Intradural extramedullary granular cell tumour in a cat |
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| Authors: | A Valentini S Canal M T Mandara F Balducci M Bernardini |
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| Institution: | 1. Department of Animal Medicine, Production and Health, University of Padova, 35020 Legnaro, Italy;2. Neurology Unit, Portoni Rossi Veterinary Hospital, 40069 Zola Predosa, Italy;3. Department of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy;4. Department of Animal Medicine, Production and Health, University of Padova, 35020 Legnaro, Italy
Neurology Unit, Portoni Rossi Veterinary Hospital, 40069 Zola Predosa, Italy |
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| Abstract: | A 7-year-old domestic shorthair cat was evaluated for progressive paraparesis, inability to jump, a paralysed tail and inability to void the bladder. Neurologic examination was consistent with a L4-S3 localisation. Survey radiographs of the lumbar vertebral column revealed L4-L7 vertebral body remodelling. A pre-contrast T1-weighted hyperintense, diffusely enhancing intradural lesion extending from L4 to S1 vertebral bodies was detected by MRI. Large, mesenchymal, round-to-polygonal cells arranged in nests or sheets were found on histologic examination at post mortem. These cells were characterised by abundant intracytoplasmic PAS-positive, diastase-resistant granules and positive immunoexpression of vimentin, S-100, neuron-specific enolase and desmin. This is the first report of a spinal granular cell tumour in a cat. |
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