LFA_3对大鼠血脂水平的影响

为观察 LFA_3对大鼠血脂的影响,将24只 Wistar 雄性大鼠等分成两组.试验组喂含10%LFA,的饲料8周,对照组不予处理.试验结果表明:试验组与对照组相比,总耗料量基本相同,平均体增重下降29.98%;腹脂重和肾脂肪囊重分别下降24.5%和23.01%:饲料报酬下降30.31%;血清总胆固醇含量下降23.45%;血清高密度脂蛋白胆同醇升高7.09%;血清甘油三酯无变化。提示:LFA_3有降低大鼠体内饲料转化和脂肪沉积、降低血清总胆固醇和升高血清高密度脂蛋白胆固醇作用。本文还对 LFA_3降脂作用的机理进行了探讨.

EFFECTS OF LFA_3 ON SERUM LIPID LEVEL IN RATS

To investigate the effect of LFA_3 on serum lipid Ievel,24 male Wistar rats were divided equally into two groups.Experimental group was fed with diets containing 10% LFA_3 for 8 weeks and control group was not dosed.The results showed that as compared with control group feed consumption and serum triglyceride of experimental group had no variation,but body weight gain,abdominal fat weight,kidney fat,feed efficinecy and serum cholesterol were decreased by 29.89%,24.5%,23.01%,30.31% and 23.45% respectively,and serum high density lipoprotein cholesterol HDL-C was increased by 7.09%.These revealed that LFA_3 had the actions to decrease feed conversion and fat deposition to reduce serum cholesttrol,and to cnhanec HDL-C in vivo.The mechanism of LFA_3 lowing fat was dis- cussed in the paper.