Von Wille-brand's disease in UK dober-manns: Possible correlation of a polymorphic DNA marker with disease status |
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| Authors: | N G Holmes S C Shaw H F Dickens L M Coombes E J Ryder J D Littlewood M M Binns |
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| Institution: | Centre for Preventive Medicine, Animal Health Trust, PO Box 5, Newmarket, Suffolk CB8 7DW;*Centre for Small Animal Studies, Animal Health Trust, PO Box 5, Newmarket, Suffolk CB8 7DW |
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| Abstract: | Ninety-one dobermanns have been typed for a polymorphic microsatellite DNA marker situated within an intron of the von Willebrand factor gene and the alleles correlated with von Wille-brand's disease status. Two alleles were identified, one associated only with the normal gene and the other with both normal and disease genes. |
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