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12株中国伊氏锥虫对小鼠的毒力试验
引用本文:周勇志,沈杰,何国声,周金林.12株中国伊氏锥虫对小鼠的毒力试验[J].中国预防兽医学报,2007,29(6):432-434.
作者姓名:周勇志  沈杰  何国声  周金林
作者单位:中国农业科学院上海兽医研究所,农业部寄生虫学重点开放实验室,上海,200232
基金项目:畜禽重要寄生虫虫种资源的收集与保存项目
摘    要:为了确定中国伊氏锥虫各株的毒力强弱,对中国伊氏锥虫:安徽水牛株(AHB)、广东阳江水牛株(GDB_1)、广东水牛株(GDB_2)、广东马株(GDH)、广西骡株(GXM)、湖北骡株(HBM)、湖南水牛株(HNB)、江苏高邮水牛株(JSB_1)、江苏盱眙水牛株(JSB_2)、新疆骆驼株(XJCA)、云南水牛株(YNB)、浙江水牛株(ZJB)进行小鼠的毒力试验。以各组鼠死亡率和平均存活天数作为毒力强弱的主要依据。结果表明最强致死率为100%,最弱30%;致死所需时间平均为7.5 d~25 d。对小鼠的致病力强弱依次是:AHB>YNB>GDB_2>XJCA>HBM>HNC>JSB_1>GXM>GDB_1>GDH>JSB_2>ZJB。提示不同株的毒力差异显著,测定结果可为伊氏锥虫相关科学研究选株提供依据。

关 键 词:伊氏锥虫  感染  毒力
文章编号:1008-0589(2007)06-0432-03
修稿时间:2006-10-25

Virulence of 12 Chinese trypanosoma evansi strains in mice
ZHOU Yong-zhi,SHEN Jie,HE Guo-sheng,ZHOU Jin-lin.Virulence of 12 Chinese trypanosoma evansi strains in mice[J].Chinese Journal of Preventive Veterinary Medicine,2007,29(6):432-434.
Authors:ZHOU Yong-zhi  SHEN Jie  HE Guo-sheng  ZHOU Jin-lin
Institution:Shanghai Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Key Laboratory for Animal Parasitology of Ministry of Agriculture, Shanghai 200232, China
Abstract:To study the virulence of different Chinese trypanosoma evansi strains,groups of healthy mice were inoculated with trypanosoma evansi AHB,GDB_1,GDB_2,GDH,GXM,HBM,HNC,JSB_1,JSB_2,XJCA,YNB and ZJB strains,respectively. The virulence of each strain was determined by animal mortality and average death time.The results showed that the mortality of inoculated mice range from 30% to 100% depending on trypanosoma evansi strains,with the average death time of 7.5 days to 25 days.The virulence of the 12 strains ranked from strong to weak is AHB>YNB>GDB_2>XJCA>HBM>HNC>JSB_1>GXM>GDB_1>GDH>JSB_2>ZJB.
Keywords:trypanosoma evansi  infection  virulence
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