| NRAMP1基因的研究进展 |
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| 引用本文： | 薛尚军,贾静敏,刘宏,石建中,曹果清. NRAMP1基因的研究进展[J]. 畜牧与饲料科学, 2011, 32(1): 28-30 |
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| 作者姓名： | 薛尚军 贾静敏 刘宏 石建中 曹果清 |
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| 作者单位： | 1. 山西省大同市种猪场,山西,大同,037000
2. 山西农业大学动物科技学院,山西,太谷,030801 |
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| 基金项目： | 山西省攻关项目，科技部农业科技成果转化资金项目 |
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| 摘 要： | 天然抗性相关巨噬蛋白(natural resistance associated macrophage protein 1,NRAMP1)与多种胞内菌如结核分枝杆菌、沙门氏杆菌和利什曼原虫等易感和抗性相关。综述了NRAMP1基因的结构特点、作用机理、表达调控及其与疾病的相关性,以期为应用于猪的抗病育种提供理论依据。
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| 关 键 词： | NRAMP1基因 结构特点 作用机理 表达调控 |
The Progress of Natural Resistance Associated Macrophage Protein 1 |
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| XUE Shang-jun,JIA Jing-min,LIU Hong,SHI Jia-zhong,CAO Guo-qing. The Progress of Natural Resistance Associated Macrophage Protein 1[J]. Animal Husbandry and Feed Science, 2011, 32(1): 28-30 |
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| Authors: | XUE Shang-jun JIA Jing-min LIU Hong SHI Jia-zhong CAO Guo-qing |
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| Affiliation: | XUE Shang-jun1,JIA Jing-min2,LIU Hong1,SHI Jia-zhong1,CAO Guo-qing2(1.Datong Pig Breeding Farm,Datong 037000,China,2.College of Animal Science and Veterinary Medicine,Shanxi Agricultural University,Taigu 030801,China) |
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| Abstract: | Natural resistance associated macrophage protein 1 has been testified that it is correlation to resistance on a variety of intracellular bacteria such as Mycobacterium tuberculosis,Salmonella and Leishmania etc.In this paper,the structure characteristics of NRAMP1 gene,expression mechanism,regulation and correlation with disease was reviewed,it will provide the theoretical basis for breeding application in pig disease resistance. |
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| Keywords: | NRAMP1 gene structure characteristics mechanism regulation and expression |
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