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银环蛇毒素及其基因工程研究进展
引用本文:胡延春,贾艳,张乃生,欧阳红生. 银环蛇毒素及其基因工程研究进展[J]. 动物医学进展, 2003, 24(3): 15-18
作者姓名:胡延春  贾艳  张乃生  欧阳红生
作者单位:1. 塔里木农垦大学动物科技学院,新疆,阿拉尔,843300;解放军军需大学军事兽医系,吉林,长春,130062
2. 塔里木农垦大学动物科技学院,新疆,阿拉尔,843300
3. 解放军军需大学军事兽医系,吉林,长春,130062
摘    要:文章阐述了银环蛇毒素的特性、成分、蛋白质结构及其 c DNA和基因组 DNA,以及各种银环蛇毒素的克隆和表达研究概况。α,β、κ和γ-银环蛇毒素在结构上具有高度的同源性 ,在应用研究方面具有特殊的功能 ,主要应用在医学药理学、分子生物学和分子免疫学等方面。由于银环蛇毒分子量小 ,活性强 ,利用基因工程生产已成为开发相关产品的重要途径

关 键 词:银环蛇毒素  结构功能  克隆与表达
文章编号:1007-5038(2003)03-0015-04
修稿时间:2002-09-26

Advances of Research of Snake Venom from Bungarus Multicinctus and Genetic Engineering
HU Yan chun ,JIA Yan ,ZHANG Nai sheng ,OUYANG Hong sheng. Advances of Research of Snake Venom from Bungarus Multicinctus and Genetic Engineering[J]. Progress In Veterinary Medicine, 2003, 24(3): 15-18
Authors:HU Yan chun   JIA Yan   ZHANG Nai sheng   OUYANG Hong sheng
Affiliation:HU Yan chun 1,JIA Yan 1,ZHANG Nai sheng 2,OUYANG Hong sheng 2
Abstract:It has explained characteristics,ingredients,protein structures,cDNA,genome DNA about bungarotoxins from Bungarus multicinctus in this paper,as well as progesses of research for cloning and expression of several bungarotoxins.In structure,alpha,beta,kappa and gamma bungarotoxin are high homology,but they have special functions, repectively. They are mainly applied to medical pharmacology, molecular biology and immunology, and so on. It has important meaning that taking advantage of genetic engineering develops bungarotoxins products.
Keywords:bungarotoxins from bungarus multicinctus  structure and function  cloning and expression
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