| 动物支原体相关蛋白的免疫原性研究进展 |
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| 引用本文： | 陈胜利,郝华芳,季文恒,储岳峰. 动物支原体相关蛋白的免疫原性研究进展[J]. 畜牧兽医学报, 2021, 52(5): 1230-1237. DOI: 10.11843/j.issn.0366-6964.2021.05.009 |
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| 作者姓名： | 陈胜利 郝华芳 季文恒 储岳峰 |
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| 作者单位： | 中国农业科学院兰州兽医研究所 家畜疫病病原生物学国家重点实验室, 兰州 730046 |
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| 基金项目： | 国家重点研发计划项目（2017YFD0500905）；甘肃省重点研发计划项目（18YF1NA130） |
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| 摘 要： | 动物支原体可引起肺炎、关节炎、乳腺炎等一系列重要疾病,临床上常表现为慢性、持续性感染,给养殖业造成严重的经济损失.亚单位疫苗具有安全高效、成本低廉等优点,是支原体疫苗研究的重要发展方向.本文主要介绍了重要动物支原体相关蛋白的免疫原性研究进展,以期为今后动物支原体病亚单位疫苗研究提供参考.
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| 关 键 词： | 动物支原体 支原体 蛋白 免疫原性 亚单位疫苗 免疫蛋白 |
| 收稿时间： | 2020-06-05 |
Research Advances in Immunogenicity of Related Proteins of Animal Mycoplasmas |
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| CHEN Shengli,HAO Huafang,JI Wenheng,CHU Yuefeng. Research Advances in Immunogenicity of Related Proteins of Animal Mycoplasmas[J]. Chinese Journal of Animal and Veterinary Sciences, 2021, 52(5): 1230-1237. DOI: 10.11843/j.issn.0366-6964.2021.05.009 |
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| Authors: | CHEN Shengli HAO Huafang JI Wenheng CHU Yuefeng |
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| Affiliation: | State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China |
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| Abstract: | Animal mycoplasmas contribute to some important diseases including pneumonia, mastitis, and arthritis, characterized by chronic and persistent infection, which causes serious economic losses to the breeding industry. Subunit vaccine has the advantages of safety, high efficiency, low cost, etc. It is an important direction of mycoplasma vaccine research. This paper describes the research advances in immunogenicity of related proteins of important animal mycoplasmas. It would be helpful to provide references for research of subunit vaccine of animal mycoplasmas. |
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| Keywords: | animal mycoplasmas mycoplasma protein immunogenicity subunit vaccine immune proteins |
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