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| MC1R基因的研究进展 | |
| 引用本文： | 封竣淇,徐伟,黄兰,罗卫星,蔡惠芬. MC1R基因的研究进展[J]. 中国畜牧兽医, 2017, 44(4): 1141-1148. DOI: 10.16431/j.cnki.1671-7236.2017.04.029 |
| 作者姓名： | 封竣淇 徐伟 黄兰 罗卫星 蔡惠芬 |
| 作者单位： | 1. 贵州大学, 高原山地动物遗传育种与繁殖省部共建教育部重点实验室, 贵阳 550025; 2. 贵州省动物遗传育种与繁殖重点实验室, 贵州大学动物科学学院, 贵阳 550025 |
| 基金项目： | 贵州省科技富民强县专项行动计划"优质沿河白山羊提纯复壮"[2014] 5202-1号；贵州省科技厅2013年省市县科技合作项目"贵州白山羊选育示范与推广"[2013001] |
| 摘 要： | MC1R基因作为控制毛色的重要候选基因之一，不仅在黑色素合成过程中起着重要的调控作用，参与毛色的形成，还对人畜疾病、生长性状、行为有着不同程度的影响，因而引起相关学者的广泛关注。为加深对MC1R基因的认识和了解，作者对MC1R基因结构、功能、作用机理、基因的定位、多态性检测及其在人畜方面的研究进展进行综述，并提出新的设想。 |
| 关 键 词： | MC1R基因 毛色 作用机理 功能 |
| 收稿时间： | 2016-10-13 |
Research Advances on MC1R Gene |
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| FENG Jun-qi,XU Wei,HUANG Lan,LUO Wei-xing,CAI Hui-fen. Research Advances on MC1R Gene[J]. China Animal Husbandry & Veterinary Medicine, 2017, 44(4): 1141-1148. DOI: 10.16431/j.cnki.1671-7236.2017.04.029 | |
| Authors: | FENG Jun-qi XU Wei HUANG Lan LUO Wei-xing CAI Hui-fen |
| Affiliation: | 1. Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang 550025, China; 2. Guizhou Key Laboratory of Animal Genetic, College of Animal Science, Guizhou University, Guiyang 550025, China |
| Abstract: | MC1R gene, as one of the important candidate genes for controlling coat color, not only plays an important role in the process of melanin synthesis, but also participates in the formation of coat color and also has different effects on human and animal diseases, growth traits and behaviors. The study of MC1R gene has attracted the attention of scholars.In order to deepen the understanding of MC1R gene, the structure, function, mechanism, gene locus, polymorphism analysis and research progress of human and animal of MC1R gene were reviewed and new ideas were put forward in this review. |
| Keywords: | MC1R gene coat color mechanism function |
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