Myofibroblastic sarcoma of the pleura in a pig |
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Authors: | Kubota Y Ishikawa Y Shibahara T Kadota K |
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Institution: | Higashihiroshima Livestock Hygiene Service Center, Japan. |
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Abstract: | An intrathoracic sarcoma from a 7-month-old female pig was studied by light and electron microscopy and immunohistochemistry. The tumor tissue of varied cell density consisted chiefly of spindle-shaped cells, some of which grew around blood vessels in a concentric fashion. Many tumor cells were positive for alpha smooth muscle actin and not for desmin, though some cells were reactive for both antigens. A majority of tumor cells had ultrastructural features characteristic of myofibroblasts, but a few cells resembled vascular smooth muscle cells in the synthetic state. This neoplasm may have arisen from vascular smooth muscle with features indicating a transition to myofibroblasts. |
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