虎巴氏杆菌病病例

多杀性巴氏杆菌（Pasteurllosis multocida）可感染多种畜禽、皮毛动物、野生动物和野禽，引起发病和死亡，对畜牧业生产、皮毛动物养殖和野生动物保护危害严重。在我国，黑熊、小熊猫、豺、狼、麝鼠、鹿、斑马、水貂、蓝狐和孔雀均有发病死亡的报道，国内外未见有虎发生巴氏杆菌病的报道。2004年7月至8月问，我国某动物园养殖的3只东北虎发生急性死亡，经临床观察、病理剖检、细菌分离、动物实验和生化试验，确诊为多杀性巴氏杆菌感染。     

虎群酚消毒剂中毒的病案分析

1997年10月间，某野生动物养殖场的虎群发生了一种以严重肺损害，临床表现为呼吸困难，最后死于呼吸麻痹的疾病。先后作出犬瘟热、猫瘟、锥虫病、巴氏杆菌病的疑似诊断；最后经作者诊断为酚消毒剂中毒病。现将病情分析及诊疗经过报告如下：l病的发生与诊疗误导该虎场饲养有东北虎和孟加拉虎。1997年10月初，先是回头体弱的母虎和1只仔虎发病后死亡，接着在10天内虎连续发病。在第3只病虎死亡之后，请兽医会诊。A兽医站诊断为“锥虫病”，虎场主管人员不予相信，循着报纸上有过的报导，某动物园饲养的虎1996年曾发生过犬瘟热，于是根据某动…     

亚成体东北虎感染巴氏杆菌死亡一例

2009年1月11日,北方森林动物园发生一起自繁自养的亚成体东北虎感染巴氏杆菌死亡病例。本病例从发病到死亡共5 d时间,病程较短,以食欲下降至废绝,饮水量不变,精神沉郁,口腔腺体分泌增多、流涎,呈滴水样,腹部疼痛感明显为特征,口服诺氟沙星和多酶片治疗无效后改用肌注头孢哌酮钠和庆大霉素治疗,3 d后出现神经症状抽搐死亡。剖检肝脏表面有大量的针尖大小黄白色点状坏死灶。根据临床症状、病理剖检和实验室检查,确诊为巴氏杆菌感染。     

猪牛同发急性巴氏杆菌病的诊治报告

猪、牛巴氏杆菌病是由多杀性巴氏杆菌引起的一种急性传染病．临床上，猪巴氏杆菌病称为猪肺疫，常呈急性败血型和慢性胸膜炎症状；牛巴氏杆菌病称牛出败，常呈败血型，水肿型和胸型症状．近年来，我区猪、牛巴氏杆菌病常零星散发，有时两者同时发生，呈地方性流行的较少见．１９９７年５月底，病区某村牲猪发生一种以体温升高，急性败血型症状，呼吸困难为主要症状的流行性疾病，共发病２７０头、死亡２００头、死亡率为７４％、７月初，该村耕牛又相继发生一种呈急性败血型、体温高、死亡快的流行性疾病．一周内发病１０头，死亡５头，死亡…     

兔巴氏杆菌病的综合防治

兔巴氏杆菌又名兔出血性败血病，是由多杀性巴氏杆菌引起的一种急性、热性传染病。急性病例以败血症和出血性炎症为主要特征，慢性病例以传染性鼻炎、地方流行性肺炎、中耳炎、结膜炎、子宫积脓、睾九炎和脓肿为主要特征。家兔对本病非常敏感，一般不分品种和年龄均易感染，常引起大批发病和死亡。吉林省双辽市某养殖户饲养品种兔５１２只，发病４７７只，死亡３３５只。经诊断确诊为免巴氏杆菌病。急性型死亡３０５只，多为仔免和青年免；慢性型死亡３０只，多为种兔；其余病兔１７２只经治疗有１４９只症状消失；还有２３只正在治疗。该户…     

洱源县一起黄牛巴氏杆菌病的诊治与体会

牛巴氏杆菌病是一种热性、急性、败血性传染病,在饲养管理不良或遇到恶劣环境时会引起发病。洱源县西山乡立坪村发生一起放养黄牛出现不明原因死亡病例,通过流行病学调查、临床症状观察、病理剖检和病原分离鉴定,确诊为牛巴氏杆菌病,经及时采取综合防控措施,控制了该病的流行。     

猪肺疫的诊断及病理形态学观察

猪肺疫又称猪巴氏杆菌病或出血性败血症,是由多杀性巴氏杆菌引起的猪的一种急性、热性传染病。最急性型与急性型可导致猪只大批量死亡。对门诊接诊的患病猪进行了一般临床诊断、病原学检测和病理组织学观察,确诊为猪肺疫。并对此病的病因、发病机理、诊断和治疗方法等进行了探讨。     

肉兔暴发巴氏杆菌病的诊疗报告

兔巴氏杆菌为一条件性致病菌。通常多因气候变化，环境条件恶劣，卫生条件较差，饲养管理不良，以及兔体制较弱、抗病力下降，病菌大量繁殖，从而引起巴氏杆菌病暴发流行。1999年3月24日，忻州市某养兔场所养的1200只新西兰肉兔相继发病，3d内发病兔达460只，发病率为30.83％；死亡189只，死亡率为15.75%,致死率为41.09%,经诊断为兔巴氏杆菌病,采用综合防制措施后,病情迅速得到控制,再无新的病例和死亡发生,现报道如下。     

马鹿巴氏杆菌病的诊疗

马鹿巴氏杆菌病的诊疗邹洪涛，马民，刘术江（内蒙古赤峰市巴林左旗乌兰坝林场，０２５４６２）１９７９年１０月，我场饲养的梅花鹿曾发生巴氏杆菌病，死亡４只（２公２母）；１９８８年６月又发生，死亡４只（１公３母）；１９９４年６月２１日至７月下旬，又一次暴发。...     

1例小尾寒羊巴氏杆菌病的诊洽

巴氏杆菌病是由多杀性巴氏杆菌引起的多种畜禽及野生动物的一种传染病的总称。羊巴氏杆菌病又称羊出血性败血病。其特征为高热，皮下有浆液浸润点状出血，胸腔内有黄色渗出物；肺出血、淤血部分有肝变特征；胃肠黏膜出血；脾肿大，其它脏器水肿和淤血。     

白术、微米白术和白术多糖对断奶仔猪生长性能和肠道形态及微生态区系的影响

试验选用96头平均体重14.82 kg左右的杜×长×大断奶仔猪,随机分成4组,每组3栏,每栏8头(公母各半)。对照组饲喂基础日粮,试验1、2、3组分别添加1%80目白术、0.2%白术多糖和1%微米白术。试验期30 d。结果表明:在生长性能方面,与对照组相比,1%微米白术添加组可显著提高日增重(P0.05)、降低饲料增重比和腹泻率,而且效果优于1%80目白术组和0.2%白术多糖组,在肠道形态和肠道微生态区系方面,与对照组相比,日粮添加1%80目白术、0.2%白术多糖、1%微米白术均可不同程度的提高十二指肠和空肠的绒毛高度,加深十二指肠和空肠的隐窝深度,并且增加肠道微生态区系的多样性,其中以1%微米白术添加组的效果最佳。     

Prevalence and seasonal incidence of nematode parasites and fluke infections of sheep and goats in eastern Ethiopia

Sissay, M.M., Uggla, A. and Waller, P.J., XXXX. Prevalence and seasonal incidence of nematode parasites and fluke infections of sheep and goats in eastern Ethiopia. Tropical Animal Health and Production, XXXX. A 2-year abattoir survey was carried out to determine the prevalence, abundance and seasonal incidence of gastro-intestinal (GI) nematodes and trematodes (flukes) of sheep and goats in the semi-arid zone of eastern Ethiopia. During May 2003 to April 2005, viscera including liver, lungs and GI tracts were collected from 655 sheep and 632 goats slaughtered at 4 abattoirs located in the towns of Haramaya, Harar, Dire Dawa and Jijiga in eastern Ethiopia. All animals were raised in the farming areas located within the community boundaries for each town. Collected materials were transported within 24 h to the parasitology laboratory of Haramaya University for immediate processing. Thirteen species belonging to 9 genera of GI nematodes (Haemonchus contortus, Trichostrongylus axei, T. colubriformis, T. vitrinus, Nematodirus filicollis, N. spathiger, Oesophagostomum columbianum, O. venulosum, Strongyloides papillosus, Bunostomum trigonocephalum, Trichuris ovis, Cooperia curticei and Chabertia ovina), and 4 species belonging to 3 genera of trematodes (Fasciola hepatica, F. gigantica, Paramphistomum {Calicohoron} microbothrium and Dicrocoelium dendriticum) were recorded in both sheep and goats. All animals in this investigation were infected with multiple species to varying degrees. The mean burdens of adult nematodes were generally moderate in both sheep and goats and showed patterns of seasonal abundance that corresponded with the bi-modal annual rainfall pattern, with highest burdens around the middle of the rainy season. In both sheep and goats there were significant differences in the mean worm burdens and abundance of the different nematode species between the four geographic locations, with worm burdens in the Haramaya and Harar areas greater than those observed in the Dire Dawa and Jijiga locations. Similar seasonal variations were also observed in the prevalence of flukes. But there were no significant differences in the prevalence of each fluke species between the four locations. Overall, the results showed that Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Fasciola and Paramphistomum species were the most abundant helminth parasites of sheep and goats in eastern Ethiopia.     

Internal Parasites and Haematological Values in Cattle Slaughtered in Buea Subdivision of Cameroon

Tropical Animal Health and Production -     

Phase I evaluation of CCNU (lomustine) in tumor-bearing cats

1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.     

Chemotaxis of macrophage in inflammation

Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.     

Prevalence of gastric lesions in racing Alaskan sled dogs

Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.     

Furosemide continuous rate infusion in the horse: evaluation of enhanced efficacy and reduced side effects

Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.     

Y‐chromosomal variation of local goat breeds of Turkey close to the domestication centre

Genetic variations in chromosome Y are enabling researchers to identify paternal lineages, which are informative for introgressions and migrations. In this study, the male‐specific region markers, sex‐determining region‐Y (SRY), amelogenin (AMELY) and zinc finger (ZFY) were analysed in seven Turkish native goat breeds, Angora, Kilis, Hair, Honaml?, Norduz, Gürcü and Abaza. A SNP in the ZFY gene defined a new haplotype Y2C. All domestic haplogroups originate from Capra aegagrus, while the finding of Y1A, Y1B, Y2A and Y2C in 32, 4, 126 and 2 Turkish domestic goats, respectively, appears to indicate a predomestic origin of the major haplotypes. The occurrence of four haplotypes in the Hair goat and, in contrast, a frequency of 96% of Y1A in the Kilis breed illustrate that Y‐chromosomal variants have a more breed‐dependent distribution than mitochondrial or autosomal DNA. This probably reflects male founder effects, but a role in adaptation cannot be excluded.     

Changes in proportion of canine urinary calculi composed of calcium oxalate or struvite in specimens analyzed from 1981 through 2001

The objective of this report was to characterize 20-year changes in proportion of calcium oxalate (CaOx) calculi and struvite calculi in dogs, and associations with breed, age, and sex. In this retrospective study, results of analysis of urinary calculi from dogs were reviewed for specimens received between July 1, 1981, and December 31, 2001. Breed, sex, age, year of submission of the specimen, and mineral type(s) were analyzed statistically. CaOx or Struvite or both were contained in 18,966 of 20,884 (91%) specimens. For both sexes, a 20-year statistically significant increase was observed in the proportion of calculus specimens that contained CaOx. The increase in this proportion was greater in females (1% to 31%) than in males (18% to 82%). From 1998 to 2001, when proportions may have plateaued, the odds of specimens containing CaOx were markedly higher in 18 breeds, markedly lower in 5 breeds, and not significantly different in 13 breeds compared with crossbreds. For both sexes, a 20-year statistically significant decrease was observed in the proportion of calculus specimens that contained struvite. This decrease in proportion was greater for males (79-16%) than for females (97-68%). From 1998 to 2001, when proportions plateaued, the odds of calculi containing struvite were markedly lower in 20 breeds, markedly higher in 1 breed, and not significantly different in 15 breeds when compared with crossbreds. Breed, age, and sex were associated statistically with CaOx or struvite urolithiasis. In conclusion, there appears to have been a long-term increase in the proportion of specimens of canine urinary calculi that contain CaOx as well as a long-term decrease in the proportion of specimens of calculi that contain struvite for both male and female dogs. The rate of change appeared to begin leveling off in the period 1998 to 2001. The recent proportion of dogs with either CaOx- or struvite-associated urolithiasis may depend on breed, age, and sex, and on interactions among these 3 factors.     

Smart Phone Assisted City-scale Wireless Sensor Network Deployment for Transportation System Monitoring

<正>1.INTRODUCTION Ensuring transportation network security is one Of the most daunting challenges confronting homeland security agencies today.Significant research has been dedicated.To model and analyze the vulnerability of transportation systems,while notably fewer studies propose specific strategies for deploying defensive technologies to safeguard these systems.