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宠物临床对犬血液肿瘤疾病的诊断主要基于病理组织学技术,目前在及时确诊方面仍有待完善。为探索系统、可靠和快速的犬血液肿瘤诊断方法,本试验拟对临床21例犬血液肿瘤疑似病例,通过血常规检查、血涂片分类计数、影像学检查、骨髓穿刺和骨髓液涂片技术综合应用以确诊肿瘤性质。结果显示,21例疑似病例被诊断为18例造血系统肿瘤和3例非造血系统肿瘤。18例造血系统肿瘤分别为5例急性淋巴细胞白血病(ALL),2例慢性淋巴细胞白血病(CLL),6例淋巴瘤,2例骨髓异常增生综合征(MDS)和3例急性粒细胞白血病(AML);3例非造血系统肿瘤均为肥大细胞瘤的骨髓转移,即肥大细胞白血病(MCL)。结果表明,临床采用血常规检查和血涂片分类计数可鉴定血液肿瘤患犬的细胞形态学异常,继之适应性应用骨髓细胞学技术辅助检查可确诊肿瘤的性质。因此,骨髓细胞学对犬血液肿瘤疾病的临床诊断具有重要辅助价值。 相似文献
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用马传染性贫血(EIA)病毒实验性感染的马共12匹,其骨髓用电镜进行观察,以明确增殖细胞的超微结构。在疾病早期。增殖性病变由五种免疫造血细胞组成:1) 原血细胞,2) 未成熟粒细胞造血细胞(原始粒细胞、早幼粗细胞,髓细胞),3) 未成熟红细胞造血细胞(红细胞原血细胞、中幼红细胞),4) 单核巨噬细胞系统细胞(幼单核细胞及其衍生细胞) 5) 浆细胞系细胞(浆细胞和浆母细胞)。未成熟粒细胞造血细胞是骨髓增生性病变的主要成分,尤其突出的是早幼粒细胞。该期增生性病变被看做是骨髓造血灶对EIA病毒感染的炎症反应和修复过程的反应。慢性期骨髓增生病变由二种主要类型的细胞组成:1) 中幼红细胞(成熟的中幼红细胞和晚幼红细胞),2) 小淋巴细胞(可能包括造血干细胞)。中幼红细胞围绕一个巨噬细胞形成一个“岛屿”是该期病变的主要成分,这种岛屿考虑是EIA病毒持续感染所致溶血而引起的红细胞造血灶的过度增生。建议EIA是一种淋巴—骨髓复合体疾病。 相似文献
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《黑龙江畜牧兽医》2016,(14)
猫白血病(Feline Leukaemia,FeL)是由猫白血病病毒(Feline Leukaemia Virus,FeLV)和猫肉瘤病毒(Feline sarcoma virus,FeSV)引起的一种恶性淋巴瘤病,主要引起猫肿瘤并造成免疫系统抑制,也可感染其他种类猫科动物。该病在世界上许多国家的猫中发生,发病率和死亡率都很高,是猫的一种严重传染病,90%以上感染猫终身带毒。文章主要介绍FeLV的流行病学及临床症状、诊断、治疗及预后。重点介绍了诊断方法,主要检测手段有血常规检查、血液生化检查、血清学检测、分子生物学检测,当前分子生物学检测检出率及准确率较高。 相似文献
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我们对南九洲玩赏猫中猫白血病病毒(FeLV)感染情况进行了调查,采用聚焦诱导测定法(EIA,focus inducing assay)测定血浆中猫白血病病毒、用中和试验(NT)检测抗猫白血病病毒A亚群的抗体。结果,3.8%的猫感染了猫白血病病毒,19.8%的猫测得有中和抗体。 相似文献
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Evidence for the non-involvement of the uterus in the lifespan of the corpus luteum in the cyclic dog 总被引:1,自引:0,他引:1
Progesterone levels in peripheral blood of dogs were analysed during the cycle in which hysterectomy (n = 5) or sham surgery (n = 3) was performed as well as during the cycle of dogs (n = 5) hysterectomized at least one year prior to this study; the data were compared with the findings in control dogs (n = 3). The averages of the duration of the luteal period observed in the three experimental groups were not significantly different from those of control dogs. Immediately after surgery, the progesterone level decreased from 25 to 50% of the presurgical level, but returned to presurgical level in about four days. Prolactin levels were elevated for about 30 h after surgery. Nevertheless, the averages of the mean prolactin levels for each animal during the luteal period of the experimental groups were not significantly different from those of control dogs. It is concluded that in the dog, the uterus is not involved in the lifespan of the cyclic corpus luteum. 相似文献
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Meschan EM Peham C Schobesberger H Licka TF 《Veterinary journal (London, England : 1997)》2007,173(3):578-584
As there is no statistical evidence that saddle fit influences the load exerted on a horse's back, this study was performed to assess the hypothesis that the width of the tree significantly alters the pressure distribution on the back beneath the saddle. Nineteen sound horses were ridden at walk and trot on a treadmill with three saddles differing only in tree width. Kinetic data were recorded by a sensor mat. A minimum of 14 motion cycles were used in each trial. The saddles were classified into four groups depending on fit. For each horse, the saddle with the lowest overall force (LOF) was determined. Saddles were classified as "too-narrow" if they were one size (2 cm) narrower than the LOF saddle, and "too-wide" if they were one size (2 cm) wider than the LOF saddle. Saddles two sizes wider than LOF saddles were classified as "very-wide". In the group of narrow saddles, the pressure in the caudal third (walk 0.63 N/cm(2)+/-0.10; trot 1.08 N/cm(2)+/-0.26) was significantly higher compared to the LOF saddles (walk 0.50 N/cm(2)+/-0.09; trot 0.86 N/cm(2)+/-0.28). In the middle transversal third, the pressure of the wide saddles (walk 0.73 N/cm(2)+/-0.06; trot 1.52 N/cm(2)+/-0.19) and very-wide saddles (walk 0.77 N/cm(2)+/-0.06; trot 1.57 N/cm(2)+/-0.19) was significantly higher compared to LOF saddles (walk 0.65 N/cm(2)+/-0.10/ 0.63 N/cm(2)+/-0.11; trot 1.33 N/cm(2)+/-0.22/1.27 N/cm(2)+/-0.20). This study demonstrates that the load under poorly fitting saddles is distributed over a smaller area than under properly fitting saddles, leading to potentially harmful pressures peaks. 相似文献
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嗅源是军犬嗅觉作业训练的依据.军犬鉴别中嗅源能力的培养在整个鉴别训练中占有重要地位,关系到鉴别训练的成败和鉴别能力的提高.所以,军犬在嗅认嗅源时必须按照训犬员的指令充分、细致地感受嗅源气味,并且对嗅源气味产生兴奋反应.如何培养军犬充分嗅认嗅源以及及时解决嗅认过程中出现的问题,成为我们进行鉴别训练的关键.…… 相似文献
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Observations on the Pathology of the Spleen of the Cat 总被引:1,自引:0,他引:1
Abstract— Lesions were found in the spleen of four of sixty-three cats examined post mortem in the department, and comprised two examples of lymphosarcoma, one of chronic fibrinous peritonitis and one of subcapsular haematoma. Abnormalities were found in two cat spleens received from veterinary surgeons in general practice. In one cat the abnormalities were an haemangiosarcoma with secondary deposits in the liver and in the other extensive mast cell infiltration. In addition lesions were detected in the spleen of three of eighty-seven cats examined post mortem in general practice. The lesions were: multiple secondary deposits of adenocarcinoma from a primary tumour of the mammary gland, a ruptured spleen and a foreign body below the splenic capsule. Résumé— L'examen microscopique de soixante-trois chats pratiqué dans le service a permis de rencontrer quatre fois des lésions de la rate, dont deux lymphosarcomes, une péritonite capsulaire fibrineuse et un hématome sous-capsulaire. D'autre part des lésions ont été trouvées dans deux rates de chat expédiées par des vétérinaires exerçant en pratiaue générale. Chez un chat il s'agissait d'un htmangiosarcome avec métastases hépatiques et chex l'autre d'une infilt ation diffuse par des mastocyta. De plus, on a rencontré des llésions dnas la rate de trois chats parmi quatre-vingt sept autopsies effectuées dans le cadre d'une clientèle génárale. Ces iésions étaient dés métastases multiples d'un adénocarcinome dont la tumeur primitive siègeait dam la glande mammaire, une rupture de la rate et un corps érangers sou capsulaire. Zusammenfassung— Läsionen der Milz wurden bei vier von dreiuiidsechzig in dieser hbteilung sezierten Katzen gefunden, und zwar in zwei Fällen ein Lymphosarkom, in einem Falle eine chron-ische fibrinöse Peritonitis und in einem ein subkapsuläres Hématom. Anomalien fanden sich auch in der Milz von zwei Katzen, die aus der tierxrztlichen Praxis eingesandt wurden. Bei der einen Katze war dies ein Hämangiosarkom mit Metastasen in der Leber, bei der anderen eine weitläufige Infiltration der Mastzellen. Außerdem wurden bei drei von siebenundachtzig in der Praxis sezierten Katzen Milzläsionen gefunden. Diese bestanden am multiplen Metastasen eines Adenokarzinoms der Brustdrüse, einer Milzzerreissung und einem Fremdkörper unterhalb der Milzkapsel. 相似文献