prevalence among dogs tested and unprotected was 0.59%. That prevalence was considerably higher in endemic areas. Companion dogs, over three years of age and maintained primarily outdoors in rural areas, were most frequently infected. One cat was diagnosed with D. immitis and 33 dogs had Dipetalonema reconditium.     

Heartworm in dogs in Canada in 1983

In late December 1983, 2 800 veterinarians across Canada were sent a questionnaire in order to assess the status of heartworm disease in Canada in 1983 and 26% of them responded. Veterinarians reported that 59 504 dogs were blood-tested to check for microfilariae and 771 dogs (1.30% of those tested) were found with Dirofilaria immitis. Heartworm disease was diagnosed in all provinces except New Brunswick and Newfoundland but most (733) of the cases were in Ontario.

Heartworm disease was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 31% of the cases were observed with clinical signs of heartworm disease and 64% had a history of not having left Canada. Southwestern Ontario continues to be the focus of the infection and most of the dogs there had not left the province previously.