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Suspected sequential left atrial ruptures in a dog with myxomatous mitral valve disease
Affiliation:1. Department of Veterinary Medical Sciences, Alma Mater Studiorum – University of Bologna, via Tolara di Sopra 50, 40064 Ozzano dell''Emilia, Italy;2. Clinica Veterinaria San Sebastiano, via Boari 22, 04026 Minturno, Italy;1. VCA West Los Angeles Animal Hospital, 1900 S Sepulveda Blvd, Los Angeles, CA 90025, USA;2. University of Wisconsin-Madison School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USA;3. Veterinary Specialty and Emergency Center of Thousand Oaks, 2967 North Moorpark Road, Thousand Oaks, CA 91360, USA;1. Department of Veterinary Medical Sciences, Alma Mater Studiorum – University of Bologna, via Tolara di Sopra 50, 40064, Ozzano dell''Emilia, Italy;2. Freelance Veterinary Cardiologist, Bologna, Italy;3. Clinica Veterinaria Sasso Marconi, viale Verde 7, 40037, Sasso Marconi, Italy;4. Clinica Veterinaria San Sebastiano, via Boari 22, 04026, Minturno, Italy;5. Department of Veterinary Sciences, University of Parma, Strada del Taglio 10, 43126 Parma, Italy;1. Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 28 College Ave W, Guelph, Ontario, N1G 2W1, Canada;2. Hospital Veterinario UCV y Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria y Ciencias Experimentales, Universidad Catolica de Valencia San Vicente Martir, Valencia, Spain;3. Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown, PE, C1A 4P3, Canada;1. Veterinary Cardiology Consultancy, Leamington Road, Kenilworth, CV8 2AA, UK;2. Willows Veterinary Centre & Referral Service, Highlands Road, West Midlands, B90 4NH, UK;3. HeartVets, Porthcawl, UK;4. HeartVets, Whitestone, Exeter, EX4 2HP, UK;5. Hospital for Small Animals, Royal (Dick) School of Veterinary Studies & the Roslin Institute, University of Edinburgh, Roslin, EH25 9RG, UK;6. University Hospital for Companion Animals, 16 Dyrlaegevej, University of Copenhagen, 1870 Frederiksberg, Copenhagen, Denmark;7. AniCura Oslo Animal Hospital, Hoffsveien 70c, 0377, Oslo, Norway;1. Friendship Hospital for Animals, 4105 Brandywine St NW, Washington, DC 20016, USA;2. VCA West Los Angeles Animal Hospital, 1900 S Sepulveda Blvd, Los Angeles, CA 90025, USA;3. Oradell Animal Hospital, 580 Winters Ave, Paramus NJ 07652, USA;4. ACCESS-Los Angeles, 9599 Jefferson Blvd, Culver City, CA 90232, USA;5. Veterinary Specialty and Emergency Center Thousand Oaks, 2967 North Moorpark Road, Thousand Oaks, CA 91360, USA;6. ACCESS-South Bay, 2551 W 190th St. Torrance, CA 90504, USA;7. VCA Veterinary Specialists of the Valley, 22123 Ventura Blvd, Woodland Hills, CA 91364, USA
Abstract:An 11-year-old mixed breed dog was presented with exercise intolerance and syncope. At admission, transthoracic echocardiography revealed myxomatous mitral valve disease (MMVD) associated with severe left atrial (LA) enlargement and moderate anechoic pericardial effusion with a hyperechoic density suggestive of a thrombus. Rupture of the LA free wall secondary to MMVD was suspected, and medical therapy with furosemide and pimobendan was initiated. After one month, recheck echocardiography showed mild anechoic pericardial effusion and an acquired atrial septal defect with a left-to-right intracardiac shunting flow. In light of the dog's history, the latter finding was suspected to be secondary to a further rupture of the LA wall due to MMVD, this time affecting the interatrial septum. The images described here allow us to suspect that sequential LA wall ruptures developed over time in the same subject affected by MMVD, a clinical presentation not previously described in veterinary medicine.
Keywords:Atrial septal defect  Canine  Echocardiography  Pericardial effusion  Pericardial thrombus
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