Enhanced intestinal permeability to 51Cr-labeled EDTA in dogs with small intestinal disease |
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Authors: | E J Hall R M Batt |
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Institution: | Department of Veterinary Pathology, University of Liverpool, UK. |
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Abstract: | Intestinal permeability in dogs with small intestinal disease was measured by quantitation of 24-hour urinary excretion of 51Cr-labeled EDTA following intragastric administration. Permeability was high in dogs with a variety of naturally acquired small intestinal diseases including wheat-sensitive enteropathy of Irish Setters, small intestinal bacterial over-growth, and giardiasis, and permeability was decreased after successful treatment. These findings indicate that the assessment of intestinal permeability may be a useful technique for detecting small intestinal disease and for monitoring the efficacy of treatment in dogs. |
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