| ETEC多价定居因子对仔猪大肠杆菌病的预防试验 |
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| 引用本文： | 李学伍,张改平,阎玉河,邓瑞广,杨艳艳,王爱萍,李青梅.ETEC多价定居因子对仔猪大肠杆菌病的预防试验[J].华北农学报,2001,16(2):127-131. |
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| 作者姓名： | 李学伍 张改平 阎玉河 邓瑞广 杨艳艳 王爱萍 李青梅 |
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| 作者单位： | 河南省农业科学院生物技术研究所, |
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| 基金项目： | 河南省九五科技攻关项目(961040202) |
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| 摘 要： | 应用分子免疫学理论 ,将定居因子K88,K99,987P ,F4 1与其特异受体结合 ,封闭肠粘膜上皮细胞的受体 ,阻断致病菌的定居因子与肠粘膜上皮细胞特异受体的结合 ,使致病菌无法定居。试验结果显示 ,其仔猪攻毒保护率为 10 0 % ,预防试验保护率为 10 0 % ,可以有效控制仔猪大肠杆菌的发生 ,为该病的现有预防模式增添了新的内容
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| 关 键 词： | 仔猪 致病性大肠杆菌 定居因子 预防 |
| 文章编号： | 1000-7091(2001)02-0127-05 |
| 修稿时间： | 2000年1月24日 |
Protection Against Piglets Colibacillosis with Polyvalent Resident Factors of Enterotoxigenic Escherichia Coli |
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| LI Xuewu,ZHANG Gaiping,YAN Yuhe,DENG Ruiguang,Yang Yanyan,Wang Aiping,Li Qingmei.Protection Against Piglets Colibacillosis with Polyvalent Resident Factors of Enterotoxigenic Escherichia Coli[J].Acta Agriculturae Boreali-Sinica,2001,16(2):127-131. |
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| Authors: | LI Xuewu ZHANG Gaiping YAN Yuhe DENG Ruiguang Yang Yanyan Wang Aiping Li Qingmei |
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| Abstract: | The resident factors K88,K99,987P and F41 had been combined with the specific receptors of the intestinal mucosa epithelial cells under the molecular immunoreaction,and the specific receptors had been blocked.The receptors blocked by resident factors couldn′t attach the resident factors,and prevented the enterotoxigenic E.coli settling down the intestine.The results showed that the piglets infected protection rate was 100%,preventive protection rate was 100%.The experiments proved that the method was effective measures against piglets colibacillosis,and added new content to preventive model at present. |
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| Keywords: | Piglets Enterotoxigenic E coli Resident factors Prevention |
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