| 冠状病毒受体的研究进展 |
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| 引用本文： | 袁一心,赵福杰,张驰,胡慧. 冠状病毒受体的研究进展[J]. 畜牧与兽医, 2021, 0(3): 142-147 |
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| 作者姓名： | 袁一心 赵福杰 张驰 胡慧 |
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| 作者单位： | 河南农业大学牧医工程学院;河南省动物性食品安全重点实验室 |
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| 基金项目： | 国家自然科学基金面上项目(31772773);国家自然科学基金NSFC-河南联合重点项目(U1704231)。 |
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| 摘 要： | 近年来多种感染人或家畜的冠状病毒病轮番出现,给人类社会的经济和公共卫生安全带来很大危害.特别是在2019年底出现并在全球迅速蔓延的SARS-CoV-2,由此引发的新型冠状病毒肺炎(COVID-19)在2019年12月至2020年3月之间在全球范围内造成超过7万人死亡.冠状病毒感染宿主的第一步是识别宿主细胞膜受体分子并与...
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| 关 键 词： | 冠状病毒 病毒受体 公共卫生安全 |
Advances in research on the receptor of coronavirus |
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| YUAN Yixin,ZHAO Fujie,ZHANG Chi,HU Hui. Advances in research on the receptor of coronavirus[J]. Animal Husbandry & Veterinary Medicine, 2021, 0(3): 142-147 |
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| Authors: | YUAN Yixin ZHAO Fujie ZHANG Chi HU Hui |
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| Affiliation: | (College of Animal Science and Veterinary Medicine,Henan Agricultural University,Zhengzhou 450046,China;Key Laboratory for Animal-derived Food Safety of Henan Province,Zhengzhou 450046,China) |
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| Abstract: | In recent years,many types of coronavirus infection in both humans and animals have been recurring,which has posed great threats to global economy and public health security.SARS-CoV-2,detected in late 2019,has rapidly spread worldwide,causing a COVID-19 pandemic.The pandemic has claimed over 70000 lives in the period from Dec 2019 through Mar 2020.The coronavirus infection starts with recognition of and binding to the receptor on the host cell membrane,and then the virus will invade the host cell with the SARS-CoV-2 genome.Therefore,elucidation of coronavirus cellular receptors is of great significance for understanding the host and tissue tropism of the virus.Meanwhile,it will be helpful in understanding its pathogenic and transmission mechanism,and pave the way for anti-viral treatment of COVID-19.In this article,the latest progresses in research on the receptors of coronavirus in recent years,including ACE2,APN,DPP4,SA and CEACAM1,will be introduced and reviewed. |
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| Keywords: | coronavirus virus receptor pubic health security |
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