酪蛋白酶解物对宫内生长迟缓新生仔猪小肠生长发育的影响

为探讨酪蛋白酶解物对宫内生长迟缓仔猪小肠生长发育的影响，选择胎儿在母体内发育迟缓（IUGR）初生仔猪15头，分为新生对照组（N）、酪蛋白组（C）和酪蛋白酶解物组（CH），以牛乳为基础日粮，C组用1．5％酪蛋白溶液取代10％（体积分数）的牛乳，CH组用1．5％酪蛋白酶解液取代10％（体积分数）的牛乳，人工饲喂3d后宰杀取样。结果表明：CH组仔猪小肠黏膜DNA含量及麦芽糖酶活性较N组显著提高（P〈0．05），而c组与N组相比未发生显著变化（P〉0．05）。此外，与N组仔猪相比，C组仔猪小肠各段绒毛高度都有不同程度降低（P〉0．05），而CH组仔猪小肠各段绒毛高度与N组仔猪接近，未有明显变化。提示：酪蛋白酶解物有刺激新生IUGR仔猪小肠黏膜上皮细胞的增殖和提高麦芽糖酶活性的趋势。

Effects of casein hydrolysate on the intestinal growth and development in intrauterine growth retardation neonatal piglets

The effects of casein hydrolysate on the growth and development of small intestine in intrauterine growth retardation(IUGR)piglets were examined in this study.Fifteen piglets were selected and divided into newborn control group(N),casein group(C)and casein hydrolysate group(CH).The cow-milk was taken as the basic feed,piglets in groups C and CH were fed milk substituted 1.5% casein and 1.5% casein hydrolysate solution for 10% milk,respectively.The piglets were slaughtered and sampled after feeding 3 days.The results indicated that the contents of DNA and the total activity of maltase of small intestine mucosa in groups CH were significantly increased than those in group N(P<0.05),but no changes were found between group N and group C(P>0.05).In addition,the villus height of small intestine in group C was decreased than that in group N,but no changes were found between group N and group CH(P>0.05).In conclusion,the casein hydrolysate showed tendency to stimulate the proliferation of the epithelium cell and increased the total activity of maltase in newborn IUGR piglets.