Ventricular systolic dysfunction in dogs diagnosed with hypoadrenocorticism |
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| Institution: | 1. Bluepearl Veterinary Partners, 4126 Packard Road, Ann Arbor, Michigan, 48108, USA;2. Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, 736 Wilson Road, East Lansing, Michigan, 48824, USA;1. Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, 4474 TAMU, College Station, TX 77843-4474, USA;2. Department of Population Health Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, 205 Duck Pond Dr, Blacksburg, VA 24061, USA;1. Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, 204 Duck Pond Drive, Blacksburg, VA 24061-0442, USA;2. Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA;3. Department of Veterinary Sciences, University of Parma, Strada del Taglio 10, 43126 PR, Italy;4. Department of Clinical Science, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Science, Box 7054, Uppsala, Sweden;5. CVCA Cardiac Care for Pets, 1209 Cromwell Bridge Road, Towson, MD 21286, USA;6. CVCA Cardiac Care for Pets, 165 Fort Evans Road NE, Leesburg, VA 20176, USA;2. Department of Veterinary Sciences, University of Parma, Strada del Taglio, 10, 43126, Parma, Italy;1. AniCura Specialistisch Verwijscentrum Haaglanden, Frijdastraat 20a, Rijswijk, 2288 EZ, the Netherlands;2. Veterinaire Specialisten Vught, Reutsedijk 8a, Vught, 5264 PC, the Netherlands;1. Clinica Veterinaria Malpensa, AniCura, Viale Marconi, 27, 21017, Samarate, VA, Italy;2. Ospedale Veterinario I Portoni Rossi, AniCura, Via Roma 57, 40069, Zola Predosa, BO, Italy;3. Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, 40064, Ozzano Dell''Emilia, BO, Italy;4. Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, 930 Campus Road, 14853, Ithaca, NY, USA |
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| Abstract: | In human patients with hypoadrenocorticism, a secondary dilated cardiomyopathy is noted that has been reported to resolve with replacement steroid therapy. A similar secondary dilated cardiomyopathy in dogs with hypoadrenocorticism has not been previously described. We present three dogs concurrently diagnosed with hypoadrenocorticism and ventricular dilation with systolic dysfunction. Two dogs were presented with clinical signs consistent with biventricular congestive heart failure and a third dog was presented with signs of acute hypoadrenocorticism without congestive heart failure. All dogs recovered to normal cardiac size and function with therapy. Hypoadrenocorticism should be considered as a differential diagnosis in dogs that present with ventricular dilation and systolic dysfunction if there are other indicators in the clinical and laboratory testing. Additionally, a thorough cardiac evaluation should be recommended for dogs that are found to have a heart murmur at the time of diagnosis of hypoadrenocorticism. |
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| Keywords: | Addison's disease Cardiomyopathy Reversible |
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