Clinical application of 2.16% hypertonic saline solution to correct the blood sodium concentration in diarrheic calves with
hyponatremia |
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| Authors: | Mitsuhide NAKAGAWA Kenji TSUKANO Yoshiki MURAKAMI Marina OTSUKA Kazuyuki SUZUKI Hiroetsu SUZUKI |
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| Affiliation: | 1)Hokushin Veterinary Medical Center, Nagano Prefectural Federation of Agricultural Mutual Aid Association, 1-4-28 Miyoshicho, Nagano, Nagano 383-0025, Japan;2)School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunnkyoudai, Ebetsu, Hokkaido 069-8501, Japan;3)School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyounancho, Musashino, Tokyo 180-0023, Japan |
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| Abstract: | The aim of this study was to examine whether 2.16% hypertonic saline solution (HSS) is useful for the treatment of diarrheic calves with hyponatremia. Eleven of 13 female Holstein calves exhibiting moderate diarrhea and hyponatremia received 1,250 ml of 2.16% HSS over 15 min regardless of body weight. The remaining two calves that were unable to stand and had severe hyponatremia received 2,500 ml of 2.16% HSS intravenously over 30 min. As a result, hyponatremia in all diarrheic calves was significantly improved by the administration of 2.16% HSS from 122.2 ± 7.0 mEq/l at pre to 134.8 ± 3.7 mEq/l at post, which was above the threshold of 132 mEq/l for hyponatremia. Therefore, 2.16% HSS may be useful for hyponatremia in calves with diarrhea. |
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| Keywords: | 2.16% hypertonic saline solution calf diarrhea hyponatremia |
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