| 微孢子虫蛋白质及其与宿主互作的研究进展 |
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| 引用本文： | 吴正理,李艳红,宋元达.微孢子虫蛋白质及其与宿主互作的研究进展[J].蚕业科学,2009,35(4). |
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| 作者姓名： | 吴正理 李艳红 宋元达 |
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| 作者单位： | 1. 中南大学生物科学与技术学院生物化学系,长沙,410013
2. 中南大学湘雅医学院医学检验系,长沙,410013 |
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| 基金项目： | 中南大学人才引进启动基金 |
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| 摘 要： | 微孢子虫(protozoan:microsporidia)是一类细胞内专性寄生的单细胞真核生物,可广泛寄生于几乎所有的动物。早期对微孢子虫的研究主要集中在对其种类的分离鉴定方面,随着大规模基因组测序的不断深入,极大地推动了微孢子虫的研究,尤其是微孢子虫具有独特的进化地位以及基因组、细胞器和物质能量代谢途径等简化进化的特点,使其成为当前研究的热点。综述了该领域近10年来在微孢子虫总蛋白组成成分分析、极丝蛋白和孢壁蛋白的分离鉴定,以及孢壁蛋白与宿主的相互作用等方面的研究进展,并简要概述了该领域研究存在的问题及后续研究课题。
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| 关 键 词： | 微孢子虫 极丝蛋白 孢壁蛋白 宿主 |
Advances in the Research of Microsporidian Proteins and Their Interactions With Host Cells |
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| WU Zheng-Li,LI Yan-Hong,SONG Yuan-Da.Advances in the Research of Microsporidian Proteins and Their Interactions With Host Cells[J].Acta Sericologica Sinica,2009,35(4). |
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| Authors: | WU Zheng-Li LI Yan-Hong SONG Yuan-Da |
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| Institution: | WU Zheng-Li1 LI Yan-Hong2 SONG Yuan-Da1(1Department of Biochemistry,School of Biological Science , Technology,Central South University,Changsha 410013,China,2Department of Medical Inspection,Xiangya Medical School,China) |
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| Abstract: | Microsporidia are unicellular eukaryotes found in a wide variety of animal hosts as obligate intracellular parasites.Early studies on microsporidia had been mainly focused on isolation and identification of new species.As more and more genome sequencing projects were completed,the researches on microsporidia have been further promoted.Microsporidia became a hot research area because of its unique phylogenetic position and its largely reduced genome size and simplified cellular organelles and metabolic pathw... |
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| Keywords: | Microsporidia Polar tube protein Spore wall protein Host |
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