National Taiwan University Veterinary Hospital, College of Bio-Resources and Agriculture, National Taiwan University, Taipei City, Taiwan;2. Graduate Institute of Microbiology and Public Health, College of Veterinary Medicine, National Chung-Hsing University, Taichung City, Taiwan;3. Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan;4. National Taiwan University Veterinary Hospital, College of Bio-Resources and Agriculture, National Taiwan University, Taipei City, Taiwan;5. Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung City, Taiwan;6. Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei City, Taiwan;7. Institute of Veterinary Clinical Science, School of Veterinary Medicine, College of Bio-Resources and Agriculture, National Taiwan University, Taipei City, Taiwan